Beteiligung an „Cells in Motion“
- Forschungsinteressen: morphogenesis of tubular organs, cellular and molecular mechanisms that control epithelial tube size and shape, cell behaviour and tissue mechanics in cylindrical epithelia, dynamics of intracellular membrane and protein trafficking, structure and function of epithelial tricellular junctions, roles of hypoxia in development
- Cells-in-Motion-Professor für Morphogenese Tubulärer Organe
- Vorstandsmitglied des Cells in Motion Interfaculty Centres
- Mitglied im Graduiertenprogramm CiM-IMPRS
- Mitglied im Imaging Network – Mikroskopie
News & Themen
- Verbindungsstellen zwischen drei Zellen dienen als Pforten für den Stofftransport – Forscher der Universität Münster entschlüsseln, wie sich Zellkontakte in der Eizellentwicklung bei Taufliegen dynamisch umbauen
- Der lange Weg zu neuem Wissen: Stefan Luschnig erzählt, wie er ein Protein entdeckt hat
- „Meine Zeit würde ich am liebsten am Mikroskop verbringen“ – ein Interview mit Stefan Luschnig
Publikationen im Forschungsschwerpunkt „Zelldynamik und Bildgebung“
2022
Camelo C, Korte A, Jacobs T, Luschnig S. Tracheal tube fusion in Drosophila involves release of extracellular vesicles from multivesicular bodies. J Cell Sci 2022;135Abstract Gass MM, Borkowsky S, Lotz M-L, Siwek R, Schroter R, Nedvetsky P, Luschnig S, Rohlmann A, Missler M, Krahn MP. PI(4,5)P2 controls slit diaphragm formation and endocytosis in Drosophila nephrocytes. Cell Mol Life Sci 2022;79: 248. Abstract Labbaf Z, Petratou K, Ermlich L, Backer W, Tarbashevich K, Reichman-Fried M, Luschnig S, Schulte-Merker S, Raz E. A robust and tunable system for targeted cell ablation in developing embryos. Dev Cell 2022;57: 2026-2040.e5. Abstract 2021
Camelo C, Luschnig S. Cells into tubes: Molecular and physical principles underlying lumen formation in tubular organs. Curr Top Dev Biol 2021;143: 37-74. Abstract Isasti-Sanchez J, Munz-Zeise F, Lancino M, Luschnig S. Transient opening of tricellular vertices controls paracellular transport through the follicle epithelium during Drosophila oogenesis. Dev Cell 2021;56: 1083-1099.e5. Abstract 2020
Gross-Thebing S, Truszkowski L, Tenbrinck D, Sanchez-Iranzo H, Camelo C, Westerich KJ, Singh A, Maier P, Prengel J, Lange P, Huwel J, Gaede F, Sasse R, Vos BE, Betz T, Matis M, Prevedel R, Luschnig S, Diz-Munoz A, Burger M, Raz E. Using migrating cells as probes to illuminate features in live embryonic tissues. Sci Adv 2020;6: eabc5546. Abstract Wittek A, Hollmann M, Schleutker R, Luschnig S. The Transmembrane Proteins M6 and Anakonda Cooperate to Initiate Tricellular Junction Assembly in Epithelia of Drosophila. Curr Biol 2020;30: 4254-4262.e5. Abstract 2019
Sauerwald J, Backer W, Matzat T, Schnorrer F, Luschnig S. Matrix metalloproteinase 1 modulates invasive behavior of tracheal branches during entry into Drosophila flight muscles. Elife 2019;8: e48857. Abstract 2018
Beati H, Peek I, Hordowska P, Honemann-Capito M, Glashauser J, Renschler FA, Kakanj P, Ramrath A, Leptin M, Luschnig S, Wiesner S, Wodarz A. The adherens junction-associated LIM domain protein Smallish regulates epithelial morphogenesis. J Cell Biol 2018;217: 1079-1095. Abstract Loison O, Weitkunat M, Kaya-Copur A, Nascimento Alves C, Matzat T, Spletter ML, Luschnig S, Brasselet S, Lenne P-F, Schnorrer F. Polarization-resolved microscopy reveals a muscle myosin motor-independent mechanism of molecular actin ordering during sarcomere maturation. PLoS Biol 2018;16: e2004718. Abstract Nelson JO, Forster D, Frizzell KA, Luschnig S, Metzstein MM. Multiple Nonsense-Mediated mRNA Processes Require Smg5 in Drosophila. Genetics 2018;209: 1073-1084. Abstract 2017
Caviglia S, Flores-Benitez D, Lattner J, Luschnig S, Brankatschk M. Rabs on the fly: Functions of Rab GTPases during development. Small GTPases 2017: 1-10. Abstract Misra T, Baccino-Calace M, Meyenhofer F, Rodriguez-Crespo D, Akarsu H, Armenta-Calderon R, Gorr TA, Frei C, Cantera R, Egger B, Luschnig S. A genetically encoded biosensor for visualising hypoxia responses in vivo. Biol Open 2017;6: 296-304. Abstract Sauerwald J, Soneson C, Robinson MD, Luschnig S. Faithful mRNA splicing depends on the Prp19 complex subunit faint sausage and is required for tracheal branching morphogenesis in Drosophila. Development 2017;144: 657-663. Abstract 2016
Caviglia S, Brankatschk M, Fischer EJ, Eaton S, Luschnig S. Staccato/Unc-13-4 controls secretory lysosome-mediated lumen fusion during epithelial tube anastomosis. Nat Cell Biol 2016;18: 727-739. Abstract De Lella Ezcurra AL, Bertolin AP, Kim K, Katz MJ, Gandara L, Misra T, Luschnig S, Perrimon N, Melani M, Wappner P. miR-190 Enhances HIF-Dependent Responses to Hypoxia in Drosophila by Inhibiting the Prolyl-4-hydroxylase Fatiga. PLoS Genet 2016;12: e1006073. Abstract 2015
Byri S, Misra T, Syed ZA, Batz T, Shah J, Boril L, Glashauser J, Aegerter-Wilmsen T, Matzat T, Moussian B, Uv A, Luschnig S. The Triple-Repeat Protein Anakonda Controls Epithelial Tricellular Junction Formation in Drosophila. Dev Cell 2015;33: 535-548. Abstract