• Participation in “Cells in Motion”

    • Research interests: host-microbiota interactions in autoimmunity and cancer, gut commensal translocation and colonization of host tissues, microbiota-induced immune cell migration and activation in non-communicable diseases
    • Supervisor in the CiM-IMPRS Graduate Programme

  • Patents in the research focus “cell dynamics and imaging”

    • Vieira SM, Kriegel MA. “Compositions and methods of treating autoimmune disease by reducing enterococcus." U.S. Patent No. 11,058,756 B2, filed July 18, 2019

  • Papers in the research focus “cell dynamics and imaging”

    2023

    Pereira MS, Kriegel MA. Evolving concepts of host-pathobiont interactions in autoimmunity. Curr Opin Immunol 2023;80: 102265. Abstract
    Pereira MS, Kriegel MA. Translocating Lactobacillus torments tumors via tryptophan catabolism. Cell 2023;186: 1821-1823. Abstract

    2022

    Brito IL, Kriegel MA. Structural host immune-microbiota interactions. Curr Opin Struct Biol 2022;76: 102445. Abstract
    Dehner CA, Ruff WE, Greiling T, Pereira MS, Redanz S, McNiff J, Girardi M, Kriegel MA. Malignant T Cell Activation by a Bacillus Species Isolated from Cutaneous T-Cell Lymphoma Lesions. JID Innov 2022;2: 100084. Abstract
    Pereira MS, Redanz S, Kriegel MA. Skin Deep: The Role of the Microbiota in Cutaneous Autoimmunity. J Invest Dermatol 2022Abstract
    Yang Y, Nguyen M, Khetrapal V, Sonnert ND, Martin AL, Chen H, Kriegel MA, Palm NW. Within-host evolution of a gut pathobiont facilitates liver translocation. Nature 2022;607: 563-570. Abstract

    2020

    Fine RL, Manfredo Vieira S, Gilmore MS, Kriegel MA. Mechanisms and consequences of gut commensal translocation in chronic diseases. Gut Microbes 2020;11: 217-230. Abstract
    Ruff WE, Greiling TM, Kriegel MA. Host-microbiota interactions in immune-mediated diseases. Nat Rev Microbiol 2020;18: 521-538. Abstract

    2019

    Ruff WE, Dehner C, Kim WJ, Pagovich O, Aguiar CL, Yu AT, Roth AS, Vieira SM, Kriegel C, Adeniyi O, Mulla MJ, Abrahams VM, Kwok WW, Nussinov R, Erkan D, Goodman AL, Kriegel MA. Pathogenic Autoreactive T and B Cells Cross-React with Mimotopes Expressed by a Common Human Gut Commensal to Trigger Autoimmunity. Cell Host Microbe 2019;26: 100-113.e8. Abstract
    Zegarra-Ruiz DF, El Beidaq A, Iniguez AJ, Lubrano Di Ricco M, Manfredo Vieira S, Ruff WE, Mubiru D, Fine RL, Sterpka J, Greiling TM, Dehner C, Kriegel MA. A Diet-Sensitive Commensal Lactobacillus Strain Mediates TLR7-Dependent Systemic Autoimmunity. Cell Host Microbe 2019;25: 113-127.e6. Abstract

    2018

    Greiling TM, Dehner C, Chen X, Hughes K, Iniguez AJ, Boccitto M, Ruiz DZ, Renfroe SC, Vieira SM, Ruff WE, Sim S, Kriegel C, Glanternik J, Chen X, Girardi M, Degnan P, Costenbader KH, Goodman AL, Wolin SL, Kriegel MA. Commensal orthologs of the human autoantigen Ro60 as triggers of autoimmunity in lupus. Sci Transl Med 2018;10Abstract
    Manfredo Vieira S, Hiltensperger M, Kumar V, Zegarra-Ruiz D, Dehner C, Khan N, Costa FRC, Tiniakou E, Greiling T, Ruff W, Barbieri A, Kriegel C, Mehta SS, Knight JR, Jain D, Goodman AL, Kriegel MA. Translocation of a gut pathobiont drives autoimmunity in mice and humans. Science 2018;359: 1156-1161. Abstract

    2017

    Gulden E, Vudattu NK, Deng S, Preston-Hurlburt P, Mamula M, Reed JC, Mohandas S, Herold BC, Torres R, Vieira SM, Lim B, Herazo-Maya JD, Kriegel M, Goodman AL, Cotsapas C, Herold KC. Microbiota control immune regulation in humanized mice. JCI Insight 2017;2Abstract

    2012

    Kriegel MA, Rathinam C, Flavell RA. Pancreatic islet expression of chemokine CCL2 suppresses autoimmune diabetes via tolerogenic CD11c+ CD11b+ dendritic cells. Proc Natl Acad Sci U S A 2012;109: 3457-3462. Abstract

    2011

    Kriegel MA, Sefik E, Hill JA, Wu H-J, Benoist C, Mathis D. Naturally transmitted segmented filamentous bacteria segregate with diabetes protection in nonobese diabetic mice. Proc Natl Acad Sci U S A 2011;108: 11548-11553. Abstract