Priv. Doz. Dr. Nermin Seda Kehr
Curriculum Vitae
Feb. 02th 2022 The National Scientific Qualification as Full Professor in Bioengineering
The Ministry of Education, University and Research, ItalyApr. 15th 2021 Venia Legendi in Organic Chemistry
University of MünsterSince July. 2015 Independent group leader (DFG-temporary position)
University of Münster/Institute of Physics and Center for Soft Nanoscience (SoN), GermanySep. 2018 - Dec. 2018 Invited Visiting scientist
Research group of Prof. Khademhosseini, University of California, Los Angeles (UCLA), USAJune 2014 - July 2015 Senior scientist
Research group of Prof. Fuchs, University of Münster/Institute of Physics, GermanyMar. 2013 – May. 2014 Senior scientist
Research group of Prof. Galla, University of Münster/Instiute of Biochemistry, GermanyJun. 2011 - Aug. 2011 Visiting scientist
Research group of Prof. Langer, Massachusetts Institute of Technology, USAOct. 2012 – Feb. 2013 Senior scientist
Research group of Prof. De Cola, University of Strasbourg/Institut de Science et d'Ingénierie Supramoléculaires, FranceJan. 2009 – Sep. 2012 Senior scientist
Research group of Prof. De Cola, University of Münster/Institute of Physics, GermanyJan. 2008 – Dec. 2008 Postdoctoral researcher
Research group of Prof. De Cola, University of Münster/Institute of Physics, GermanyJan. 2007 - Dec. 2007 Postdoctoral researcher
Research group of Prof. Ravoo, University of Münster/Institute of Organic Chemistry, GermanySept. 2006 - Dec. 2006 Postdoctoral researcher
Department of Mass spectrometry, University of Münster/Institute of Organic Chemistry, Germany2003 - 2005 PhD Education
University of Münster/Institute of Organic Chemistry, Germany; Supervisor: Prof. Dieter Hoppe
“(-)-Sparteine-Induced Enantioselective Homoaldol Reactions and Their Applications”July 14th, 2005 Promotion: Doktor der Naturwissenschaft (magna cum laude)
Publications
3D-Printed Oxygen-Carrying Nanocomposite Hydrogels for Enhanced Cell Viability under Hypox-ic and Normoxic Conditions
Motealleh A, Schäfer A. H ,Fromm O, Kehr N. S.Biomacromolecules, 2021, doi.org/10.1021/acs.biomac.1c01067
Functional Nanomaterials and 3D-Printable Nanocomposite Hydrogels for Enhanced Cell Proliferation and for the Reduction of Bacterial Biofilm Formation
Motealleh A, Kart D, Czieborowski M, Kehr N. S.
ACS Appl. Mater. Interfaces 2021, 13, 437553D Printed Step-gradient Composite Hydrogels for Directed Migration and Osteogenic Differentiation of Human Bone Marrow-derived Mesenchymal Stem Cells
Motealleh A, Schulten A, Kehr N. S.
Nano Select, 2021, DOI: 10.1002/nano.202100113Step-gradient Composite Hydrogels for Local Drug Delivery and Directed Cell Migration
Motealleh A, Kehr N. S.
Adv. NanoBiomed Res. 1, 2021, 202000114Bifunctional nanomaterials for simultaneously improving cell adhesion and affecting bacterial biofilm formation on silicon-based surfaces
Motealleh A, Dorri P, Czieborowski M, Philipp B, Kehr N. S.
Biomed. Mater., 2021, 16, 025013Recent Advances in Injectable Hydrogels for Controlled and Local Drug Delivery
Rizzo F, Kehr N. S.
Adv. Healthcare Mater. 2021, 2001341Directed Vertical Cell Migration via Bifunctionalized Nanomaterials in 3D Step-gradient Nanocomposite Hydrogels
Motealleh A, Kehr N. S.
Biomater. Sci., 2020, 8, 5628Injectable oxygen-generating nanocomposite hydrogels with prolonged oxygen delivery for enhanced cell proliferation under hypoxic and normoxic conditions Motealleh A, Kehr N. S.
J. Mater. Chem. B., 2020, 8, 4195-4201Injectable Polymer/Nanomaterial Composites for the Fabrication of Three-Dimensional Biomaterial Scaffolds
Motealleh A, Dorri P, Kehr N. S.
Biomed. Mater, 2020, 15, 045021Bifunctional Nanomaterials for Enhanced Cell Proliferation and for the Reduction of Bacterial Bioluminescence/Fitness
Motealleh A, Czieborowski M, Philipp B, Nowak S, Kehr N. S.
Adv. Mater. Interfaces, 2020, 7, 2000086.Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels for Enhanced Cell Adhesion in 3D Hydrogel Network
Kehr N. S.
Journal of Applied Biological Sciences, 2019, 13, 133-137Functional Nanomaterials on 2D Surfaces and in 3D Nanocomposite Hydrogels for Biomedical Applications
Tutar R, Motealleh A, Khademhosseini A, Kehr N. S.
Adv. Func. Mater, 2019, 19043443D Printing of Step-Gradient Nanocomposite Hydrogels for Controlled Cell Migration
Motealleh A, Celebi-Saltik B, Ermis N, Nowak S, Khademhosseini A, Kehr N. S
Biofabrication, 2019, 11, 045015Self Assembled Monolayers of Chiral Periodic Mesoporous Organosilica as Stimuli Responsive Local Drug Delivery System
Motealleh A, Dorri P, Kehr N.S.
J. Mater. Chem. B., 2019, 7, 2362-2371Advances in Controlled Oxygen-Generating Biomaterials for Tissue Engineering and Regenerative Therapy
Ashammakhi N, Darabi M, Kehr N.S., Erdem A, Shau-Kai Hu, Dokmeci M, Nasr A, Khademhosseini A
Biomacromolecules, 2019, 11, 56.Stimuli-responsive Local Drug Molecule Delivery to Adhered Cells in a 3D Nanocomposite Scaffold
Motealleh A, de Marco R, Kehr N.S.
J. Mater. Chem. B., 2019, 7, 3716-37233D Bioprinting of Triphasic Nanocomposite Hydrogels and Scaffolds for Cell Adhesion and Migration
A. Motealleh, P. Dorri, A. H. Schäfer, and N. S. Kehr
Biofabrication, 2019, 32, 035022Chirality-Dependent Cell Adhesion and Enrichment in Janus Nanocomposite Hydrogels
Motealleh A, Hermes H, Jose J, Kehr N.S.
Nanomedicine 2018, 14, 247 - 256Highly fluorescent water soluble spirobifluorene dye with large Stokes shift: synthesis, characterization and bio-applications
Schlüter F, Riehemann K, Kehr N.S., Quici S, Daniliuc C.G., Rizzo F
Chem. Commun. 2018, 54, 642 - 645Janus Nanocomposite Hydrogels for Chirality-Dependent Cell Adhesion and Migration
Motealleh A, Kehr N.S.
ACS Appl. Mater. Interfaces. 2017, 9, 33674 – 33682Janus Enantiomorphous Nanomaterial Assembly on Substrate Surfaces for Chirality-Dependent Cell Adhesion
Kehr N.S.
Colloids Surf. B, 2017, 159, 125Chirality-Dependent Cellular Uptake of Chiral Nanocarriers and Intracellular Delivery of Different Amounts of Guest Molecules
Kehr N.S., Jose J
Appl. Surf. Sci. 2017, 425, 432 – 439Nanocomposite (Janus) paper as 3D cell culture system
Kehr N.S., Motealleh A
Colloids Surf. B, 2017, 156, 236 – 242Microcontact Printing of (Bio)Molecules on Self-Assembled Monolayers of Zeolites L and Surface Mediated Drug Delivery
Kehr N.S.
Adv. Porous Mater. 2017, 5, 1 – 9Nanocomposite Hydrogels and Their Applications in Tissue Engineering
Motealleh A, Kehr N.S.
Adv. Healthcare Mater. 2017, 6, 16009388 (invited review article)Cell Growth on “Janus” Density Gradients of Bifunctional Zeolites
Kehr N.S., Motealleh A, Schäfer A.H.
ACS Appl. Mater. Interfaces. 2016, 8, 35081 – 35090Surface Mediated Stimuli Responsive Organic Molecules Delivery from Porous Carrier to Adhered Cells
Ergün B, De Cola L, Galla H.-J., Kehr N.S.
Adv. Healthcare Mater. 2016, 5, 1588 – 1592Enantiomorphous Periodic Mesoporous Organosilica based Nanocomposite Hydrogel Scaffolds for Cell Adhesion and Cell Enrichment
Kehr N.S.
Biomacromolecules, 2016, 17, 1117 – 1122Controlled Cell Growth and Cell Migration in PMOs/Alginate Nanocomposite Hydrogels
Kehr N.S., Riehemann K
Adv. Healthcare Mater. 2016, 5, 193 – 197Self-assembled monolayers of enantiomerically functionalized periodic mesoporous organosilicas and the effect of surface chirality on cell ladhesion
behaviour
Kehr N.S., Galla H.-J., Riehemann K, Fuchs H
RSC Adv. 2015, 5, 5704 – 5710Self-assembled Monolayers and Nanocomposite Hydrogels of Functional Nanomaterials for Tissue Engineering Applications
Kehr N.S., Atay S, Ergün B
Macromol. Biosci. 2015, 15, 445 – 463 (invited review article)Spatial controlled channel entrances functionalisation of zeolites L
Kehr N.S., Ergün B, Lülf H, De Cola L
Adv. Mater, 2014, 26, 3248 − 3252Cell adhesion behaviour in 3D hydrogel scaffolds functionalized with D- or L-aminoacids
Benson K, Galla H.-J., Kehr N.S.
Macromol. Biosci. 2014, 14, 793 − 798When self-assembly meets biology: luminescent platinum complexes for imaging applications
Mauro M, Aliprandi A, Septiadi D, Kehr N.S., De Cola L
Chem Soc. Rev. 2014, 43, 4144 − 4166Fluorescent Modular Boron Systems Based on NNN- and ONO-Tridentate Ligands: Self-Assembly and Cell Imaging
C. Glotzbach, U. Kauscher, J. Voskuhl, N. S. Kehr, M. C. A. Stuart, R. Fröhlich, H. J. Galla, B. J. Ravoo, K. Nagura K, Saito S, Yamaguchi S, Würthwein E.-U.
J. Org. Chem. 2013, 78, 4410 − 4418Periodic Mesoporous Organosilica-Based Nanocomposite Hydrogels as Three-Dimensional Scaffolds
Kehr N.S., Prasetyanto E.A., Benson K, Ergün B, Galstyan A., Galla H.-J.
Angew. Chem. Int. Ed., 2013, 52, 1156 - 1160Bifunctional periodic mesoporous organosilicas and their self-assembled monolayers as biocompatible surfaces
Benson K, Prasetyanto Y.E.A., Galla H.-J., Kehr N.S.
Soft Matter, 2012, 5, 10845 - 10852Power Struggles between oligopeptides and Cyclodextrin Vesicles
Versluis F, Voskuhl J, Stuart M.C.A., Kehr N.S., Ravoo B.J., Kros A
Soft Matter, 2012, 8, 8770 - 8777Dendrimer-Modified Solid Supports: Nanostructured Materials with Potential Drug Allergy Diagnostic Applications
Ruiz-Sanchez A.J., Montañez M.I., Mayorga C, Torres M.J., Kehr N.S., Vida Y, Collado D, Najera F, De Cola L, Perez-Inestrosa E
Current Medical Chem., 2012, 19, 4952 - 4954Melanin-like Hydrogels Derived From Gallic Macromers
O. Z. Fisher, B. L. Larson, D. Graupner, M. T. Nguyen-Kim, N. S. Kehr, L. De Cola, R. Langer*, D. G. Anderson
Adv. Mater. 2012, 24, 3032-3036Cell Adhesion Behaviour on Enantiomerically Functionalized Zeolite L Monolayers
El-Gindi J, Benson K, De Cola L, Galla H.-J., Kehr N.S.
Angew. Chem. Int. Ed., 2012, 51, 3716-3720Click Chemistry on Self-assembled Monolayer of Zeolite L Crystals by Microcontact Printing - Applications in Nanobiotechnology
Kehr N.S., El-Gindi J, Galla H.-J., De Cola L
Mic. Mes. Mater., 2011, 144, 9-14Cell Adhesion and Cellular Patterning on a Self-Assembled Monolayer of Zeolite L Crystals
Kehr N.S., Riehemann K, El-Gindi J, Schäfer A, Fuchs H, Galla H.-J., De Cola L
Adv. Funct. Mater., 2010, 20, 2248-2254Asymmetric printing of molecules and zeolites on self assembled monolayers
Kehr N.S., Schäfer A, Ravoo B.J., De Cola L
Nanoscale, 2010, 2, 601–605Shape and Release Control of a Peptide Decorated Vesicle through pH Sensitive Orthogonal Supramolecular Interactions
Verluis F, Tomatsu I, Kehr N.S., Fregonese C, Stuart M, Ravoo B.J., Koning R, Kros A
J. Am. Chem. Soc., 2009, 131, 13186–13187(N-Arylaminomethyl)pyridine-N-oxides: Synthesis and characterization of potential ligand systems and the formation of their N,O-chelate aluminum complexes
Nienkemper K, Kehr G, Kehr N.S., Fröhlich R, Erker G
J. Org. Chem., 2008, 18, 3063- 3073Functionalized phosphorus analogues of the β-diketiminato ligand systems: bis(N-arylphosphinimino)acetonitrile-derived complexes of rhodium and iridium
Spannoff K, Kehr G, Kehr N.S., Fröhlich R, Erker G
Dalton Trans., 2008, 25, 3339-3344(Amidomethyl)pyridine zirconium and hafnium complexes: Synthesis and structural characterization
Nienkemper K, Kehr G, Kehr N.S., Fröhlich R, Erker G
J. Org. Chem., 2008, 693, 1572-1589Highly enantioselective reactions of configurationally labile epimeric diamine complexes of lithiated S-benzyl thiocarbamates
Lange H, Bergander K, Fröhlich R, Kehr N.S., Nakamura S, Shibata N, Toru T, Hoppe D
Chem. Asian J., 2008, 3, 88-101Formation and Structural and Dynamic Features of Atropisomeric η2-Iminoacyl Zirconium Complexes
Spies P, Kehr G, Kehr N.S., Fröhlich R, Erker G
Organometallics, 2007, 26, 5612-5620Polymer characterization by electrospray-mass-spectrometry - shifting the upper mass limit
Kehr N.S., Luftmann H
e-Polymers, 2007, 10Synthesis of enantioenriched and diastereomerically pure cis-fused bicyclic α-oxy-substituted γ-lactones via epoxidation of optically active homoaldol products
Ünaldi N.S., Fröhlich R, Hoppe D
Synthesis, 2005, 15, 2507−2520Enantio- and diastereoselective synthesis of highly substituted acylcyclopropanes from homoaldol products by stereospecific homoallylic cyclization
Kalkoven R, Brandau S, Ünaldi N.S., Fröhlich R, Hoppe D
Eur. J. Org. Chem., 2005, 21, 4571−4580Diastereoselective synthesis of enantioenriched, annulated tetrahydrofurans by simultaneous formation of the O-1-C-5 and the C-5-C-4 bonds
Ünaldi S, Özlügedik M, Fröhlich R, Hoppe D
Adv. Synth. Cat., 2005, 347, 1621−1626Synthesis of enantioenriched trans-fused bicyclo[4.4.0]-dec-3-enes and bicyclo[4.3.0]non-3-enes bearing a 1,5-lactone bridge
Özlügedik M, Ünaldi S, Wibbeling B, Hoppe D
Adv. Synth. Cat., 2005, 347, 1627−1631Organic synthesis via transition metal complexes, part 120. C-C insertion: Insertion of an alkyne into the C-C single bond between the carbene-carbon atom and the π - carbon atom of a Fischer carbene complex by an unprecedented metalla(di-π-methane) skeletal rearrangement
Ünaldi S, Fröhlich R, Aumann R
Chem. Eur. J., 2003, 9, 3000-3009The di-π-methane photorearrangement of 2,3-Disubstituted benzobarrelenes and benzonorbornadiene - substituent effects in regioselectivity
R. Altundas, A. Dastan, S. Ünaldi, K. Guven, O. Uzun, M. Balci
Eur. J. Org. Chem., 2002, 3, 526-533Substituent effect on regioselectivity in the di-π-methane rearrangement: synthesis of disubstituted benzobarrelene derivatives and their photochemistry
Ünaldi S, M. Balci M
Tetrahedron Lett., 2001, 42, 8365-8367
Teaching
Teaching
PolyNano Seminar (Master degree course), University of Münster, Germany (2021)
Grundlagen-Modul-Chemie, Theoretische Übungen zum Organisch-Chemischen Kurs für Biowissenschaftler, (Barchelor degree course), University of Münster, Germany (2020)
Grundlagen-Modul-Chemie, Theoretische Übungen zum Organisch-Chemischen Kurs für Biowissenschaftler, (Barchelor degree course), University of Münster, Germany (2019)
Praktikum OC-II, Lehramt Chemie, (Barchelor degree course), University of Münster, Germany (2019)
Polymers, (Master degree course), University of Münster, Germany (2019)
Seminar zum Chemischen Praktikum OC-IIb, Lehramt Chemie, (Barchelor degree course), University of Münster, Germany (2019)
Theoretical Exercises of the Organic Chemistry Course for Biosciences (Barchelordegree course), University of Münster, Germany (2018)
Chemistry Training Seminar (Barchelor degree course), University of Münster, Germany (2018)
PolyNano Course, (Master degree course), University of Münster Germany (2018)
PolyNano Course, (Master degree course), University of Münster German (2017)
PolyNano Seminar (Master degree course), University of Münster, Germany (2017)
Chemistry Training Seminar (Barchelor degree course), University of Münster, Germany (2017)
PolyNano Course, (Master degree course), University of Münster Germany (2016)
PolyNano Seminar (Master degree course), University of Münster, Germany (2016)
Biochemistry I, (Barchelor degree course), University of Münster Germany (2013)
General Aspects of Nanoparticles (Master degree course), University of Münster, Germany (2011-2013)
Structure of Materials (Barchelor degree course), University of Münster, Germany (2010-2012)
Invited lectures and conferences
Invited lectures and conferences
- Tissue Engineering and Regenerative Medicine International Society, the Nederlands (Nov. 2021):“3D Printing of Nanocomposite Hydrogels/Polymers for Local Drug Delivery Applications”
- 9th NRW Nano Conference, Germany (Apr. 2021): Oral presentation
“Injectable Nanocomposite Hydrogels/Polymers for Local Drug Delivery Applications” - Milan Polymer Days, (Jul 2020): “Injectable nanocomposite hydrogels for controlled cell migration and local drug delivery applications”
- Sixth International Conference on Multifunctional, Hybrid and Nanomaterials, Spain, (Mar. 2019):"Janus, Triphasic, and Step-Gradient Nanocomposite Hydrogels for Controlled Cell Migration in 3D Network
- Rimini Peptides, Italy (Jun. 2018): “Nanomaterials for cell-material interaction studies”.
- Frontier Forum Meeting on NanoSciences, Croatia (May. 2017): “Arrays and Nanocomposite Hydrogels of Bifunctional Nanomaterials for Biomedical Applications”.
- 29th Deutsche Zeolith-Tagung, Germany (Mar. 2017): “Bifunctional Zeolite L for Biomedical Applications”.
Max Planck Institute of Colloids and Interfaces, Germany (Dec. 2016): “Cell-Material Interaction and Surface Mediated Controlled Drug Delivery”.
University of Bologna, Italy (Feb. 2016): “Cell adhesion on self-assembled monolayers and nanocomposite hydrogels of functional porous nanomaterials”. - 2nd International Symposium on Nanoparticles/Nanomaterials and Applications, Portugal (Jan. 2016): “Self-assembled monolayers and nanocomposite hydrogels of enantiomorphous porous nanomaterials”.
- Santa Barbara State University of California, USA (Feb. 2014): “Cell adhesion on functionalized 2D surfaces or in 3D scaffolds”.
- Bilkent University, Turkey (May. 2013): “Functional porous nanoparticles for the generation of 2D surfaces and 3D scaffolds”.
- TOBB University of Economics and Technology, Turkey (May 2013): “Generation of new 2D surfaces and 3D scaffolds”.
- Tübitak Marmara research Center, Turkey (May 2013): “Functional porous nanoparticles and their applications”.
- University of Jyväskylä and Aalto University, Finland (Nov.2012 ): “Functional porous nanoparticles for the generation of 2D surfaces and 3D scaffolds”.
- University of Helsinki, Finland (Apr. 2012): “Silica based functional porous nanoparticles for biotechnological applications”.
- Santa Barbara State University of California, USA (Feb. 2012): “Functional periodic mesoporous organosilicas as biocompatible surfaces”.
- University of Toronto, Canada (Feb. 2012): ”Periodic mesoporous organosilica based materials for biotechnological applications”.
- University of Nagoya, Japan (May. 2010): “Functionalization of Zeolite L Monolayers by Microcontact Chemistry and Their Application in Biotechnology”.
- Santa Barbara State University of California, USA (Feb. 2010): “Functionalization of Zeolite L Nanocrystals by Microcontact Printing and Interaction of Zeolite L Nanocrystals with Biological Systems”.
- University of Münster, Germany (Jul. 2009): “Interaction of Zeolite L Nanocrystals with Living Systems”.
- Emory University, Atlanta, USA (Mar. 2009): “Interaction of Zeolite L Nanocrystals with Living Systems”.
- Santa Barbara State University of California, USA (Mar. 2009): “Zeolite L Nanocrystals and Living Systems”.
- Emory University, Atlanta, USA (Mar. 2008): “Synthesis of Amphiphilic Cyclodextrins and Recognization of Guest Molecules in Water”.
- University of Toronto, Canada (Mar. 2008): “Formation of Bilayer Vesicles from Amphiphilic Cyclodextrins and Recogniztion of Guest Molecules in Water”.
- Santa Barbara State University of California, USA (Mar. 2008): “Host-Guest interaction of Amphiphilic Cyclodextrin Vesicles and Guest Molecules in Water”.
- University of Winsor, Ontario, Canada (Feb. 2007): “New Approach to Polymer Characterization by Electrospray-Mass Spectrometry”.
Santa Barbara State University of California, USA (Feb. 2007): “Polymer Characterization by Electrospray-Mass Spectrometry-Shifting the Upper Mass Limit”. - Santa Barbara State University of California, USA (Feb. 2005): “Synthesis of Nonracemic, Chiral Homoenolate Reagents and Their Applications”.