• Participation in “Cells in Motion”

    • Management Board member of the CiM-IMPRS Graduate Programme

  • News & views

  • Papers in the research focus “cell dynamics and imaging”

    2021

    Aprea I, Nothe-Menchen T, Dougherty GW, Raidt J, Loges NT, Kaiser T, Wallmeier J, Olbrich H, Strunker T, Kliesch S, Pennekamp P, Omran H. Motility of efferent duct cilia aids passage of sperm cells through the male reproductive system. Mol Hum Reprod 2021;27Abstract
    Jeschke JK, Biagioni C, Schierling T, Wagner IV, Borgel F, Schepmann D, Schuring A, Kulle AE, Holterhus PM, von Wolff M, Wunsch B, Nordhoff V, Strunker T, Brenker C. The Action of Reproductive Fluids and Contained Steroids, Prostaglandins, and Zn(2+) on CatSper Ca(2+) Channels in Human Sperm. Front Cell Dev Biol 2021;9: 699554. Abstract
    Kierzek M, Deal PE, Miller EW, Mukherjee S, Wachten D, Baumann A, Kaupp UB, Strunker T, Brenker C. Simultaneous recording of multiple cellular signaling events by frequency- and spectrally-tuned multiplexing of fluorescent probes. Elife 2021;10Abstract

    2020

    Dougherty GW, Mizuno K, Nothe-Menchen T, Ikawa Y, Boldt K, Ta-Shma A, Aprea I, Minegishi K, Pang Y-P, Pennekamp P, Loges NT, Raidt J, Hjeij R, Wallmeier J, Mussaffi H, Perles Z, Elpeleg O, Rabert F, Shiratori H, Letteboer SJ, Horn N, Young S, Strunker T, Stumme F, Werner C, Olbrich H, Takaoka K, Ide T, Twan WK, Biebach L, Grosse-Onnebrink J, Klinkenbusch JA, Praveen K, Bracht DC, Hoben IM, Junger K, Gutzlaff J, Cindric S, Aviram M, Kaiser T, Memari Y, Dzeja PP, Dworniczak B, Ueffing M, Roepman R, Bartscherer K, Katsanis N, Davis EE, Amirav I, Hamada H, Omran H. CFAP45 deficiency causes situs abnormalities and asthenospermia by disrupting an axonemal adenine nucleotide homeostasis module. Nat Commun 2020;11: 5520. Abstract
    Schiffer C, Rieger S, Brenker C, Young S, Hamzeh H, Wachten D, Tuttelmann F, Ropke A, Kaupp UB, Wang T, Wagner A, Krallmann C, Kliesch S, Fallnich C, Strunker T. Rotational motion and rheotaxis of human sperm do not require functional CatSper channels and transmembrane Ca(2+) signaling. Embo J 2020: e102363. Abstract
    Wang T, Young S, Krenz H, Tuttelmann F, Ropke A, Krallmann C, Kliesch S, Zeng X-H, Brenker C, Strunker T. The Ca(2+) channel CatSper is not activated by cAMP/PKA signaling but directly affected by chemicals used to probe the action of cAMP and PKA. J Biol Chem 2020;295: 13181-13193. Abstract

    2018

    Brenker C, Rehfeld A, Schiffer C, Kierzek M, Kaupp UB, Skakkebaek NE, Strunker T. Synergistic activation of CatSper Ca2+ channels in human sperm by oviductal ligands and endocrine disrupting chemicals. Hum Reprod 2018;33: 1915-1923. Abstract
    Brenker C, Schiffer C, Wagner IV, Tuttelmann F, Ropke A, Rennhack A, Kaupp UB, Strünker T. Action of steroids and plant triterpenoids on CatSper Ca(2+) channels in human sperm. Proc Natl Acad Sci U S A 2018;115: E344-E346. Abstract
    Rennhack A, Schiffer C, Brenker C, Fridman D, Nitao ET, Cheng Y-M, Tamburrino L, Balbach M, Stolting G, Berger TK, Kierzek M, Alvarez L, Wachten D, Zeng X-H, Baldi E, Publicover SJ, Benjamin Kaupp U, Strunker T. A novel cross-species inhibitor to study the function of CatSper Ca(2+) channels in sperm. Br J Pharmacol 2018;175: 3144-3161. Abstract