Institute of Medical Psychology and Systems Neuroscience
48149 Münster
jana.harenbrock@uni-muenster.de
Joined OCC in 2024
Joined OCC in 2024
My dissertation is embedded in a DFG-funded project on mechanisms of deviance processing.
Experimentally, deviance processing can be investigated by using oddball paradigms. In these paradigms, a rare deviant stimulus is presented interspersed in a frequent stream of standard stimuli. When comparing neural activity elicited by the deviant to the standard stimulus, deviance-related increased brain responses are observed, namely the mismatch negativity (MMN) and the P3. On a mechanistic level, the framework of predictive processing explains this higher activity for deviant stimuli via a mismatch of expectations and sensory input. The deviant stimulus is unexpected compared to the standard and does thus elicit a higher prediction error. A competing approach is the adaptation hypothesis. This framework states that MMN can be explained by refractoriness of neural populations towards the standard stimulus. Previously non-adapted neurons respond once the deviant stimulus is presented, eliciting an N1. Therefore, the adaptation hypothesis states that the MMN is part of a modulated N1. It is widely accepted that MMN is generated partly by both, adaptation and prediction mechanisms and recent studies have shown that the extent of prediction and adaptation mechanisms vary with manipulating task-relevance and awareness as well as with the hierarchical processing level. However, it is unclear if the contribution of both mechanisms varies systematically. Further, the spatiotemporal generation process of MMN and which variables moderate this process is largely unknown. I aim to investigate the spatiotemporal generation process of MMN and to which extent prediction and adaptation contribute in generating MMN using EEG, fMRI and neurocomputational modeling.
Prof. Dr. Thomas Straube
Dr. Insa Aschlßmacher
Apl. Prof. Dr. Jens Bölte
Agus Khorisantono, P., Fondberg, R., Lundström, J. N., Seubert, J., Achs, L., Friedrich, N. N., Harenbrock, J., Hog, L., Persson, J., & Weber, M.-C. (2024). Dissociable effects of hunger, exposure and sensory overlap on flavour liking. Food Quality and Preference, 105211. https://doi.org/10.1016/j.foodqual.2024.105211
Harenbrock, J., Forthmann, B., & Holling, H. (2023). Retest Reliability of Situational Judgment Tests. Journal of Personnel Psychology, 22(4), 169–184. https://doi.org/10.1027/1866-5888/a000323
Harenbrock, J., Holling, H., Reid, G., & Koychev, I. (2023). A meta-analysis of the relationship between sleep and β-Amyloid biomarkers in Alzheimer’s disease. Biomarkers in Neuropsychiatry, 9, 100068. https://doi.org/10.1016/j.bionps.2023.100068
Schrammen, E., Roesmann, K., Rosenbaum, D., Redlich, R., Harenbrock, J., Dannlowski, U., & Leehr, E. J. (2022). Functional neural changes associated with psychotherapy in anxiety disorders – A meta-analysis of longitudinal fMRI studies. Neuroscience & Biobehavioral Reviews, 142, 104895. https://doi.org/10.1016/j.neubiorev.2022.104895
Harenbrock, J., Dellert, T., Straube, T., & Schloßmacher, I. (2024). Differential auditory mismatch responses depending on awareness and task relevance. Talk at the 49th Annual Meeting “Psychologie und Gehirn”, Hamburg, Germany.
Harenbrock, J., Kambestad, O., Holling, H., Nordhus, I. H., Visted, E., Sørensen, L., Osnes, B., Bjerrum, L., Jansen, K., Flo-Groeneboom, E. (2023). The acute effects of different light modalities on alertness and cognitive performance: A systematic review and meta-analysis. Talk at the eSleep Europe Virtual Congress 2023.
*1999 | Münster, Germany |
2017-2020 | Bachelor studies in Psychology at the University of Münster, Germany |
2020-2023 |
Master studies in Psychology with specialization in Cognitive Neurosciences at the University of Münster, Germany |
2019-2022 |
Student Assistant at the Department of Statistics and Methods, Institute of Psychology, University of Münster |
since 2023 |
Beginning of PhD research project at the Institute of Medical Psychology and Systems Neuroscience, University of Münster |