• Participation in “Cells in Motion”

    • Research interests: molecular infection biology, bacterial cell infections, host-pathogen interaction, pathogen-induced host cell modifications, molecular pathogenesis
    • Supervisor in the CiM-IMPRS Graduate Programme

  • News & views

  • Papers in the research focus “cell dynamics and imaging”

    2022

    Bäumer N, Scheller A, Wittmann L, Faust A, Apel M, Nimmagadda SC, Geyer C, Grunert K, Kellmann N, Peipp M, Kailayangiri S, Gutierrez Suburu ME, Strassert CA, Schenk M, Greune L, Rüter C, Dersch P, Hartmann W, Rossig C, Neri D, Müller-Tidow C, Schwöppe C, Schliemann C, Khandanpour C, Lenz G, Berdel WE, Bäumer S. Electrostatic anti-CD33-antibody–protamine nanocarriers as platform for a targeted treatment of acute myeloid leukemia. J Hematol Oncol 2022;15Abstract
    Baumer N, Tiemann J, Scheller A, Meyer T, Wittmann L, Suburu MEG, Greune L, Peipp M, Kellmann N, Gumnior A, Brand C, Hartmann W, Rossig C, Muller-Tidow C, Neri D, Strassert CA, Ruter C, Dersch P, Lenz G, Koeffler HP, Berdel WE, Baumer S. Targeted siRNA nanocarrier: a platform technology for cancer treatment. Oncogene 2022;41: 2210-2224. Abstract
    Faust A, Baumer N, Schlutermann A, Becht M, Greune L, Geyer C, Ruter C, Margeta R, Wittmann L, Dersch P, Lenz G, Berdel WE, Baumer S. Tumor-Cell-Specific Targeting of Ibrutinib: Introducing Electrostatic Antibody-Inhibitor Conjugates (AiCs). Angew Chem Int Ed Engl 2022;61: e202109769. Abstract

    2021

    Bielaszewska M, Greune L, Bauwens A, Dersch P, Mellmann A, Ruter C. Virulence Factor Cargo and Host Cell Interactions of Shiga Toxin-Producing Escherichia coli Outer Membrane Vesicles. Methods Mol Biol 2021;2291: 177-205. Abstract

    2020

    Derbise A, Echenique-Rivera H, Garcia-Lopez M, Beau R, Mattei M, Varet H, Dersch P, Pizarro-Cerda J. Bread Feeding Is a Robust and More Physiological Enteropathogen Administration Method Compared to Oral Gavage. Infect Immun 2020;88: e00810-19. Abstract
    Mühlen S, Ramming I, Pils MC, Koeppel M, Glaser J, Leong J, Flieger A, Stecher B, Dersch P. Identification of Antibiotics That Diminish Disease in a Murine Model of Enterohemorrhagic Escherichia coli Infection. Antimicrob Agents Chemother 2020;64: e02159-19. Abstract
    Schäfer H, Beckert B, Frese CK, Steinchen W, Nuss AM, Beckstette M, Hantke I, Driller K, Sudzinova P, Krasny L, Kaever V, Dersch P, Bange G, Wilson DN, Turgay K. The alarmones (p)ppGpp are part of the heat shock response of Bacillus subtilis. PLoS Genet 2020;16: e1008275. Abstract
    Twittenhoff C, Heroven AK, Muhlen S, Dersch P, Narberhaus F. An RNA thermometer dictates production of a secreted bacterial toxin. PLoS Pathog 2020;16: e1008184. Abstract

    2017

    Nuss AM, Beckstette M, Pimenova M, Schmuhl C, Opitz W, Pisano F, Heroven AK, Dersch P. Tissue dual RNA-seq allows fast discovery of infection-specific functions and riboregulators shaping host-pathogen transcriptomes. Proc Natl Acad Sci U S A 2017;114: E791-E800. Abstract
    Pezoldt J, Pisano F, Heine W, Pasztoi M, Rosenheinrich M, Nuss AM, Pils MC, Prinz I, Forster R, Huehn J, Dersch P. Impact of CCR7 on T-Cell Response and Susceptibility to Yersinia pseudotuberculosis Infection. J Infect Dis 2017;216: 752-760. Abstract

    2013

    Schweer J, Kulkarni D, Kochut A, Pezoldt J, Pisano F, Pils MC, Genth H, Huehn J, Dersch P. The cytotoxic necrotizing factor of Yersinia pseudotuberculosis (CNFY) enhances inflammation and Yop delivery during infection by activation of Rho GTPases. PLoS Pathog 2013;9: e1003746. Abstract

    2006

    Heise T, Dersch P. Identification of a domain in Yersinia virulence factor YadA that is crucial for extracellular matrix-specific cell adhesion and uptake. Proc Natl Acad Sci U S A 2006;103: 3375-3380. Abstract