2024

Enantioselective Energy Transfer-Enabled Cyclization using a Privileged Al-Salen Photocatalyst
J. Soika, C. Onneken, T. Wiegmann, T. Morack, L. Lindfeld, M. Hebenbrock, C. Mück-Lichtenfeld, J. Neugebauer and R. Gilmour, ChemRxiv 2024, doi:10.26434/chemrxiv-2024-9g3qz.

149. Probing the Origin of Affinity in the GM1-Cholera Toxin Complex through Site-selective Editing with Fluorine
C. Jordan^§, T. Hayashi^§, A. Löbbert, J. Fan, C. S. Teschers, K. Siebold, M. Aufiero, F. Pape, E. Campbell, A. Axer, K. Bussmann, K. Bergander, J. Köhnke, A. D. Gossert and R. Gilmour, ACS Cent. Sci. 2024, 10, 1481–1489.

_{Highlighted in ACS Central Science: https://pubs.acs.org/doi/10.1021/acscentsci.4c01206}

148. Regioselective Fluorination of Allenes Enabled by I(I)/I(III) Catalysis
Z.-X. Wang, Y. Xu and R. Gilmour, Nature Communications 2024, 15, 5770.

147. A Fluorinated Sialic Acid Vaccine Lead Against Meningitis B and C
C. Jordan^§, K. Siebold^§, P. Priegue^§, P. H. Seeberger and R. Gilmour, J. Am. Chem. Soc. 2024, 146, 15366–15375.

146. Regio- and Stereo-Selective Isomerization of Borylated 1,3-Dienes Enabled by Selective Energy Transfer Catalysis
B. Kweon, L. Blank, J. Soika, A. Messara, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2024, e202404233.

145. Catalytic Ring Expanding Difluorination: An Enantioselective Platform to Access β,β-Difluorinated Carbocycles
L. Ruyet, C. Roblick, J. Häfliger, Z.-X. Wang, T. J. Stoffels, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2024, e202403957.

2023

144. Para-Selective Dearomatization of Phenols by I(I)/I(III) Catalysis-Based Fluorination
T. Stünkel, K. Siebold, D. Okumatsu, K. Murata, L. Ruyet, C. G. Daniliuc and R. Gilmour, Chem. Sci. 2023, 14, 13574 - 13580.

143. Regioselective, catalytic 1,1-difluorination of enynes
Z.-X. Wang, K. Livingstone, C. Hümpel, C. G. Daniliuc, C. Mück-Lichtenfeld and R. Gilmour, Nature Chemistry 2023, 10.1038/s41557-023-01344-5.

_{Highlighted by the University of Münster: https://www.uni-muenster.de/news/view.php?cmdid=13638
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142. Light Enabled Deracemization of Cyclopropanes by Al Salen Photocatalysis
C. Onneken, T. Morack, J. Soika, O. Sokolova, N. Niemeyer, C. Mück-Lichtenfeld, C. G. Daniliuc, J. Neugebauer and R. Gilmour, Nature 2023, 621, 753-759.

_{Highlighted as Synfact of the month by M. Lautens and A. Torelli: Synfacts 2023, 19, 1099. DOI: 10.1055/s-0042-1752274. https://www.thieme-connect.com/products/ejournals/html/10.1055/s-0042-1752274?device=mobile&innerWidth=980&offsetWidth=980
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Highlighted by Nature Asia: http://www.natureasia.com/ko-kr/nature/highlights/122927}

141. Integrating I(I)/I(III) Catalysis in Reaction Cascade Design Enables the Synthesis of gem-Difluorinated Tetralins from Cyclobutanols
J. Häfliger, L. Ruyet, N. Stübke, C. G. Daniliuc and R. Gilmour, Nature Communications 2023, 14, 3207.

140. Direct Observation of Triplet States in the Isomerization of Alkenylboronates by Energy Transfer Catalysis
T. J. B. Zähringer, M. Wienhold, R. Gilmour and C. Kerzig, J. Am. Chem. Soc. 2023, 145, 21576-21586.

_{Highlighted in Synfacts: B. List, K. Kryvous, Synfacts 2023, 19, 0819.}

139. Forging Medium Rings via I(I)/I(III)-Catalyzed Diene Carbofunctionalization
Y.-J. Yu, J. Häfliger, Z.-X. Wang, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2023, e202309789.
_{Open access}

138. Geometric Isomerisation of Bifunctional Vinyl Fluoride Linchpins: Stereodivergence in Amide and Polyene Bioisostere Synthesis
M. Wienhold, B. Kweon, C. McLaughlin, M Schmitz, T. J. B. Zähringer, C. G. Daniliuc, C. Kerzig and R. Gilmour, Angew. Chem. Int. Ed. 2023, e202304150.
_{Hot Paper
Open acces}

137. Fluorinated Carbohydrates for ¹⁸F-Positron Emission Tomography (PET)
E. Campbell, C. Jordan and R. Gilmour, Chem. Soc. Rev. 2023, 52, 3599-3626.
_{Artwork featured on the front cover}

136. Catalytic, Regioselective 1,4-Fluorodifunctionalization of Dienes
Y.-J. Yu, M. Schäfer, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2023, 62, e202214906.
_{Highlighted in Synfacts: B. List, M. M. Poje, Synfacts 2023, 19, 0185.
Open access}

135. Fluorine-Directed Automated Mannoside Assembly
C. Teschers and R. Gilmour, Angew. Chem. Int. Ed. 2023, 135 e202213304. DOI numbers 10.1002/anie.202213304 and 10.1002/ange.202213304.
Press release: https://www.uni-muenster.de/news/view.php?cmdid=13047&lang=en
_{Open access}

134. Fluorocyclisation of Oximes to Isoxazolines via I(I)/I(III) Catalysis
J. Neufeld, C. G. Daniliuc and R. Gilmour, Helv. Chim. Acta 2023, e202200183.
_{Invited contribution for the special issue dedicated to the memory of the late Prof. Dr. Jack D. Dunitz FRS
Open access}

2022

133. Skeletal Ring Contractions via I(I)/I(III) Catalysis: Stereoselective Synthesis of cis-α,α-Difluorocyclopropanes
K. Livingstone, K. Siebold, S. Meyer, V. Martín-Heras, C. G. Daniliuc, and R. Gilmour, ACS Catal. 2022, 12, 14507–14516.
_{Open access}

132. Organophotocatalytic N–O Bond Cleavage of Weinreb Amides: Mechanism-Guided Evolution of a PET to ConPET Platform
J. Soika, C. McLaughlin, T. Neveselý, C. G. Daniliuc, J. J. Molloy and R. Gilmour, ACS Catal. 2022, 12, 10047-10056.

Previously ChemRxiv 2022, DOI: 10.26434/chemrxiv-2022-0fz0p
_{Highlighted in Org. Proc. Res. Dev.: https://pubs.acs.org/doi/pdf/10.1021/acs.oprd.2c00309}

131. Cyclopropene Activation via I(I)/I(III) Catalysis: Proof of Principle and Application in Direct Tetrafluorination
S. Meyer, L. Göbel, K. Livingstone, C. Roblick, C. G. Daniliuc and R. Gilmour, Tetrahedron 2022, 132925.
_{open access
Invited contribution for the special edition dedicated to Prof. Dr. F. Schoenebeck.}

130. Stereocontrolled Synthesis of Fluorinated Isochromans via Iodine(I)/Iodine(III) Catalysis
J. Häfliger, O. O. Sokolova, M. Lenz, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, e202205277. DOI:10.1002/anie.202205277 and 10.1002/ange.202205277.
_{Selected as HOT PAPER}

129. Regio- and Enantioselective Intermolecular Aminofluorination of Alkenes via Iodine(I)/Iodine(III) Catalysis
M. Schäfer, T. Stünkel, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, e202205508. DOI numbers 10.1002/anie.202205508 and 10.1002/ange.202205508
_{Selected as HOT PAPER}

Previously ChemRxiv 2022 DOI: 10.26434/chemrxiv-2022-jnslk

128. Advances in the E → Z Isomerization of Alkenes using Small Molecule Photocatalysts
T. Neveselý, M. Wienhold, J. J. Molloy and R. Gilmour, Chem. Rev. 2022, 122, 2650-2694.
_{Invited contribution for the thematic issue Photochemical Catalytic Processes.}

127. Leveraging the n→π* Interaction in Alkene Isomerisation by Selective Energy Transfer Catalysis
T. Neveselý, J. J. Molloy, C. McLaughlin, L. Brüss, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2022, 61, e202113600.

126. Leveraging fluorine (stereoelectronic) effects in catalysis in The Chemistry of Organofluorine Compounds
J. Neufeld, K. Livingstone and R. Gilmour, in The Chemistry of Organofluorine Compounds, Patai´s Chemistry of Functional Groups (2022) (Eds. I. Marek, V. Gouverneur, M. Gandelman), Wiley-VCH Verlag GmbH & Co, Weinheim.
 

2021

125. Enantiodivergent Prenylation via Deconjugative Isomerization
T. Morack, C. Onneken, H. Nakakohara, C. Mück-Lichtenfeld and R. Gilmour, ACS Catal. 2021, 11, 11929–11937.

124. Illuminating Anti-Hydrozirconation: Controlled Geometric Isomerization of an Organometallic Species
T. Hostmann, T. Nevesely and R. Gilmour, Chem. Sci. 2021, 12, 10643 - 10648.

123. Expanding Organofluorine Chemical Space: The Design of Chiral Fluorinated Isosteres Enabled by I(I)/I(III) Catalysis
S. Meyer, J. Häfliger and R. Gilmour, Chem. Sci. 2021, 12, 10686 - 10695
_{Part of the themed collection 2021 Chemical Science HOT article Collection.}

122. An I(I)/I(III) Catalysis Route to the Heptafluoroisopropyl Group: A Privileged Module in Contemporary Agrochemistry
V. Martín-Heras, C. G. Daniliuc and R. Gilmour, Synthesis 2021, 53, 4203-4212.
_{Invited contribution for the special edition in honour of Prof. Sarah Reisman}

^{SYNTHESIS Best paper Award 2021}

121. Emerging Fluorinated Motifs: Synthesis, Properties, and Applications (book review)
J. Neufeld and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 20592-20593.

120. Difluorination of α-(bromomethyl)styrenes via I(I)/I(III) catalysis: facile access to electrophilic linchpins for drug discovery
J. Häfliger, K. Livingstone, C. G. Daniliuc and R. Gilmour, Chem. Sci. 2021, 12, 6148–6152.

119. Trifluorinated Tetralins via I(I)/I(III)-Catalysed Ring Expansion: Programming Conformation by [CH₂CH₂] → [CF₂CHF] Isosterism
J. Neufeld, T. Stünkel, C. Mück-Lichtenfeld, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 13647-13651.

118. Oligodendroglial Glycolipids in (Re) Myelination: Implications for Multiple Sclerosis Research
L. Nowack, C. S. Teschers, S. Albrecht, R. Gilmour, Nat. Prod. Rep. 2021, 38, 890-904.
DOI: 10.1039/D0NP00093K.
_{Artwork featured on the front cover.}

117. A Chiral, Pentafluorinated Isopropyl Group via Iodine(I)/(III) Catalysis
S. Meyer, J. Häfliger, M. Schäfer, J. J. Molloy, C. G. Daniliuc, and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 6430-6434.
_{Highlighted in Synfacts: B. List, D. Díaz-Oviedo, Synfacts 2021, 17, 0443.}

116. Coumarins by Direct Annulation: β-Borylacrylates as Ambiphilic C3-Synthons
M. Wienhold, J. J. Molloy, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2021, 60, 685-689.
_{Highlighted in Synfacts: P. Knochel, D. Djukanovic, Synfacts 2020, 16, 1444.}

115. Enhancing Glycan Stability via Site-Selective Fluorination: Modulating Substrate Orientation by Molecular Design
A. Axer, R. P. Jumde, S. Adam, A. Faust, M. Schäfers, M. Fobker, J. Koehnke, A. K. H. Hirsch and R. Gilmour, Chem. Sci. 2021, 12, 1286-1294.
_{First posted on Chemrxiv 2020, DOI:10.26434/chemrxiv.12656210.
Highlighted as a "hot article" by Chemical Science.}

2020

114. Boron-enabled geometric isomerization of alkenes via selective energy-transfer catalysis J. J. Molloy, M. Schäfer, M. Wienhold, T. Morack, C. G. Daniliuc and R. Gilmour, Science 2020, 369, 302-306. Abstract      Reprint     Full text Highlighted in Synform: https://www.thieme-connect.de/products/ejournals/pdf/10.1055/s-0039-1691232.pdf Highlighted by TCI America: https://www.tcichemicals.com/US/en/product/tci-topics/ProductHighlights_20200831 Highlighted in Synfacts: https://www.thieme-connect.de/products/ejournals/abstract/10.1055/s-0040-1707376 Highlighted in EurekAlert! AAAS: https://www.eurekalert.org/pub_releases/2020-07/uom-rsa071620.php Highlighted in ScienMag: https://scienmag.com/researchers-solve-a-long-standing-problem-in-organic-chemistry/ Highlighted in Phys.Org: https://phys.org/news/2020-07-chemists-bioinspired-strategy-synthesis-polyenes.html Highlighted in News Beezer: https://newsbeezer.com/chemists-are-developing-a-bio-inspired-strategy-for-the-controlled-synthesis-of-polyenes/ Highlighted in idw - News: https://idw-online.de/de/news751330 Highlighted by the WWU Münster: https://www.uni-muenster.de/news/view.php?cmdid=1114 Highlighted by the Cells in Motion Interfaculty Center at the WWU Münster: https://www.uni-muenster.de/Cells-in-Motion/de/ Highlighted in Bioengineer.org: https://bioengineer.org/researchers-solve-a-long-standing-problem-in-organic-chemistry/ Highlighted in innovations report: https://www.innovations-report.de/html/berichte/biowissenschaften-chemie/forscher-loesen-langjaehriges-raetsel-der-organischen-chemie-entwicklung-eines-bioinspirierten-wegs-polyene-zu-formen.html Highlighted in Laboratory Equipment: https://www.laboratoryequipment.com/566344-Researchers-Solve-a-Long-standing-Problem-in-Organic-Chemistry/ Highlighted in ChemEurope: https://www.chemeurope.com/en/news/1167248/long-standing-problem-in-organic-chemistry-solved.html?pk_campaign=ca0066&WT.mc_id=ca0066 Highlighted in SciTechDaily: https://scitechdaily.com/long-standing-problem-in-organic-chemistry-finally-solved-by-researchers/ Highlighted in Infosurhoy: https://infosurhoy.com/science/long-standing-problem-in-organic-chemistry-finally-solved-by-researchers/ Highlighted in ScienceDaily: https://www.sciencedaily.com/releases/2020/07/200716163041.htm Highlighted in NewsCollective: https://newscollective.co.nz/chemists-develop-bioinspired-strategy-for-the-controlled-synthesis-of-polyenes-phys-org/ Highlighted in WorldNewsEra: https://worldnewsera.com/news/science/long-standing-problem-in-organic-chemistry-finally-solved-by-researchers/   First posted on Chemrxiv 2020, DOI:10.26434/chemrxiv.11982486.

113. Cooperative Activation Modes for Catalysis-Based Total Synthesis S. Meyer and R. Gilmour, Trends Chem. 2020, 2, 959-961.

112. Flow Photocleavage for Automated Glycan Assembly (AGA) C. S. Teschers and R. Gilmour, Org. Process Res. Dev. 2020, 10, 2234–2239. Part of the special edition “Flow Chemistry Enabling Efficient Synthesis”

111. Conformational Analysis of Acyclic α-Fluoro Sulfur Motifs N. Erdeljac, C. Mück-Lichtenfeld, C. G. Daniliuc and R. Gilmour, Chem. Eur. J. 2020, 26, 13704-13715.

110. Fluorohydration of Alkynes via I(I)/I(III)-Catalysis J. Neufeld, C. G. Daniliuc and R. Gilmour, Beilstein J. Org. Chem. 2020, 16, 1627-1635. Invited contribution for the special edition on organofluorine chemistry

109. Total Chemical Syntheses of the GM3 and F-GM3 Ganglioside Epitopes and Comparative Pre-Clinical Evaluation for Non-Invasive Imaging of Oligodendrocyte Differentiation T. J. Kieser, N. Santschi, L. Nowack, A. Axer, G. Kehr, S. Albrecht and R. Gilmour, ACS Chem. Neurosci. 2020, 11, 2129-2136.

108. Validating the 1,2-Difluoro (BITE) Motif as a Hybrid Bioisostere of CF3 and Et using Matrix Metalloproteases as Structural Probes N. Erdeljac, C. Thiehoff, R. Jumde, C. Daniliuc, S. Hoeppner, A. Faust, A. Hirsch and R. Gilmour, J. Med. Chem. 2020, 63, 6225-6237.

107. Enantioselective Synthesis of 3-Fluorochromanes via I(I)/I(III) Catalysis J. C. Sarie, C. Thiehoff, J. Neufeld, C. G. Daniliuc and R. Gilmour, Angew. Chem. Int. Ed. 2020, 59, 15069-15075. Highlighted by ChemViews: https://www.chemistryviews.org/details/ezine/11253871/Enantioselective_3-Fluorochromane_Synthesis.html Selected as a VIP paper

106. Contra-Thermodynamic E→Z Isomerization of Cinnamamides via Selective Energy Transfer Catalysis M. R. Becker, T. Morack, J. Robertson, J. B. Metternich, C. Mück-Lichtenfeld, C. Daniliuc, G A. Burley and R. Gilmour, Tetrahedron 2020, 76, 131198. Invited contribution

105. Halogen-Directed Chemical Sialylation: Pseudo-Stereodivergent Access to Marine Ganglioside Epitopes T. Hayashi, A. Axer, G. Kehr, K. Bergander and R. Gilmour, Chem. Sci. 2020, 11, 6527-6531.

104. Inverting External Asymmetric Induction via Selective Energy Transfer Catalysis: A Strategy to β-Chiral Phosphonate Antipodes C. Onneken, K. Bussmann and R. Gilmour, Angew. Chem. 2020, 132, 338-342; Angew. Chem. Int. Ed. 2020, 59, 330-334.

2019

103. Light-Enabled Enantiodivergence: Stereospecific Reduction of Activated Alkenes using a Single Organocatalyst Enantiomer T. Hostmann, J. J. Molloy, K. Bussmann and R. Gilmour, Org. Lett. 2019, 21, 10164-10168.

102. Sequential Energy Transfer Catalysis: A Cascade Synthesis of Angularly-Fused Dihydrocoumarins T. Neveselý, C. G. Daniliuc and R. Gilmour, Org. Lett. 2019, 21, 9724-9728.

101. Photocatalytic E→Z Isomerization of β-Ionyl Derivatives K. Livingstone, M. Tenberge, F. Pape, C. G. Daniliuc, C. Jamieson and R. Gilmour, Org. Lett. 2019, 21, 9677-9680.

100. Geometric E→Z Isomerisation of Vinyl Silanes by Selective Energy Transfer Catalysis: Stereodivergent Synthesis of Triarylethylenes via a Formal Anti-Metallometallation S. I. Faßbender, J. J. Molloy, C. Mück-Lichtenfeld and R. Gilmour, Angew. Chem. 2019, 131, 18792-18799; Angew. Chem. Int. Ed. 2019, 58, 18619-18626.

99. Stereocontrolled Synthesis of Tetrafluoropentanols: Multi-vicinal Fluorinated Alkane Units for Drug Discovery P. Bentler, N. Erdeljac, K. Bussmann, M. Ahlqvist, L. Knerr, K. Bergander, C. Daniliuc and R. Gilmour, Org. Lett. 2019, 21, 7741-7745. Artwork featured on the front cover

98. Structural and Computational Analysis of 2-Halogeno-Glycosyl Cations in Superacid: An Expansive Platform L. Lebedel, A. Ardá, A. Martin, J. Désiré, A. Mingot, M. Aufiero, N. Aiguabella Font, R. Gilmour, J. Jiménez-Barbero, Y. Blériot, S. Thibaudeau, Angew. Chem. 2019, 131, 13896-13900; Angew. Chem. Int. Ed. 2019, 58, 13758-13762.

97. Fluorinated Analogues of the HDAC Inhibitor Vorinostat (Zolinza®): Validation of a Chiral Hybrid Bioisostere (BITE) N. Erdeljac, K. Bussmann, A. Schöller, F. Hansen and R. Gilmour, ACS Med. Chem. Lett. 2019, 10, 1336-1340. Artwork featured on the front cover

96. Catalytic Vicinal Dichlorination of Unactivated Alkenes J. C. Sarie, J. Neufeld, C. G. Daniliuc and R. Gilmour, ACS Catal. 2019, 9, 7232-7237. Highlighted in C&E News "Dichlorination catalyst eschews chlorine gas"

95. Willgerodt-type Dichloro(aryl)-λ3-Iodanes: A Structural Study J. C. Sarie, J. Neufeld, C. G. Daniliuc and R. Gilmour, Synthesis 2019, 51, 4408-4416. Invited Contribution for the special edition on halogenation (Ed. F. Schoenebeck)

94. Positional and Geometrical Isomerisation of Alkenes: The Pinnacle of Atom Economy J. J. Molloy, T. Morack and R. Gilmour, Angew. Chem. 2019, 131, 13789-13800; Angew. Chem. Int. Ed. 2019, 58, 13654-13664.

93. Inverting Small Molecule-Protein Recognition by the Fluorine Gauche Effect: Selectivity Regulated by Multiple H → F Bioisosterism P. Bentler, K. Bergander, C. G. Daniliuc, C. Mück-Lichtenfeld, R. P. Jumde, A. K. H. Hirsch and R. Gilmour, Angew. Chem. 2019, 131, 11106-11110; Angew. Chem. Int. Ed. 2019, 58, 10990-10994.

92. Stereospecific α-Sialylation by Site-Selective Fluorination T. Hayashi, G. Kehr, K. Bergander and R. Gilmour, Angew. Chem. 2019, 131, 3854-3858; Angew. Chem. Int. Ed. 2019, 58, 3814-3818.

91. Bioinspired Radical Stetter Reaction: Radical Umpolung Enabled by Ion-Pair Photocatalysis T. Morack, C. Mück-Lichtenfeld and R. Gilmour, Angew. Chem. 2019, 131, 1221-1225; Angew. Chem. Int. Ed. 2019, 58, 1208-1212. Artwork featured on the front cover Highlighted in Angewandte Chemie: X. -Yu Chen, D. Enders, Angew. Chem. Int. Ed. 2019, DOI: doi.org/10.1002/anie.201902132.

90. Flavins in Photochemistry J. B. Metternich, R. J. Mudd and R. Gilmour, Science of Synthesis: Photocatalysis in Organic Synthesis, 2019, 391-404. Invited Contribution for the special Science of Synthesis Reference Library: Photocatalysis in Organic Synthesis (Ed. B. König)

2018

88. Enantioselective, Catalytic Vicinal Difluorination of Alkenes F. Scheidt, M. Schäfer, J. C. Sarie, C. G. Daniliuc, J. J. Molloy and R. Gilmour, Angew. Chem. 2018, 130, 16669-16673; Angew. Chem. Int. Ed. 2018, 57, 16431-16435. Highlighted in Synfacts: B. List, D. Diaz-Oviedo, Synfacts 2018, 14, 1299.

87. Exploring Physicochemical Space via a Bioisostere of the Trifluoromethyl and Ethyl Groups (BITE): Attenuating Lipophilicity in Fluorinated Analogues of Gilenya® for Multiple Sclerosis N. Erdeljac, G. Kehr, M. Ahlqvist, L. Knerr and R. Gilmour, Chem. Commun. 2018, 54, 12002-12005. Invited Contribution for the special edition "Organofluorine Chemistry"

85. Informing Molecular Design by Stereoelectronic Theory: The Fluorine Gauche Effect in Catalysis M. Aufiero and R. Gilmour, Acc. Chem. Res. 2018, 51, 1701-1710.

84. Stereocontrolled Synthesis of 2-Fluorinated C-Glycosides A. Sadurni and R. Gilmour, Eur. J. Org. Chem. 2018, 3684-3687. Invited Contribution for the special edition "Organofluorine Chemistry in Europe" Open Access

82. Facial Recognition for Molecules T. Morack and R. Gilmour, Nature 2018, 556, 438-439.

81. Conformational Control Enabled by the Fluorine Gauche Effect in a Model of the β2-AR Agonist Salbutamol (VentolinTM) C. S. Teschers, C. G. Daniliuc, G. Kehr and R. Gilmour, J. Fluorine Chem. 2018, doi.org/10.1016/j.jfluchem.2018.02.007. Invited Contribution for the special edition in memory of Prof. George Olah

 

80. Vitamin Catalysis: Direct, Photocatalytic Synthesis of Benzocoumarins via (–)-Riboflavin-Mediated Electron Transfer T. Morack, J. B. Metternich and R. Gilmour, Org. Lett. 2018, 20, 1316-1319.

 

79. Covalent Immobilization of (–)-Riboflavin on Polymer Functionalized Silica Particles: Application in the Photocatalytic E→Z Isomerization of Polarized Alkenes J. B. Metternich, S. Sagebiel, A. Lückener, S. Lamping, B. J. Ravoo and R. Gilmour, Chem. Eur. J. 2018, 24, 4228-4233. Selected as a "Hot Paper"!

77. Single Site Fluorination of the GM4 Ganglioside Epitope Upregulates Oligodendrocyte Differentiation T. J. Kieser, N. Santschi, L. Nowack, G. Kehr, T. Kuhlmann, S. Albrecht and R. Gilmour, ACS Chemical Neuroscience, 2018, 9, 1159-1165.

76. Spatiotemporal Control of Pre-Existing Alkene Geometry: A Bio-Inspired Route to 4-Trifluoromethyl-2H-Chromenes S. Faßbender, J. B. Metternich and R. Gilmour, Org. Lett. 2018, 20, 724-727.

75. Fluorine-Directed Glycosylation Enables the Stereocontrolled Synthesis of Selective SGLT2 Inhibitors for Type II Diabetes A. Sadurni, G. Kehr, M. Ahlqvist, J. Wernevik, H. Peilot Sjögren, C. Kankkonen, L. Knerr and R. Gilmour, Chem. Eur. J. 2018, 24, 2832-2836. Artwork featured on the front cover Selected as a "Hot Paper"!

74. Harnessing the Maltodextrin Transport Mechanism for Targeted Bacterial Imaging: Structural Requirements for Improved in vivo Stability in Tracer Design A. Axer, S. Hermann, G. Kehr, D. Clases, U. Karst, L. Fischer-Riepe, J. Roth, M. Fobker, M. Schäfers, A. Faust* and R. Gilmour*, ChemMedChem 2018, 13, 241-250. Included in the ChemMedChem Virtual Issue on Antibacterials, available at bit.ly/cmdcantibac18 Artwork featured on the front cover

2017

73. Lewis Base Catalysis in Organic Synthesis. 3 Volume Set. Edited by Edwin Vedejs and Scott E. Denmark (book review)
M. Aufiero, R. Gilmour, Angew. Chem. Int. Ed. 2017, 56, 12045.

72. Deconstructing the Catalytic, Vicinal Difluorination of Alkenes: HF-Free Synthesis and Structural Study of p-TolIF2

Jérôme C. Sarie, Christian Thiehoff, Richard J. Mudd, Constantin G. Daniliuc, Gerald Kehr and Ryan Gilmour, J. Org. Chem. 2017, 82, 11792–11798.

71. Photocatalytic E → Z Isomerization of Polarized Alkenes Inspired by the Visual Cycle: Mechanistic Dichotomy and Origin of Selectivity

Jan B. Metternich, Denis G. Artiukhin, Mareike C. Holland, Maximilian von Bremen-Kühne, Johannes Neugebauer and Ryan Gilmour, J. Org. Chem. 2017, 82, 9955–9977.

70. The Fluorine Gauche Effect: A Brief History
C. Thiehoff, Y. P. Rey, R. Gilmour, Isr. J. Chem. 2017, 57, 92-100.
_{Invited for the "Rosarium Philosophorum on Structural Chemistry", in honour of Prof. Dr. Jack D. Dunitz FRS. Open Access}

69. Quantitative Profiling of the Heavy Atom Effect in BODIPY Dyes: Correlating Initial Rates, Atomic Numbers and 1O2 Quantum Yields
Y. P. Rey, D. G. Abradelo, N. Santschi, C. A. Strassert and R. Gilmour, Eur. J. Org. Chem. 2017, accepted for publication.
_{Invited contribution for the special edition on photocatalysis}

68. Emulating Natural Product Conformation by Cooperative, Non-Covalent Fluorine Interactions
F. Scheidt, P. Selter, N. Santschi, M. C. Holland, D. V. Dudenko, C. Daniliuc, C. Mück-Lichtenfeld, M. R. Hansen and R. Gilmour, Chem. Eur. J. 2017, accepted for publication.
_{Invited contribution for the special edition SFB 858 Münster "Synergistic Effects in Chemistry"}

2016

67. Photocatalytic E → Z Isomerization of Alkenes J. B. Metternich and R. Gilmour, Synlett 2016, 27, 2541-2552.  Invited perspective

66. Catalytic, Vicinal Difluorination of Olefins: Creating a Hybrid, Chiral Bioisostere of the Trifluoromethyl and Ethyl Groups I. G. Molnár, C. Thiehoff, M. C. Holland and R. Gilmour, ACS Catal. 2016, 6, 7167–7173.  Invited contribution

65. The Sulfur-Fluorine Gauche Effect in Coinage Metal Complexes: Augmenting Conformational Equilibria by Complexation N. Santschi, C. Thiehoff, M. C. Holland, C. G. Daniliuc, K. N. Houk and R. Gilmour,  Organometallics 2016, 35, 3040–3044

64. Catalytic Difluorination of Olefins I. G. Molnár and R. Gilmour, J. Am. Chem. Soc. 2016, 138, 5004–5007. This article is featured in JACS spotlight! This work is highlighted in ACS C&E News

63. A “One Photocatalyst, n Activation Modes” Strategy for Cascade Catalysis: Emulating Coumarin Biosynthesis with (–)-Riboflavin J. B. Metternich and R. Gilmour, J. Am. Chem. Soc. 2016, 138, 1040–1045. "This article is featured in JACS spotlight!" "Artwork featured on the front cover" This work is highlighted in ACS C&E News "Highlighted in Synfacts issue 04/2016"

62. Importance of Intermolecular Hydrogen Bonding for the Stereochemical Control of  Allene-Enone (3+2) Annulations Catalyzed by a Bifunctional, Amino Acid Derived Phosphine Catalyst M. C. Holland, R. Gilmour and K. N. Houk, Angew. Chem. Int. Ed. 2016, 128, 2062-2067.

61. Fluorine-Directed 1,2-trans Glycosylation of Rare Sugars N. Aiguabella, M. C. Holland and R. Gilmour, Org. Biomol. Chem. 2016, 14, 5534-5538. Invited contribution for the special New Talent Themed Edition.

60. The Influence of Electronic Perturbations on the Sulfur-Fluorine Gauche Effect C. Thiehoff, L. Schifferer, C. G. Daniliuc, N. Santschi and R. Gilmour, J. Fluorine Chem. 2016, 182, 121-126.

59. Organocatalysis Intermediates as Platforms to Study Non-Covalent Interactions: Integrating Fluorine Gauche Effects in Iminium Systems to Facilitate Acyclic Conformational Control I. G. Molnár, M. C. Holland, C. Daniliuc, K. N. Houk and R. Gilmour, Synlett 2016, 27, 1051–1055. Invited contribution for the Special Cluster Edition on Non-covalent interacts in Catalysis.

2015

57. Medium Ring Effects on the endo/exo Selectivity of the Organocatalytic Intramolecular Diels-Alder Reaction J. F. Hooper, N. C. James, E. Bozkurt, V. Aviyente, J. M. White, M. C. Holland, R. Gilmour, A. B. Holmes and K. N. Houk, J. Org. Chem. 2015, 80, 12058-12075.

54. Synthesis of 2-[18F]Fluoro-2-deoxy-isosorbide-5-mononitrate and Assessment of its in vivo Biodistribution as Determined by Dynamic Positron Emission Tomography (PET) N. Santschi, S. Wagner, C. Daniliuc, S. Hermann, M. Schäfers and R. Gilmour, ChemMedChem 2015, 1724-1732.

53. Delineating the Physical Organic Profile of the 6-Fluoro Glycosyl Donor N. Santschi, N. Aiguabella, V. Lewe and R. Gilmour, J. Fluorine Chem. 2015, 96-101. Invited contribution for the special edition in honour of Prof. V. Gouverneur.

52. Angewandte Chemie Author Profile R. Gilmour, Angew. Chem. Int. Ed. 2015, 54, 11012.

51. Can Acyclic Conformational Control be Achieved via a Sulfur-Fluorine Gauche Effect? C. Thiehoff, M. C. Holland, C. Daniliuc, K. N. Houk and R. Gilmour, Chem. Sci. 2015, 6, 3565-3571.

49. A Janus Cyclohexane Ring N. Santschi and R. Gilmour, Nature Chemistry, 2015, 7, 467-468. (News and Views).

47. Deconstructing Covalent Organocatalysis Reactions M. C. Holland and R. Gilmour, Angew. Chem. 2015, 127, 3934-3943; Angew. Chem. Int. Ed. 2015, 54, 3862-3871.

45. Adsorption and Stability of Chiral Modifiers based on 1-(1-naphthyl)-ethylamine for Pt Catalysed Heterogeneous  Asymmetric Hydrogenations F. Meemken, T. Steiger, M. Holland, R. Gilmour, K. Hungerbühler and A. Baiker, Catal. Sci. Technol. 2015, 5, 705-715.

44. Chiral Imidazolidinone and Proline-Derived Surface Modifiers for the Pt-Catalyzed Asymmetric Hydrogenation of Activated Ketones M. Holland, F. Meemken, A. Baiker and R. Gilmour, J. Mol. Catal. A: Chem. 2015, 396, 335-345.

2014

43. The (not so) Ephemeral Trifluoromethanide Anion N. Santschi and R. Gilmour, Angew. Chem. Int. Ed. 2014, 53, 11414-11415.

42. Infrared Multiphoton Dissociation (IRMPD) Spectroscopic Analysis of Non-Covalent Interactions in Organocatalysis M. C. Holland, G. Berden, J. Oomens, A. J. H. M. Meijer, M. Schäfer and R. Gilmour, Eur. J. Org. Chem. 2014, 26, 5675-5680.

40. Molecular Design Exploiting a Fluorine Gauche Effect as a Stereoelectronic Trigger Y. P. Rey, L. E. Zimmer, C. Sparr, E.-M. Tanzer, W. B. Schweizer, H. M. Senn, S. Lakhdar and R. Gilmour, Eur. J. Org. Chem. 2014, 1202-1211.

39. Enantioselective Aziridination of Cyclic Enals Facilitated by the Fluorine-Iminium Ion Gauche Effect I. G. Molnar, E.-M. Tanzer, C. Daniliuc and R. Gilmour, Chem. Eur. J. 2014, 20, 794-800.

38. The Fluorine Gauche Effect in Molecular Design: A Personal Perspective Y. P. Rey and R. Gilmour, Seminars in Organic Synthesis (book chapter), 2014, 90-98.

2013

37. Modulating NHC Catalysis with Fluorine Y. Rey and R. Gilmour, Beilstein J. Org. Chem. 2013, 9, 2812-2820 *Organofluorine Themed Edition

36. Non-Covalent Interactions in Organocatalysis: Modulating Conformational Diversity and Reactivity in the MacMillan Catalyst. M. C. Holland, S. Paul, W. B. Schweizer, K. Bergander, C. Mück-Lichtenfeld, S. Lakhdar, H. Mayr and R. Gilmour, Angew. Chem. 2013, 125, 8125-8129; Angew. Chem. Int. Ed. 2013, 52, 7967-7971.

35. The Fluorine-NHC Gauche Effect: A Structural and Computational Study. S. Paul, W. B. Schweizer, G. Rugg, H. M. Senn and R. Gilmour, Tetrahedron 2013, 69, 5647-5659.

2012

33. Fluorinated Organocatalysts for the Enantioselective Epoxidation of Enals: Molecular Pre-organisation by the Fluorine-Iminium Ion Gauche Effect. E.-M. Tanzer, L. E. Zimmer, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2012, 18, 11334. Selected as a VIP Paper by the referees.

32. Exploiting Fluorine Conformational Effects in Organocatalyst Design:The Fluorine-Iminium Ion Gauche Effect. C. Sparr, L. E. Zimmer and R. Gilmour, (2011) in Asymmetric Syntheses. More Methods and Applications (Eds. S. Bräse and M. Christmann), Wiley-VCH Verlag GmbH & Co, Weinheim, 117-124.

31. Fluorine-Directed β-Galactosylation: Chemical Glycosylation Development by Molecular Editing. E. Durantie, C. Bucher and R. Gilmour, Chem. Eur. J. 2012, 18, 8208.

30. Fluorinated Cinchona Alkaloids in Phase Transfer Catalysis: Controlling Internal Rotation by a Fluorine-Ammonium Ion Gauche Effect (ØNCCF). E.-M. Tanzer and R. Gilmour, Chem. Eur. J. 2012, 18, 2006.

29. Fundamental Insights into the Enantioselectivity of Hydrogenations on Cinchona-Modified Platinum and Palladium. E. Schmidt, C. Bucher, G. Santarossa, T. Mallat, R. Gilmour and A. Baiker, J. Catal. 2012, 289, 238.

28. d,l-Ribose Crystal Structures: the Glass-Crystal Transformation. G. Zandomeneghi,* W. B. Schweizer,* R. Gilmour,* B. H. Meier,* and J. D. Dunitz,*Helv. Chim. Acta (D. Seebach 75th Birthday Edition) 2012, 95, 1687.

27. The YFM 2012 – Emerging Research and Established Needs: Fund Raising, Publishing and Career Advancement.
B. Winter-Werner, F. Schoenebeck and R. Gilmour, Chimia 2012, 66, 717.

2011

26. Fluorine Conformational Effects in Organocatalysis: An Emerging Strategy for Molecular Design. L. E. Zimmer, C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 12062; Angew. Chem. Int. Ed. 2011, 50, 11860.

25. Cyclopropyl Iminium Activation: Reactivity Umpolung in Enantioselective Organocatalytic Reaction Design. C. Sparr and R. Gilmour, Angew. Chem. 2011, 123, 8541-8545; Angew. Chem. Int. Ed. 2011, 50, 8391-8395. Selected as a Hot Paper  by Angewandte Chemie.

24. Theoretical and X-ray Crystallographic Evidence of a Fluorine-Imine Gauche Effect: An Addendum to Dunathan’s Stereoelectronic Hypothesis. C. Sparr, E. Salamanova, W. B. Schweizer, H. M. Senn and R. Gilmour, Chem. Eur. J. 2011, 17, 8850.

21. Steering Glycosylation with the C-F Bond. C. Bucher and R. Gilmour, Synlett 2011, 1043.

20. A Modular Synthesis of Fluorinated, Chiral Polar Lipids. C. Bucher and R. Gilmour, Synthesis 2011, 549.

2010

19. A Novel Fluorinated Au(I) N-Heterocyclic Carbene Complex: Exploiting Fluorine Stereoelectronic Effects to Control Molecular Topology.
S. Paul, W. B. Schweizer, M.-O. Ebert, and R. Gilmour, Organometallics 2010, 29, 4424.

18. Fluorine-Directed Glycosylation.
C. Bucher and R. Gilmour, Angew. Chem. 2010, 122, 8906; Angew. Chem. Int. Ed. 2010, 49, 8724.

17. Fluoro-Organocatalysts: Conformer Equivalents as a Tool for Mechanistic Studies.
C. Sparr and R. Gilmour, Angew. Chem. 2010, 122, 6670; Angew. Chem. Int. Ed. 2010, 49, 6520.
_{Selected as a Hot Paper by Angewandte Chemie.}

16. A Novel Class of Fluorinated Cinchona Alkaloids as Surface Modifiers for the Heterogeneous Platinum-Catalysed Enantioselective Hydrogenation of α-Ketoesters.
C. Bucher, C. Mondelli, A. Baiker and R. Gilmour, J. Mol. Catal. A: Chem. 2010, 327, 87.

15. The Crystal Structure of D-Ribose – At Last!
D. Šišak, L. B. McCusker, G. Zandomeneghi, B. Meier, D. Bläser, R. Boese, W. B. Schweizer, R. Gilmour and J. D. Dunitz, Angew. Chem. 2010, 122, 4605; Angew. Chem. Int. Ed. 2010, 49, 4503.

14. Stereochemical Models for Discussing Additions to α,β-Unsaturated Aldehydes Organocatalysed by Diarylprolinol or Imidazolidinone Derivatives – is there an E/Z-Dilemma?
D. Seebach,* R. Gilmour,* U. Grošelj, G. Deniau, C. Sparr, M.-O. Ebert and A. K. Beck, Helv. Chim. Acta 2010, 93, 603.

13. A Synthesis of (S)-2-(Fluorodiphenylmethyl)-Pyrrolidine: A Novel Organocatalyst for the Stereoselective Epoxidation of α,β-Unsaturated Aldehydes.
C. Sparr, E.-M. Tanzer, J. Bachmann and R. Gilmour, Synthesis 2010, 1394.

2009

12. Fluorinated Quinine Alkaloids: Synthesis, X-ray Structure Analysis and Anti- Malarial Parasite Chemotherapy.
C. Bucher, C. Sparr, W. B. Schweizer and R. Gilmour, Chem. Eur. J. 2009, 15, 7637.

11. The Fluorine-Iminium Ion Gauche Effect: Proof of Principle and Application to Asymmetric Organocatalysis.
C. Sparr, W. B. Schweizer, H. M. Senn and R. Gilmour, Angew. Chem. 2009, 121, 3111; Angew. Chem. Int. Ed. 2009, 48, 3065.

10. Total Syntheses of Amphidinolides B1, B4, G1, H1 and Structural Revision of Amphidinolide H2.
A. Fürstner, L. C. Bouchez, L. Morency, J.-A. Funel, V. Liepins, F.-H. Poree, R. Gilmour, D. Laurich, F. Beaufils and M. Tamiya, Chem. Eur. J. 2009, 15, 3983.

9. The Handbook of Chemical Glycosylation: Advances in Stereoselectivity and Therapeutic Relevance.
R. Gilmour and P. H. Seeberger, J. Am. Chem. Soc. 2008, 130, 11241.

8. Fast and Efficient Radical Based-Reduction and Hydrosilylation Reactions in a Microreactor Using Tris(Trimethylsilyl)silane.
A. Odedra, K. Geyer, T. Gustafsson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3025.

7. Fluorination Reactions made Safe by Microreactors.
T. Gustaffson, R. Gilmour and P. H. Seeberger, Chem. Commun. 2008, 3022.

6. The Development of a High-Throughput, Microarray-Based Synthesis of Natural Product Analogues via in Vitro Pathway Construction.
R. Gilmour and P. H. Seeberger, ChemTracts-Organic Chemistry 2007, 191.

5. Structural Diversity in Imidazolidinone Organocatalysts: A Synchrotron and Computational Study.
J. C. Burley, R. Gilmour, T. J. Prior and G. M. Day, Acta Cryst. 2008, C64, o10.

4. The Total Synthesis of Amphidinolide H and G.
A. Fürstner, L. C. Bouchez, J. -A. Funel, V. Liepins, F.–H. Porée, R. Gilmour, F. Beaufils, D. Laurich and M. Tamiya, Angew. Chem. 2007, 119, 9425; Angew. Chem. Int. Ed. 2007, 46, 9265.

3. An Organocatalytic Approach to the Core of Eunicellin.
R. Gilmour, T. J. Prior, J. W. Burton and A. B. Holmes, Chem. Commun. 2007, 3954.

2. The Synthesis and Biological Evaluation of Novel Eunicellin Analogues.
J. E. P. Davidson, R. Gilmour, S. Ducki, J. E. Davies, R. Green, J. W. Burton and A. B. Holmes, Synlett 2004, 8, 1434.

1. Synthetic Studies Related to Diketopyrrolopyrrole (DPP) Pigments. Part 1: The Search for Alkenyl DPPs. Unsaturated Nitriles in Standard DPP Syntheses: A Novel Cyclopenta[c]pyrrolone Chromophore.
J. H. Morton, R. Gilmour, D. M. Smith, P. Lightfoot, A. M. Z. Slawin, and E. J. MacLean, Tetrahedron 2002, 58, 5547.