Participation in “Cells in Motion”
- Research interests: structural biology, cryoEM, peroxisomal biogenesis, AAA ATPases, pore forming toxins, protein translocation
- Supervisor in the CiM-IMPRS Graduate Programme
News & views
- Microscopes: Looking deep into hidden worlds – Five high-performance microscopes at the University of Münster
- A close-up of biological nanomachines: Researchers at Münster University take a deep look at peroxisomal processes
- “This degree of detail is astonishing”: High-performance cryogenic electron microscope at the Center for Soft Nanoscience
Papers in the research focus “cell dynamics and imaging”
2022
Klink BU, Herrmann E, Antoni C, Langemeyer L, Kiontke S, Gatsogiannis C, Ungermann C, Raunser S, Kümmel D. Structure of the Mon1-Ccz1 complex reveals molecular basis of membrane binding for Rab7 activation. Proc Natl Acad Sci USA 2022;119: e2121494119. Abstract 2021
Chen M, Blum D, Engelhard L, Raunser S, Wagner R, Gatsogiannis C. Molecular architecture of black widow spider neurotoxins. Nat Commun 2021;12: 6956. Abstract Kudruk S, Pottanam Chali S, Linard Matos AL, Bourque C, Dunker C, Gatsogiannis C, Ravoo BJ, Gerke V. Biodegradable and Dual-Responsive Polypeptide-Shelled Cyclodextrin-Containers for Intracellular Delivery of Membrane-Impermeable Cargo. Adv Sci (Weinh) 2021: e2100694. Abstract 2020
Lill P, Hansen T, Wendscheck D, Klink BU, Jeziorek T, Vismpas D, Miehling J, Bender J, Schummer A, Drepper F, Girzalsky W, Warscheid B, Erdmann R, Gatsogiannis C. Towards the molecular architecture of the peroxisomal receptor docking complex. Proc Natl Acad Sci U S A 2020Abstract 2019
Gatsogiannis C, Balogh D, Merino F, Sieber SA, Raunser S. Cryo-EM structure of the ClpXP protein degradation machinery. Nat Struct Mol Biol 2019;26: 946-954. Abstract 2018
Gatsogiannis C, Merino F, Roderer D, Balchin D, Schubert E, Kuhlee A, Hayer-Hartl M, Raunser S. Tc toxin activation requires unfolding and refolding of a beta-propeller. Nature 2018;563: 209-213. Abstract 2016
Gatsogiannis C, Merino F, Prumbaum D, Roderer D, Leidreiter F, Meusch D, Raunser S. Membrane insertion of a Tc toxin in near-atomic detail. Nat Struct Mol Biol 2016;23: 884-890. Abstract