Cellular signaling platforms – from molecules to organisms
Poster
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Tissue differentiation and cellular functions in multicellular organisms require constant communication across cellular interfaces. Exchange of information and signals mostly occurs via assembly and disassembly of molecular platforms that serve as cellular decision-making hubs. In our collaborative research center CRC1348 we are investigating such contacts at various levels of organization, ranging from how particular plasma membrane domains are formed in isolated cells, at interfaces between neighboring cells, to the study of functional consequences of selected cellular interfaces in the organismal context. At our first international CRC1348 symposium, we are bringing together scientists to discuss the following topics: membrane trafficking, cell migration, mechanobiology, and vascular, epithelial and neuronal development. One major goal here is to identify common themes that connect the different levels of organization.
The meeting is also thought as a stepping stone for young group leaders from the Münster area who showcase as scientific organizers (M. Pitulescu and S. Rumpf) and as invited speakers (P. Bieling, M. Bohnert, M. Galic, M. Matis, S. Rumpf, B. Trappmann). This lineup is completed by internationally accomplished scientists from the United States, Switzerland, Sweden, the United Kingdom, and Germany, including the keynote speakers, Rüdiger Klein, Tomas Kirchhausen, and Kristy Red-Horse. The target audience are scientists from all career stages interested in the topics of the meeting.
No fees and no registration required.
Speaker
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© Uni Münster Program
June 6th, 2019
14.00 – 14.15 Welcome
Session 1: Neuronal development, chair S. Rumpf
14.15 – 15.00 Rüdiger Klein, Martinsried Cell-cell communication during brain development – a matter of attraction, repulsion, or partial cannibalism 15.00 – 15.30 Amparo Acker-Palmer, Frankfurt The neurovascular interface 15.30 – 16.00 Sebastian Rumpf, Muenster Tissue architecture determines severing sites during neurite pruning 16.00 – 16.30 coffee break
Session 2: Cellular Signaling Interfaces, chair M. Galic
16.30 – 17.00 Peter Bieling, Dortmund The limits to (actin) growth 17.00 – 17.30 Lucas Pelkmans, Zurich Crossing scales in single-cell biology 17.30 – 18.00 Milos Galic, Muenster Mechano-chemical self-organization determines search pattern in migratory cells June 7th, 2019
Session 3: Membrane traffic, chair M. Bohnert
09.00 – 09.30 Anne Spang, Basel PTCH regulates membrane homeostasis through a novel pathway in C. elegans 09.30 – 10.00 Christian Ungermann, Osnabrück Molecular mechanisms involved in organelle homeostasis 10.00 – 10.30 Maria Bohnert, Muenster Lipid droplet interfaces 10.30 – 11.00 coffee break
Session 4: Plasma membrane regulation, chair M. Schelhaas
11.00 – 11.45 Tomas Kirchhausen, Boston Imaging subcellular dynamics from molecules to multicellular organisms 11.45 – 12.15 Marko Kaksonen, Geneva Imaging the molecular mechanisms of clathrin- and actin-mediated endocytosis 12.15 – 12.45 Philippe Bastiaens, Dortmund SynMPS 12.45 – 14.30 lunch break / SFB 1348 researcher poster presentation
Session 5: From single cells to organisms, chair I. Bedzhov
14.30 – 15.00 Anne Grapin-Botton, Dresden Pancreatic organoids as a means to assess cell to cell signaling leading to differentiation and morphogenesis 15.00 – 15.30 Paul Martin, Bristol Inflammation in wound healing and cancer 15.30 – 16.00 Damian Brunner, Zurich Integrating cellular shape oscillation and tissue morphogenesis 16.00 – 16.30 coffee break
Session 6: Tissue morphogenesis I, chair M. Pitulescu
16.30 – 17.15 Kristy Red-Horse, Stanford Re-establishing developmental pathways to stimulate cardiac regeneration 17.15 – 17.45 Taija Mäkinen, Uppsala Heterogeneity in the lymphatic vasculature - towards understanding organ-specific functions and disease 17.45 – 18.15 Lilianna Solnica-Krezel, St. Louis Regulation of cell movements in zebrafish by Dachsous atypical cadherin 18.15 – 19.00 SFB 1348 researcher poster presentation
June 8th, 2019
Session 7: Tissue morphogenesis II, chair K. Tarbashevich
09.00 – 09.30 Roberto Mayor, London Rear-wheel drive for collective cell migration 09.30 – 10.00 Didier Stainier, Bad Nauheim Cardiac development and regeneration in zebrafish 10.00 – 10.30 Maja Matis, Muenster Mechanical control of tissue remodelling by Fat PCP pathway 10.30 – 11.00 coffee break
Session 8: Mechanical forces, chair B. Trappmann
11.00 – 11.30 Jochen Guck, Erlangen Biophysical tools to quantify phase transitions in cells 11.30 – 12.00 Carsten Grashoff, Muenster Piconewton sensitive biosensors to investigate adhesion mechanics in cells 12.00 – 12.30 Britta Trappmann, Muenster Regulation of angiogenic sprouting by the extracellular matrix