Professor Dr. Joachim Jose
Professur für Pharmazeutische Chemie (Prof. Jose)

Corrensstr. 48

 

  • Research Areas

    • Assay development and inhibitor testing
    • Whole cell biocatalysts for synthesis of drugs and building blocks
    • Directed evolution of enzyme inhibitors and biocatalysts
    • Biosensor development and diagnostic tools

  • Further Affiliation at the University of Münster

  • CV

    Education

    Habilitation and venia legendi in Pharmaceutical and Medicinal Chemistry.
    Thesis, “Structure and reaction mechanism of urease from St. xylosus”, Promotion to a Dr. rer. nat.
    Diploma in Biology (main subjects: microbiology, genetics, biochemistry) at the University of Saarbrücken and research assistant in the Department of Microbiology.

    Positions

    Full Professor (W3) and Chair for Pharmaceutical and Medicinal Chemistry at Westfälische Wilhelms-University, Münster
    Head of the Institute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University, Düsseldorf
    Associate Professor (C3) in Bioanalytics at the Institute of Pharmaceutical and Medicinal Chemistry, Heinrich-Heine-University, Düsseldorf
    Co-founder of the Start-up Company Autodisplay Biotech GmbH, for biocatalytic synthesis and evolutive drug design. http://www.autodisplay-biotech.com
    Assistant Professor (C1) at Saarland University, Saarbrücken
    Co-founder of the Start-up company Pharmacelcus GmbH, CRO Drug Absorption Screening. http://www.pharmacelsus.com Founding member of the center for Bioinformatics (ZBI), member of the ZBI council (2000–2005). http://www.zbi.uni-saarland.de/
    Senior Researcher in the group of Prof. Rolf W. Hartmann in the Department of Pharmaceutical and Medicinal Chemistry, Saarland University, Saarbrücken
    Post-Doc in the group of Prof. Thomas F. Meyer at the Max-Planck-Institute for Biology, Tübingen, Department of Infection Biology, and at the MPI for Infection Biology, Berlin, Department Molecular Genetics.

    Honors

    Best presentation award – 1st International Electronic Conference on Medicinal Chemistry
    Best Flash Presentation Prize of TTMC 2015 – 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015
    Poster prize – Forschung der Chemischen Industrie (Symposium)
    Poster prize – European Congress of Biotechnology
    Medaille der Fakultät für Biologie und Pharmazie der Universität Claude Bernard, Lyon – Universität Claude Bernard, Lyon
    Korrespondierendes Mitglied der French National Academy of Pharmacy – French National Academy of Pharmacy
    1st prize of the DPhG Doktorandentagung – DPhG Doktorandentagung
    Wissenschaftspreis der SaarLB 2004 – SaarLB & Ministerium für Wirtschaft und Wissenschaft des Saarlandes
    Posterpreis – GDCh Fachgruppe Medizinische Chemie
    Poster prize – DPhG Jahrestagung
    Innovationspreis 1998 – Fachgruppe Medizinische Chemie der GdCH und Fachgruppe Pharmazeutische Chemie der DPhG

    External Function

    Gesellschaft für Biochemie und Molekularbiologie (GBM, previously GBCH) Vereinigung für Allgemeine und Angewandte Mikrobiologie (VAAM) Deutsche Pharmazeutische Gesellschaft (DPhG) Gesellschaft für Chemische Technik und Biotechnologie (DECHEMA) American Society for Microbiology (ASM)

  • Projects

    In Process
    Finished

  • Publications

    • Gercke D, Lenz F & Jose J. (). Split-GFP complementation at the bacterial cell surface for antibody-free labeling and quantification of heterologous protein display. Enzyme and Microbial Technology, 174. doi: 10.1016/j.enzmictec.2023.110391.
    • Saenger T, Schulte MF, Vordenbäumen S, Herrmann FC, Bertelsbeck J, Meier K, Bleck E, Schneider M & Jose J. (). Structural Analysis of Breast-Milk αS1-Casein: An α-Helical Conformation Is Required for TLR4-Stimulation. International Journal of Molecular Sciences, 25. doi: 10.3390/ijms25031743.
    • Sung JS, Kim S, Jung J, Kim T-H, Kwon S, Bae HE, Kang M-J, Jose J, Lee M & Pyun J-C. (). Monoamine Oxidase-A (MAO-A) Inhibitors Screened from the Autodisplayed Fv-Antibody Library. ACS Pharmacology and Translational Science, 7. doi: 10.1021/acsptsci.3c00204.
    • Bong J-H, Dombovski A, Birus R, Cho S, Lee M, Pyun J-C & Jose J. (). Covalent coupling of functionalized outer membrane vesicles (OMVs) to gold nanoparticles. Journal of Colloid and Interface Science, 663. doi: https://doi.org/10.1016/j.jcis.2024.02.137.
    • Sung JS, Han Y, Yun TG, Jung J, Kim T-H, Piccinini F, Kang M-J, Jose J, Lee M, Pyun J-C . (). Monocarboxylate transporter-1 (MCT-1) inhibitors screened from autodisplayed FV-antibody library. International Journal of Biological Macromolecules, 265. doi: 10.1016/j.ijbiomac.2024.130854.
    • Gesing Katrin, Lenz Florian, Schreiber Sebastian, Kasimir Matthias, Humpf Hans-Ulrich, Jose Joachim. (). Surface Display and Engineering of Laccase CotA for Increased Growth of Pseudomonas putida on Lignin. ChemCatChem, 16(4). doi: 10.1002/cctc.202301055.

    • Goracci L, Nurisso A, Roussel E, Pérès B, Chaptal V, Falson P, Marminon C, Jose J, Le Borgne M & Boumendjel A. (). Inhibitors of ABCG2-mediated multidrug resistance: Lead generation through computer-aided drug design. European Journal of Medicinal Chemistry, 248. doi: 10.1016/j.ejmech.2022.115070.
    • Nickelsen Anna, Götz Claudia, Lenz Florian, Niefind Karsten, König Simone, Jose Joachim,. (). Analyzing the interactome of human CK2β in prostate carcinoma cells reveals HSP70-1 and Rho guanin nucleotide exchange factor 12 as novel interaction partners. FASEB BioAdvances, 00, 1–17. doi: 10.1096/fba.2022-00098.
    • Kim Seong Gi, Kim JeeYoung, Kim Mi Yeon, Park Jong-Min, Jose Joachim, Park Min,. (). Autodisplay of streptococcal protein G for construction of an orientation-controlled immunoaffinity layer. Analyst, 148. doi: 10.1039/D2AN01753A.
    • Wojciechowski Magdalena N., Schreiber Sebastian, Jose Joachim. (). A Novel Flow Cytometry-Based Assay for the Identification of HCN4 CNBD Ligands. Pharmaceuticals, 16. doi: 10.3390/ph16050710.
    • Jung Jaeyong, Bong Ji-Hong, Soo Sung Jeong, Park Jun-Hee, Kim Tae-Hun, Kwon Soonil, Kang Min-Jung, Jose Joachim, Pyun Jae-Chul. (). Immunoaffinity biosensors for the detection of SARS-CoV-1 using screened Fv-antibodies from an autodisplayed Fv-antibody library. Biosensors and Bioelectronics, 237. doi: 10.1016/j.bios.2023.115439.
    • Lopez-Rojas Priscila, Haidar Samer, Jürgens Franziska M., Aichele Dagmar, Amesty Angel, Estevez-Braun Ana, Jose Joachim . (). Synthesis and biological evaluation of anthracene-9,10 dione derivatives as CK2 inhibitors. Results in Chemistry, 6. doi: 10.1016/j.rechem.2023.100997.
    • Hardebeck Sarah, Schreiber Sebastian, Adick Annika, Langer Klaus, Jose Joachim . (). A FRET-Based Assay for the Identification of PCNA Inhibitors. International Journal of Molecular Sciences (IJMS), 24. doi: https://doi.org/10.3390/ijms241411858.
    • Gasse Cécile, Srivastava Puneet, Schepers Guy, Jose Joachim, Hollenstein Marcel, Marlière Philippe, Herdewijn Piet. (). Controlled E. coli Aggregation Mediated by DNA and XNA Hybridization. ChemBioChem, 24. doi: 10.1002/cbic.202300191.
    • Wegner T, Dombovski A, Gesing K, Köhrer A, Elinkmann M, Karst U, Glorius F & Jose J. (). Combining lipid-mimicking-enabled transition metal and enzyme-mediated catalysis at the cell surface of E. coli. Chemical science, 14. doi: 10.1039/D3SC02960C.
    • Possart K, Herrmann FC, Jose J & Schmidt TJ. (). In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase. Molecules (Basel, Switzerland), 28. doi: 10.3390/molecules28227526.
    • Jung J, Sung JS, Bong J-H, Kim T-H, Kwon S, Bae HE, Kang M-J, Jose J, Lee M, Shin H-J & Pyun J-C. (). One-step immunoassay of SARS-CoV-2 using screened Fv-antibodies and switching peptides. Biosensors and Bioelectronics, 245. doi: https://doi.org/10.1016/j.bios.2023.115834.
    • Possart K, Herrmann FC, Jose J & Schmidt TJ. (). In Silico and In Vitro Search for Dual Inhibitors of the Trypanosoma brucei and Leishmania major Pteridine Reductase 1 and Dihydrofolate Reductase. Molecules (Basel, Switzerland), 28, Article 7526. doi: 10.3390/molecules28227526.
    • Sung JS, Jung J, Hwang H, Bong J-H, Kang M-J, Jose J, Lee M & Pyun J-C. (). Screening of Pancreatic Ribonuclease A Inhibitors from an Autodisplayed Fv-Antibody Library. ACS Pharmacology and Translational Science, 6. doi: 10.1021/acsptsci.3c00232.
    • Gesing K, Lenz F, Schreiber S, Kasimir M, Humpf H-U & Jose J. (). Surface Display and Engineering of Laccase CotA for Increased Growth of Pseudomonas putida on Lignin. ChemCatChem, 16. doi: 10.1002/cctc.202301055.

    • Tian H, Furtmann C, Lenz F, Srinivasamurthy V, Bornscheuer U & Jose J. (). Enzyme cascade converting cyclohexanol into εcaprolactone coupled with NADPH recycling using surface displayed alcohol dehydrogenase and cyclohexanone monooxygenase on E. coli. Microbial Biotechnology, 15(8). doi: 10.1111/1751-7915.14062.
    • Asif M, Kaygusuz E, Shinawi M, Nickelsen A, Hsieh T-C, Wagle P, Budde B, Hochscherf J, Höhne W, Höning S, Lindenblatt D, Noegel A, Altmüller J, Thiele H, Motameny S, Segal I, Tinschert S, Samra N, Savatt J, Rudy N, Fortugno P, Krawitz P, Hurst A, Niefind K, Jose J, Brancati F, Nürnberg P & Hussain MS. (). De novo variants of CSNK2B cause a new intellectual disability-craniodigital syndrome by disrupting the canonical Wnt signaling pathway. Human Genetics and Genomics Advances, 3(3). doi: 10.1016/j.xhgg.2022.100111.
    • Park Jong-Min, Kim Mi Yeon, Jose Joachim, Park Min. (). Covalently Immobilized Regenerable Immunoaffinity Layer with Orientation-Controlled Antibodies Based on Z-Domain Autodisplay. International Journal of Molecular Sciences (IJMS), 23.
    • Soo Sung Jeong, Bong Ji-Hong, Lee Soo Jeong, Jung Jaeyong, Kang Min-Jung, Lee Misu, Shim Won-Bo, Jose Joachim, Pyun Jae-Chul. (). One-step immunoassay for food allergens based on screened mimotopes from autodisplayed FV-antibody library. Biosensors and Bioelectronics, 202.
    • Possart K, Herrmann FC, Jose J, Costi MP & Schmidt TJ. (). Sesquiterpene Lactones with Dual Inhibitory Activity against the Trypanosoma brucei Pteridine Reductase 1 and Dihydrofolate Reductase. Molecules, 27, 149. doi: 10.3390/molecules27010149.
    • Bayart Caroline, Mularoni Angélique, Hemmani Nada, Kerachni Soumeya, Jose Joachim, Gouet Patrice, Paladino Joseph, Le Borgne Marc. (). Tetanus Toxin Fragment C: Structure, Drug Discovery Research and Production. Pharmaceuticals, 15(6). doi: 10.3390/ph15060756.
    • Bhatia Sanil, Spanier Lukas, Bickel David, Dienstbier Niklas, Woloschin Vitalij, Vogt Melina, Pols Henrik, Lungerich Beate, Reiners Jens, Aghaallaei Narges, Diedrich Daniela, Frieg Benedikt, Schliehe-Diecks Julian, Bopp Bertan, Lang Franziska, Gopalswamy Mohanraj, Loschwitz Jennifer, Bajohgli Baubak, Skokowa Julia, Borkhardt Arndt, Hauer Julia, Hansen Finn K., Smits Sander H. J., Jose Joachim, Gohlke Holger, Kurz Thomas. (). Development of a First-in-Class Small-Molecule Inhibitor of the C-Terminal Hsp90 Dimerization. ACS Central Science, 8(5). doi: 10.1021/acscentsci.2c00013.
    • Werner Christian, Gast Alexander, Lindenblatt Dirk, Nickelsen Anna, Niefind Karsten, Jose Joachim, Hochscherf Jennifer. (). Structural and Enzymological Evidence for an Altered Substrate Specificity in Okur-Chung Neurodevelopmental Syndrome Mutant CK2αLys198Arg. Frontiers in molecular biosciences, 9. doi: https://doi.org/10.3389/fmolb.2022.831693.
    • Palei Shubhendu, Jose Joachim & Mootz Henning D. (). Preparation of Bacterial Cell-Surface Displayed Semisynthetic Cyclic Peptides. In Coppock, Matthew B; Winton, Alexander J (Eds.), Peptide macrocycles : methods and protocols (pp. 1–469). New York: Humana Press. doi: https://doi.org/10.1007/978-1-0716-1689-5_11.
    • Eenink Bernard D. G., Kaminski Tomasz S., Bornberg-Bauer Erich, Jose Joachim, Hollfelder Florian, van Loo Bert. (). Vector Redesign and In-Droplet Cell-Growth Improves Enrichment and Recovery in live Escherichia coli. Microbial Biotechnology, 15(11). doi: 10.1111/1751-7915.14144.
    • Sung Jeong Soo, Bong Ji-Hong, Yun Tae Gyeong, Han Yeonju, Park Yusun, Jung Jaeyong, Lee Soo Jeong, Kang Min-Jung, Jose Joachim, Lee Misu, Pyun Jae-Chul. (). Antibody-Mediated Screening of Peptide Inhibitors for Monoamine Oxidase-B (MAO-B) from an Autodisplayed FV Library. Bioconjugate Chemistry, 33. doi: 10.1021/acs.bioconjchem.2c00107.

    • Jung Jaeyong, Bong Ji-Hong, Kim Moon-Ju,Lee Soo Jeong, Sung Jeong Sung, Lee Misu, Kang Min-Jung, Song Jungsik, Jose Jose, Pyun Jae-Chul. (). Screening of Fv Antibodies with Specific Binding Activities to Monosodium Urate and Calcium Pyrophosphate Dihydrate Crystals for the Diagnosis of Gout and Pseudogout. ACS Applied Bio Materials, 2021.
    • El-Awaad Ehab, Birus Robin, Marminon Christelle, Bouaziz Zouhair, Ballentin Laurens, Aichele Dagmar, Le Borgne Marc, Jose Joachim. (). Broad-Spectrum Anticancer Activity and Pharmacokinetic Properties of a Prenyloxy-Subsituted Ideno[1,2-b]indole Derivative, Discovered as CK2 Inhibitor. Pharmaceuticals, 14, 542.
    • Nickelsen Anna, Jose Joachim. (). Label-free flow cytometry-based enzyme inhibitor identification. Analytical Chimical Acta, 1179, 338826.
    • Lindenblatt Dirk, Applegate Violetta, Nickelsen Aanna, Klußmann Merlin, Neundorf Ines, Götz Claudia, Jose Joachim, Niefind Karsten. (). Molecular Plasticity of Crystalline CK2α‘ Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. Journal of Medicinal Chemistry, 1.
    • Rajan Remya, Schepmann Dirk, Steigerwald Ruben, Schreiber Julian Alexander, El-Awaad Ehab, Jose Joachim, Seebohm Guiscard, Wünsch Bernhard. (). [2.2]Paracyclophane-based TCN-201 analogs as GluN2A-selective NMDA receptor antagonists. ChemMedChem, 16, –110.
    • Haidar Samer, Jürgens Franziska, Aichele Dagmar, Jagels Annika, Humpf Hans-Ulrich, Jose Joachim. (). Natural compounds isolated from Stachybotrys chartarum are potent inhibitors of human protein kinase CK2. Molecules, 26, 4453.
    • Jung Jaeyong, Bong Ji-Hong, Sung Jeong Soo, Lee Soo Jeong, Lee Misu, Kang Min-Jung, Jose Joachim, Pyun Jae-Chul. (). Fluorescein and Rhodamine B‑Binding Domains from Autodisplayed Fv-Antibody Library. Bioconjugate Chemistry, 32(10). doi: 10.1021/acs.bioconjchem.1c00376.
    • Birus Robin, El-Awaad Ehab, Ballentin Laurens, Alchab Faten, Aichele Dagmar, Ettouati Laurent, Götz Claudia, Le Borgne Marc, Jose Joachim. (). 4,5,7-Trisubstituted indeno[1,2-b]indole inhibits CK2 activity in tumor cells equivalent to CX-4945 and shows strong anti-migratory effects. FEBS Open Bio, 12(2). doi: 10.1002/2211-5463.13346.
    • Haidar Samer, Jürgens Franziska, Aichele Dagmar, Jose Joachim. (). In Silico and In Vitro Studies of Natural Compounds as Human CK2 Inhibitors. Current Computer-Aided Drug Design, 17(2). doi: 10.2174/1573409916666200311150744.
    • Haidar Samer , Jürgens Michaela Franziska , Aichele Dagmar , Jagels Annika , Humpf Hans-Ulrich , Jose Joachim. (). Natural Compounds Isolated from Stachybotrys chartarum Are Potent Inhibitors of Human Protein Kinase CK2. Molecules (Basel, Switzerland), 26(15), 4453. doi: 10.3390/molecules26154453.

    • Haidar S, Marminon C, Aichele D, Nacereddine A, Zeinyeh W, Bouzina A, Berredjem M, Ettouati L, Bouaziz Z, Le Borgne M & Jose J. (). QSAR model of indeno[1,2-b]indole derivatives and identification of N-isopentyl-2-methyl-4,9-dioxo-4,9-dihydronaphtho[2,3-b]furan-3-carboxamide as potent CK2 inhibitor. Molecules, 25(1), 97.
    • Tozakidis IEP, Lüken LM, Üffing A & Meyers A and Jose J. (). Improving the autotransporter-based surface display of enzymes in Pseudomonas putida KT2440. Microb Biotechnol, 13, 176–184.
    • Bouzina A, Berredjem M, Nocentini A, Bua S, Bouaziz Z, Jose J, Le Borge M, Marminon C, Gratteri P & Supuran CT. (). Ninhydrins inhibit carbonic anhydrases directly binding to the metal ion. European Journal of Medicinal Chemistry, 1. [accepted / in Press (not yet published)]
    • Lindenblatt D, Nickelsen A, Applegate V, Jose J & Niefind K. (). Structural and mechanistic basis of the inhibitory potency of selected 2-aminothiazole compounds on protein kinase CK2. J Med Chem, 1. [accepted / in Press (not yet published)]
    • Spiegler V, Gierlikowska B, Saenger T, Addotey J, Sendker J, Jose J, Kiss AK & Hensel A. (). Root Extracts from Ononis spinosa inhibit IL-8 Release via Interactions with Toll-like receptor 4 and Lipopolysaccharide. Front Pharmacol, 11.
    • Lee GY, Bong JH, Jung J, Kang MJ, Jose J & Pyun JC. (). Application of a thermophoretic immunoassay in the diagnosis of lupus using outer membrane particles from E. coli. Biosens Bioelectron, 156, 112110.
    • Lengers I, Herrmann F, Le Borgne M & Jose J. (). Improved surface display of human Hyal1 and identification of testosterone propionate and chicoric acid as new inhibitors. Pharmaceuticals, 13, 54.
    • Lenz F, Zurek P, Umlauf M, Tozakidis IEP & Jose J. (). Tailor-made β-glucosidase with increased activity at lower temperature without loss of stability and glucose tolerance. Green Chemistry, 22, 2234–2243.
    • Kröger L, Daniliuc CG, K, Ensan D, Borgert S, Nienberg C, Lauwers M, Steinkrüger M, Jose J, Peitsch M & Wünsch B. (). Synthesis and SAR of tetracyclic inhibitors of the kinase CK2 derived from furocarbazole W16. ChemMedChem, 15, 871–881.
    • Pietsch M, Viht, K, Schnitzler A, Ekambaram R, Steinkrüger M, Enkvist E, Nienberg C, Nickelsen A, Lauwers M, Jose J, Uri A & Niefind K. (). Unexpected CK2β-antagonistic functionality of bisubstrate inhibitors targeting protein kinase CK2. Bioorg. Chem., 96, 103608.
    • Lengers I, Herrmann F, Le Borgne M & Jose J. (). Improved surface display of human hyal1 and identification of testosterone propionate and chicoric acid as new inhibitors. Pharmaceuticals, 13.
    • Strätker, Katja, Haidar Sama, Dubiel Marian, Estevez-Braun Ana. (). Autodisplay of human PIP5K1α lipid kinase on Escherichia coli and inhibitor testing. Enzyme Microbial Technology, 143.

    • Oramas-Royo S, Haidar S, Amesty A, Martín-Acosta P, Feresin G, Tapia A, Aichele D, Jose J & Estévez-Braun A. (). Design, synthesis and biological evaluation of new embelin derivatives as CK2 inhibitors. Bioorg. Chem., 95.
    • Strätker K, Haidar S, Amesty A, El-Awaad E, Götz C, Estévez-Braun A & Jose J. (). Development of an in vitro screening assay for PIP5K1α lipid kinase and identification of potent inhibitors. The FEBS Journal, 1.
    • Lindenblatt D, Nickelsen A, Applegate V, Hochscherf J, Witulski B, Bouaziz Z, Marminon C, Bretner M, Le Borgne M, Jose J & Niefind K. (). Diacritic binding of an indenoindole inhibitor by CK2α paralogs explored by a reliable path of atomic resolution CK2α' structures. ACS Omega, 4, 4571–4578.
    • Meyers A, Furtmann C, Gesing K, Tozakidis IEP & Jose J. (). Cell density-dependent auto-inducible promoters for expression of recombinant proteins in Pseudomonas putida. Microb Biotechnol, 12(5), 1003–1013.
    • Su W, Matsumoto S, Banine F, Srivastava T, Dean J, Foster S, Hammond B, Peters A, Girish K, Rangappa K, Basappa S, Jose J, Hennebold J, Murphy M, Bennet-Toomey J, Back S & Sherman L. (). A modified flavonoid accelerates oligodendrocyte maturation and functional remyelination. Glia, 68, 263-279.
    • Haidar S, Aichele D, Birus R, Hielscher J, Laitinen T, Poso A & Jose J. (). In vitro and in silico evaluation of bikaverin as a potent inhibitor of human protein kinase CK2. Molecules, 24, 1380.
    • Oloketuyi S, Dilkaute C, Mazzega E, Jose J, de Marco A. (). Purification-independent immunoreagents obtained by displaying nanobodies on bacteria surface. Applied Microbiology and Biotechnology, 103, 4443–4453.
    • Hensel A, Lengers I, Jose J & Addotey J N. (). Hyal-1 inhibitors from the leaves of Phyllanthus muellerianus (Kuntze) Excell. Journal of Ethnopharmacology, 236, 326–335.
    • Dilkaute C, Schepmann D, Schreiber J, Wünsch B & Jose J. (). Autodisplay of the NMDA receptor GluN1 ligand bindig domain and lignad binding studies. In Frontiers in Medicinal Chemistry, Würzburg.
    • Tian H, Quehl P, Hollender J, Reichel J & Jose J. (). Toward drug metabolism studies with autodisplay of human cytochrome P450 enzymes 3A4, 1A2, 2C9, 2C19 and 2D6 and cytochrome P450 reductase. In Frontiers in Medicinal Chemistry, Würzburg.
    • Schulte M, Saenger T, Vordenbäumen S, Genich S, Haidar S, Bleck E, Schneider M & Jose J. (). Human αS1-casein binds to the ecto domain of TLR4/MD2 and induces IL-8 secretion. In Frontiers in Medicinal Chemistry, Würzburg.
    • Hardebeck S, Bopp B, De Biasio A & Jose J. (). A New Assay for Testing the p15PAF-PCNA Interaction and Design of a First Peptidic Inhibitor. In Frontiers in Medicinal Chemistry, Würzburg.
    • Nickelsen A & Jose J. (). Photo-Crosslinking at the Cell Surface for the Identification of Binding Partners of Human Protein Kinase CK2. In ANAKON 2019, Münster.
    • Birus R, Aichele D, Le Borgne M & Jose J. (). Live Cell Imaging and HPLC-MS/MS for Analyzing the Cellular Effects of Human Protein Kinase CK2 Inhibitors with an Indeno[1,2-b]indole Scaffold. In ANAKON 2019, Münster.
    • Birus R, Aichele D, Le Borgne M & Jose J. (). Analyzing the Effects of CK2 Inhibitors with an Indeno[1,2-b]indole Scaffold on Different Tumor Cell Lines by Live Cell Imaging and HPLC-MS/MS. In Mosbacher Kolloquium, Mosbach.
    • Saenger T, Vordenbäumen S, Genich S, Haidar S, Schulte M, Nienberg C, Bleck E, Schneider M & Jose J. (). Human αS1-casein induces IL-8 secretion by binding to the ecto-domain of the TLR4/MD2 receptor complex. Biochimica et Biophysica Acta, 1863, 632–643.
    • van Loo B, Heberlein M, Mair P, Zinchenko A, Schüürmann J, Eenink B, Dilkaute C, Jose J, Hollfelder F & Bonberg-Bauer E. (). High-Throughput, Lysis-free Screening for Sulfatase Activitiy Using Eschericha coli Autodisplay in Microdoplets. ACS Catalysis, 1. [accepted / in Press (not yet published)]
    • Lee G-Y, Bong J-H, Yoo G, Kim J-Y, Park M, Kang M-J, Jose J & Pyun J-C. (). Thermophoretic diagnosis of autoimmune diseases based on Escherichia coli with autodisplayed autoantigens. Analytica Chimica Acta, 1055, 106–114.
    • Palei S, Becher KS, Nienberg C, Jose J & Mootz HD. (). Bacterial Cell Surface Display of Semi-Synthetic Cyxlix Peptides. ChemBio Chem, 20, 72–77.

    • Nickelsen A, Nienberg C & Jose J. (). Combining Bacterial Surface Display and Photocrosslinking for Analyzing Protein-Protein-Interactions of Human Protein Kinase CK2. In Frontiers in Medicinal Chemistry, Jena, Deutschland.
    • Lee G-Y, Park M, Kang M-J, Jose J & Pyun J-C. (). Thermophoretic immunoassay based on autodisplayed Z-domains for the detection of C-reactive protein. Sensors & Actuators: B. Chemical, 2018(258), 1131–1137.
    • Bong J-H, Song H-W, Kim T-H, Kang M-J, Jose J & Pyun J-C. (). Refolding of autodisplayed anti-NEF scFv through oxidation with glutathione for immunosensors. Biosensors and Bioelectronics, 102, 609. doi: 10.1016/j.bios.2017.12.009.
    • Martín-Acosta P, Haidar S, Amesty A, Aichele D, Jose J & Estévez-Braun A. (). A new family of highly functionalized pyranobenzoquinones as potent human protein kinase CK2 inhibitors. Eur J Med Chem, 144, 410–423.
    • Nacereddine A, Bollacke A, Róka E, Marminon C, Bouaziz Z, Fenyvesi F, Bácskay IK, Jose J, Perret F & Le Borgne M. (). Self-assembled supramolecular nanoparticles improve the cytotoxic efficacy of CK2 inhibitor THN7. Pharmaceuticals, 11, 10.
    • Haidar S, Jabbour M, Al-Khayat MA, Aichele D & Jose J. (). Synthesis and biological evaluation of novel 2(4’-hydroxynaphthyl)chromen-4-one as a CK2 inhibitor. Die Pharmazie, 73, 191–195.
    • Bhatia S, Diedrich D, Frieg B, Stein S, Bopp B, Lang F, Zang T, Kröger T, Ernst T, Kögler G, Krieg A, Lüdeke S, Kunkel H, Rodrigues Moita AJ, Kassack MU, Marquardt V, Remke M, Grez M, Hochhaus A, Borkhardt A, Groth G, Nagel-Steger L, Jose J, Kurz T, Gohlke H, Hansen FK & Hauer J. (). Targeting HSP90 dimerization via the C-terminus is effective in imatinib-resistant CML and lacks heat shock response induction. Blood, 132, 307–320.
    • Obeng EM, Brossette T, Ongkudon CM, Budiman C, Maas RM & Jose J. (). The workability of Escherichia coli BL21 (DE3) and Pseudomonas putida KT2440 expression platforms with autodisplayed cellulases: a comparison. Appl Microbiol Biotechnol, 102, 4829–4841. doi: 10.1007/s00253-018-8987-4..
    • Nienberg C, Garmann C, Bollacke A, Saenger T, Gratz A & Jose J. (). Screening for new inhibitors of human protein kinase CK2 by combining click chemistry and bacterial surface display. In Internaional PhD Students/Postdoc Meeting of the German Pharmaceutical Society (DPhG) Pfalz, Pfalz, Deutschland.
    • Gesing K, Lenz F, Tozakidis IEP & Jose J. (). Semi-rational protein engineering to improve the activity of surface displayed exocellulase CelK. In 69. Mosbacher Kolloquium - "Synthetic Biology - from Understanding to Application”, Mosbach, Deutschland.
    • Eenink B, Heberlein M, Mair P, Schüürmann J, Dilkaute C, Jose J, Hollfelder F, Bornberg-Bauer E, van Loo B. (). Ancestral reconstruction and experimental testing of long- and short term evolvability using the AP-superfamily as a model system. In 7th Annual Symposium of the Münster Graduate School of Evolution, Münster, Deutschland.
    • Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H & Hensel A. (). Niedermolekulare Bestandteile reduzieren kurzkettige Hyaluronsäure-Moleküle. Pharmazeutische Zeitung, 2018(163), 43–47.
    • Lenz F, Siemer S, Tozakidis IEP, Maas R & Jose J. (). Metabolic engineering for heterologous ethanol production by Pseudomonas putida. In 69. Mosbacher Kolloqium, Mosbach, Deutschland.
    • Nienberg C, Garmann C, Bollacke A, Saenger T, Gratz A & Jose J. (). Allosteric Inhibitors of Human Protein Kinase CK2: Identification by Click Chemistry and Bacterial Surface Display. In Frontiers in Medicinal Chemistry, Jena, Deutschland.
    • Bloch S, Neman-Falenczyk B, Pierzynowska K, Piotrowska E, Wegrzyn A, Marminon C, Bouaziz Z, Nebois P, Jose J, Le Borgne M, Saso L & Wegrzyn G. (). Inhibition of Shiga toxin-converting bacteriophage development by novel antioxidant compounds. J Enz Inhib Med Chem, 33, 639–650. doi: 10.1080/14756366.2018.1444610.
    • Schnitzler A, Andreas Gratz A, Bollacke A, Weyrich M, Kuckländer U, Wünsch B, Götz C, Niefind K & Jose J. (). A π-halogen bond of dibenzofuranones with the gatekeeper Phe113 in human protein kinase CK2 leads to potent tight binding inhibitors. Pharmaceuticals, 11, 23.
    • Motealleh A, Hermes H, Jose J & Kehr NS. (). Chirality-dependent cell adhesion and enrichment in janus nanocomposite hydrogels. Nanomedicine: NBM, 14, 247–256.
    • Dilkaute C, De Marco A & Jose J. (). Autodisplay of Nanobodies. In DPHG-Jahrestagung 2018, Hamburg.
    • Lengers I, Brandt S, Hensel A & Jose J. (). Hyaluronidase-1 inhibitors provided by nature - marshmallow root extract effecting Hyal1 on protein and gene level. In DPHG-Jahrestagung 2018, Hamburg.
    • Nickelsen A, Nienberg C & Jose J. (). Studying Protein Protein Interactions in Human Protein Kinase CK2 by Click Chemistry and Photocrosslinking. In DPHG-Jahrestagung 2018, Hamburg.
    • Tian H, Quehl P, Hollender J, Schuhmacher S, Reichel J, Jose J . (). Autodisplay of human cytochrome P450 enzymes 3A4, 1A2, 2C9, 2C19 and 2D6 and cytochrome P450 reductase for drug metabolite studies. In DPHG-Jahrestagung 2018, Hamburg.
    • Lenz F, Tozakidis I, Maas R & Jose J. (). Saccharification of lignocellulosic biomass by Pseudomonas putida with surface displayed cellulases. In Pseudomonas Grassroots Meeting, Frankfurt.
    • Meyers A, Furtmann C, Lüken L & Jose J. (). Autotransporter-based surface display of recominant proteins on Pseudomonas putida KT2440. In Pseudomonas Grassroots Meeting, Frankfurt.
    • Jeon D, Pyun J-C, Jose J & Park M. (). Regenerative immunoaffinity layer based on the outer membrane of Z-dominans autodisplaying E.coli for SPR immunosensor. Biosensors, Immunosensors - 2018 Trends and Perspective, 18, 4030.
    • Addotey JN, Lengers I, Jose J, Gampe N, Béni S, Petereit F & Hensel A. (). Isoflavonids with inhibiting effects on human Hyaluronidase-1 and norneolignan Clitorienolactone B from Ononis spinosa L. root extract. Fitoterapia, 130, 169–174.
    • Esch S, König S, Bopp B, Jose J, Brandt S, Hensel. (). Cryptotanshinone from Salvia miltiorrhiza roots reduces cytokeratin CK1/10 expression in keratinocytes by activation of peptidyl-prolyl-cis-trans-isomerase FKBP1A. Planta Medica, 85, 552–562.
    • Meyers, A., Furtmann, C. & Jose, J. (). Direct optical density determination of bacterial cultures in microplates for high-throughput screening applications. Enzyme and Microbial Technology, 18, 1–5. doi: 10.1016.
    • Obeng E, Ongkudon C, Budiman C, Maas R & Jose J. (). An optimal blend of single autodisplayed cellulases for cellulose saccharification – a proof of concept. J Chem Technol Biotechnol, 7, 2729–2736. doi: 10.1002/jctb.5628.

    • Saenger T, Vordenbäumen S, Genich S, Nienberg C, Schulte M, Bleck E, Schneider M & Jose J. (). Microscale thermophoresis for measuring the interaction of the proinflammatory αS1-casein and its cellular receptor TLR4. In Forschung der Chemischen Inudstrie (Symposium), Münster, Deutschland.
    • Nienberg C, Garmann C, Gratz A, Bollacke A, Götz C & Jose J. (). Identification of a Potent Allosteric Inhibitor of Human Protein Kinase CK2 by Bacterial Surface Display Library Screening. In Forschung der Chemischen Industrie (Symposium), Münster.
    • Lengers I, Hermann F, Haidar S & Jose J. (). Human Hyal‑1 – from in silico pharmacophore modeling to in vitro inhibitor screening. In Summerschool WWU.USP.ND 2017, Ribeirao Preto, SP, Brazil.
    • Meyers A, Furtmann C & Jose J. (). A high-throughput-compatible method to determine the optical density of bacterial cell cultures in microplates without sample dilution. In Summerschool WWU.USP.ND 2017, Ribeirao Preto, SP, Brazil.
    • Saenger T, Vordenbäumen S, Genich S, Nienberg C, Schulte M, Bleck E, Schneider M & Jose J. (). Identification of the Binding Site of Proinflammatory αS1-Casein to its Cellular Receptor-complex TLR4 Using Microscale Thermophoresis. In GDCh-Wissenschaftsforum Chemie 2017, Berlin.
    • Nickelsen A, Nienberg C & Jose J. (). Click chemistry based fluorescent labelling of surface displayed proteins on Escherichia coli. In DPhG-Jahrestagung, Saarbrücken, Deutschland.
    • Kröger L, Steinkrüger M, Nienberg C, Borgert SR, Pietsch M, Niefind K, Jose J & Wünsch B. (). Development of protein-protein interaction inhibitors to affect the heterotetrameric architecture of protein kinase CK2. In DPhG Jahrestagung, Saarbrücken, Deutschland.
    • Lengers I, Hermann F, Orlando Z, Melzig MF, Buschauer A, Haidar S, Hensel A & Jose J. (). Sekundäre Pflanzeninhaltsstoffe als Hemmstoffe der humanen Hyal 1 – eine Kombination aus in silico und in vitro Experimenten. In Phytotherapiekongress 2017, Münster, Deutschland.
    • Addotey J, Lechtenberg M, Petereit F, Lengers I, Jose J & Hensel A. (). Naturstoffe als Inhibitoren der humanen Hyaluronidase-1. In Phytotherapiekongress 2017, Münster, Deutschland.
    • Dilkaute C, Weckenbrock W & Jose J. (). Developing a full-length IgG antibody library displayed on the surface of Escherichia coli. In DPhG Jahrestagung, Saarbrücken, Deutschland.
    • Dilkaute C, Weckenbrock W & Jose J. (). Display of a full length IgG antibody on the surface of Escherichia coli: Towards the screening of an antibody library. In 3rd International Electronic Conference on Medicinal Chemistry, International.
    • Tozakidis IEP, Schulte MF, Pupkes H, Lenz F, Maas R & Jose J. (). Lignocellulose degradation with surface displayed enzymes on Pseudomonas putida. In The European Summit of Industrial Biotechnology, Graz, Österreich.
    • Haidar S, Bouaziz Z, Marminon C, Laitinen T, Poso A, Le Borgne M, Jose J . (). Development of pharmacophore model for indeno[1,2-b]indoles as human protein kinase CK2 inhibitors and database mining. In DPhG Jahrestagung, Saarbrücken, Deutschland.
    • Saenger T, Vordenbäumen S, Genich S, Haidar S, Bleck E, Schneider M & Jose J. (). Analysis of the binding site of αS1-casein to its cellular receptor TLR4 by selective inhibitors and microscale thermophoresis. In 3rd International Electronic Conference on Medicinal Chemistry, 1.-30.11.2017., Sciforum Electronic Conference Series.
    • Herrmann FC, Sivakumar N, Jose J, Costi MP, Pozzi C & Schmidt TJ. (). In silico identification and in vitro evaluation of natural inhibitors of Leishmania major Pteridine reductase I. Molecules: Special Issue "COST CM1307: Targeted Chemotherapy towards Diseases Caused by Endoparasites -Proceedings in Medicinal and Natural Product Chemistry, 22(12), 2166. doi: 10.3390/molecules22122166.
    • Hochscherf J, Lindenblatt D, Witulski B, Birus R, Aichele D, Marminon C, Bouaziz Z, Le Borgne M, Jose J & Niefind K. (). Unexpected binding mode of a potent indeno[1,2-b]indole-type inhibitor of protein kinase CK2 revealed by complex structures with the catalytic subunit CK2α and its paralog CK2α’. Pharmaceuticals, 10(4), 98.
    • Nienberg C, Garmann C, Saenger T, Bollacke A, Gratz A & Jose J. (). Click chemistry and bacterial surface display: Identification of new potent allosteric inhibitors of human protein kinase CK2. In GDCh-Wissenschaftsforum Chemie 2017, Berlin.
    • Lengers I, Hermann F, Haidar S, Jose J . (). Human Hyal‑1 – from in silico pharmacophore modeling to in vitro inhibitor screening. In GP2A 25th Annual Medicinal Chemistry Conference, Liverpool, UK.
    • Koenig S, Altendorfer I, Saenger T, Bleck E, Vordenbäumen S, Schneider M & Jose J. (). Ser71 of αS1-casein is phosphorylated in breast milk – Evidence from targeted mass analysis. Mol Nutr Food Res, 2017. doi: 10.1002/mnfr.201700496.
    • Park M, Pyun J-C & Jose J. (). Orientation and density control of proteins on solid matters by outer membrane coating: Analytical and diagnostic applications. J Pharm Biomed Anal, 147, 174–184.
    • Quehl P, Schüürmann J, Hollender J & Jose J. (). Improving the activity of surface displayed cytochrome P450 enzymes by optimizing the outer membrane linker. BBA - Biomembranes, 1859, 104–116.
    • Meyers A, Furtmann C & Jose J. (). A high-throughput-compatible method to determine the optical density of bacterial cell cultures in microplates without sample dilution. In 4th Summerschool Biotransformations, Hannover, Deutschland.
    • Lenz F, Tozakidis IEP, Brossette T, Maas RM & Jose J. (). Using Pseudomonas putida with surface displayed cellulases as whole cell biocatalyst for degradation of lignocellulosic biomass. In 4th Summerschool Biotransformations, Hannover, Deutschland.
    • Kehr S & Jose J. (). Chirality-dependent cellular uptake of chiral nanocaarriers and intracellular delivery of different amounts of guest molecules. Appl Surf Sci, 425, 432–439.
    • Jose J, Le Borgne M, Pinna LA, Montenarh M (Eds.). (). An updated view on an emerging target: Selected papers from the 8th International Conference on Protein Kinases CK2. Basel: MDPI AG.
    • Schulte MF, Tozakidis IE & Jose J. (). Autotransporter-based surface display of hemicellulase on Pseudomonas putida: new whole-cell biocatalysts for the production of xylose from biomass. ChemCatChem, 9, 3955–3964. doi: 10.1002/cctc.201700577.
    • Schüürmann J, Quehl P, Lindhorst F, Lang K & Jose J. (). Autodisplay of glucose-6-phosphate dehydrogenase for redox cofactor regeneration at the cell surface. Biotech Bioeng, 114, 1658–1669. doi: 10.1002/bit.26308.
    • Oerding K, Kaiser L, Kranen E, Maas RM & Jose J. (). Autodisplay-supported biocatalysis in deep eutectic solvents. In Biocatalysis for non-conventional media, Rostock, Deutschland.
    • Obeng EM, Adam SNN, Budiman C, Ongkudon CM, Maas R & Jose J. (). Lignocellulases: a review of emerging and developing enzymes, systems, and practices. Bioresour Bioprocess, 4:16. doi: 10.1186/s40643-017-0146-8.
    • Pyun J-C, Jose J & Park M. (). Development of a wash-free immunoassay using Escherichia coli cells with autodisplayed Z-domains. Analyst, 142, 1720–1728.
    • Jose J, Le-Borgne M, Pinna LA & Montenarh M. (). An Updated View on an Emerging Target: Selected Papers from the 8th International Conference on Protein Kinase CK2. Pharmaceuticals, 10(33).
    • Gisbert Fenoy C, Raudszus B, Langer K & Jose J. (). Surface display of LRP1-IV and ApoE3 on E. coli for the development of new drug delivery systems across the blood-brain barrier. In 24th Edition of the Young Researcher Fellow's Meeting of the French Medicinal Chemistry Society, Paris.
    • Sendker J, Böker I, Lengers I, Brandt S, Jose J, Stark T, Hofmann T, Fink C, Abdel-Aziz H & Hensel A. (). Phytochemical characterization of low molecular constitutents from marshmallow roots (Althaea officinalis) and inhibiting effects of the aqueous extract on human hyaluronidase-1. J Nat Prod, 80, 290–297. doi: 10.1021/acs.jnatprod.6b00670.
    • Yoo G, Bong J-H, Song H-W, Dilkaute C, Kang M-J, Jose J & Pyun J-C. (). Autodisplay of the La/SSB protein on LPS-free E. coli for the diagnosis of Sjögren’s syndrome. Enzyme Microb Tech, 100, 1–10.
    • Haidar S, Bouaziz Z, Marminon C, Laitinen T, Poso A, Le Borgne M & Jose J. (). Development of pharmacophore model for indeno[1,2-b]indoles as human protein kinase CK2 inhibitors and database mining. Pharmaceuticals, 10(8).
    • Nienberg C, Reicheneder C, Gratz A, Bollacke A, Götz C & Jose J. (). Identification of a potent allosteric inhibitor of human protein kinase CK2 by bacterial surface display library screening. Pharmaceuticals, 10.
    • Chang S-Y, Bong J-H, Yoo G, Jose J, Kang M-J & Pyun J-C. (). Activity control of autodisplayed lipase and foldase on the outer membrane of Escherichia coli. . Enzyme Microb Tech, 96, 85–95.
    • Kehr N. & Jose J. (). Chirality-dependent cellular uptake of chiral nanocarriers and intracellular delivery of different amounts of guest molecules. Applied Surface Science, 425, 432–439. doi: 10.1016/j.apsusc.2017.07.052.
    • Herrmann FC, Sivakumar N, Jose J, Costi MP & Schmidt TJ. (). In Silico Identification and In Vitro Evaluation of Natural Inhibitors of Leishmania major Pteridine Reductase I. Molecules, 22, 2166. doi: 10.3390/molecules22122166.
    • Lengers I, Herrmann F, Haidar S & Jose J. (). Human Hyal-1 - frm in silico pharmacophore modeling to in vitro inhibitor screening. In 3rd International Electronic Conference on Medicinal Chemistry, Online-Symposium.

    • Schüürmann J, Lindhorst F & Jose J. (). NADPH cofactor regeneration with surface displayed dehydrogenases. In Forschung der Chemischen Industrie (Symposium), Münster, Deutschland.
    • Nienberg C, Retterath A, Becher K-S, Saenger T, Mootz HD & Jose J. (). Development of screening assays for human protein kinase CK2 using the advantages of click chemistry. . In Forschung der Chemischen Industrie (Symposium), Müsnter, Deutschland.
    • Gisbert Fenoy C & Jose J. (). Glowing Chemistry: Fluorescent Labeling of E. coli and Surface Exposed Proteins. In 7th Münster Symposium on Cooperative Effects in Chemistry, Münster, Deutschland.
    • Quehl P, Hollender J, Schüürmann J, Brossette T, Maas R & Jose J. (). Co-expression of active human cytochrome P450 1A2 and cytochrome P450 reductase on the cell surface of Escherichia coli. Microbial Cell Factories, 15, 26.
    • Le Borgne M, Haidar S, Duval O, Wünsch B, Jose J . (). Proceedings of the 1st Joint European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC 2015). Pharmaceuticals, 9(1), 1.
    • Bopp B, Ciglia E, Ouald-Chaib A, Groth G, Gohlke H & Jose J. (). Design and biological testing of peptidic dimerization inhibitors of human Hsp 90 that target the C-terminal domain. . BBA General Subjects, 1860, 1043–1055.
    • Bollacke A, Nienberg C, Le Borgne M, Jose J . (). Toward selective CK2alpha and CK2alpha’ inhibitors: Development of a novel whole-cell kinase assay by Autodisplay of catalytic CK2alpha’. J Pharm Biomed Anal, 121, 253–260.
    • Kim DH, Bong JH, Yoo G, Chang SY, Park M, Chang YW, Kang MJ, Jose J, Pyun JC . (). Microbead-based immunoassay using the outer membrane layer of Escherichia coli combined with autodisplay Z-domains. . Appl Surf Sci, 362, 146–153.
    • Sendker J, Böker I, Lengers I, Brandt S, Jose J, Fink C, Abdel-Aziz H & Hensel A. (). New flavon glucuronides and Scopoletin glycosides from the roots of Althaea officinalis L and anti-hyaluronidase-1 activity. In 9th Joint Natural Products Conference, Copenhagen, Denmark. doi: 10.1055/s-0036-1596320.
    • Saenger T, Vordenbäumen S, Tahan T, Nienberg C, Bleck E, Schneider M & Jose J. (). LR4-mediated activation of monocytes by human αS1-casein. In 2nd Electronic Conference on Medicinal Chemistry, Basel.
    • Haidar S, Meyers A & Jose J. (). Design and development of 9,10-dihydrophenanthrene derivatives as inhibitors of human protein kinase CK2. In 2nd Electronic Conference on Medicinal Chemistry, Basel.
    • Aichele D, Le Borgne M, Jose J . (). Indeno[1,2-b]indole inhibitors of human protein kinase CK2 and their impact on different tumor cell lines. 2nd Electronic Conference on Medicinal Chemistry, 1.-30.11.2016. In 2nd Electronic Conference on Medicinal Chemistry, Basel.
    • Guragossian N, Gozzi GJ, Fouillet B, Gustin M-P, Terreux R, Bouaziz Z, Marminon C, Jose J, Di Pietro A, Pasanen M, Le Borgne M . (). Candidate molecule selection based on in silico predicted ADMET properties of 12 indenoindole derivatives. Chem Informatics, 2016(2:6).
    • Schulte M, Sichwart S, Tozakidis IE & Jose J. (). Surface display of hemicellulases on Pseudomonas putida: new whole-cell biocatalysts for the degradation of biomass. In Conference on Advances in Industrial Biotechnology: New Techniques, Substrates and Products for Bioprocesses, Bielefeld.
    • Diedrich D, Bhatia S, Frieg B, Stein S, Bopp B, Lang F, Ernst T, Rodrigues Moita AJ, Rüther A, Lüdeke S, Kassack MU, Hochhaus A, Borkhardt A, Jose J, Kurz T, Gohlke H, Hauer J & Hansen FK. (). α-Aminoxy peptides: from membranolytic anticancer foldamers to the first in class peptidomimetic Hsp90 C-terminal domain dimerization inhibitors. In DPhG Jahrestagung, München, Deutschland.
    • Bopp B, Ciglia E, Hansen FK, Neundorf I, Hochscherf J, Kurz T, Niefind K, Gohlke H & Jose J. (). A novel screening method to identify inhibitors of PPIs based on the Autodisplay technology. In DPhG Jahrestagung, München, Deutschland.
    • Schüürmann J, Lindhorst F & Jose J. (). NADPH cofactor regeneration on the cell surface: an important step to pharmaceutical applications of surface displayed P450 enzymes. In DPhG Jahrestagung, München, Deutschland.
    • Oerding K, Kranen E, Maas RM & Jose J. (). Biocatalysis by Autodisplay system in deep eutectic solvents. In Green Solvents, Kiel, Deutschland.
    • Lengers I, Orlando Z, Brandt S, Melzig M.F, Buschauer A, Hensel A & Jose J. (). Natural compounds for inhibition of human Hyal-1. In 8th Summer School Medicinal Chemistry, Regensburg, Deutschland.
    • Gisbert Fenoy C, Raudszus B, Nienberg C, Langer K & Jose J. (). Surface display of LRP1-IV on E. coli and ApoE3 binding: the key to open the blood-brain barrier. In Workshop and Summer School, Neglected Diseases, Münster, Deutschland.
    • Dilkaute C, Weckenbrock W & Jose J. (). Construction of antibody libraries on the surface of E. coli. In Workshop and Summer School, Neglected Diseases, Münster, Deutschland.
    • Dilkaute C, Weckenbrock W & Jose J. (). Displaying full length IgG antibodies on the surface of E. coli. In 8th Summer School "Medicinal Chemistry", Regensburg, Deutschland.
    • Haidar S, Le Borgne M, Jose J . (). Development of pharmacophore model for a series of indenoindoles as protein kinase CK2 inhibitors. In 8th International Conference on Protein kinase CK2, Homburg, Deutschland.
    • Aichele D, Pataillot J, Le Borgne M & Jose J. (). Effects of Indeno[1,2-b]indol inhibitors of human protein kinase CK2 on different tumor cell lines., Homburg, 6.-9.9.2016. In 8th International Conference on Protein Kinase CK2, Homburg, Deutschland.
    • Nienberg C, Retterath A, Becher K-S, Saenger T, Mootz HD, Jose J . (). Bioorthogonal click reaction of human CK2 subunits in combination with surface display for drug discovery appliations. In 8th International Conference on Protein Kinase CK2, Homburg, Deutschland.
    • Lengers I, Orlando Z, Brandt S, Melzig MF, Buschauer A, Hensel A, Jose J . (). Targeting human hyaluronidase hyal-1 with natural compounds. In 24th GP2A Conference, Angers, Frankreich.
    • Dilkaute C, Weckenbrock W & Jose J. (). Display of full length IgG antibodies on the surface of E. coli for the construction of antibody libraries. . In 24th GP2A, Angers, Frankreich.
    • Quehl P, Hollender J & Jose J. (). Bacterial surface display of human cytochrome P450 1A2 and cytochrome P450 reductase for drug metabolite synthesis. In 17th European Congress on Biotechnology, Krakau, Polen.
    • Schüürmann J. (). Cofactor regeneration via autodisplay – towards industrial application with surface displayed enzyme. In 17th European Congress on Biotechnology, Krakau, Polen.
    • Tozakidis IEP, Brossette T, Lenz F, Maas R & Jose J. (). Combining Pseudomonas putida strains with surface displayed thermophilic endocellulase, exocellulase and β-glucosidase for the cost-efficient breakdown of cellulose. In 17th European Congress on Biotechnology, Krakau, Polen.
    • Lenz F, Tozakidis IEP & Jose J. (). Surface display of cellulases in ethanol producing bacterium Zymobacter palmae. In 17th European Congress on Biotechnology, Krakau, Polen.
    • Nienberg C, Retterath A, Becher K-S, Saenger T, Mootz HD & Jose J. (). Site-specific labeling of protein kinase CK2: Combining surface display and click chemistry for drug discovery applications. Pharmaceuticals, 9(36).
    • Tozakidis IEP, Brossette T, Lenz F, Maas R & Jose J. (). Proof of concept for the simplified breakdown of cellulose by combining Pseudomonas putida strains with surface displayed thermophilic endocellulase, exocellulase and ß-glucosidase. Microb Cell Fact, 15:203. doi: 10.1186/s12934-016-0505-8.
    • Sendker J, Böcker I, Lengers I, Brandt S, Jose J, Abdel-Aziz H & Hensel A. (). Neuartige sulfatierte Flavonglucuronide und Scopoletinglycosid aus den Wurzeln von Althaea officinalis und anti-Hyaluronidase-1-Aktivität wässrigen Eibischextraktes. In Phytotherapie 2016 "Extraktentwicklung - Klinik - Versorgungsforschung", Dreiländertagung mit Symposium Tiermedizin, Bonn.
    • Alchab F, Sibillie E, Ettouati L, Bana E, Bouaziz Z, Mularoni A, Monnio E, Bagrel D, Jose J, Le Borgne M, Chaimbault P . (). Screening of indeno[1,2-b]indoloquinones by MALDI-MS: a new set of potential CDC25 phosphatase inhibitors brought to light. J Enz Inhib Med Chem, 2016. doi: 10.1080/14756366.2016.1201480.
    • Kim D-H, Bong J-H, Yoo G, Chang S-Y, Chang YW, Kang M-J, Jose J, Pyun J-C . (). A magnetite suspension-based washing method for immuoassays using Escherichia coli with autodisplayed Z-domains. Enzyme Microb Tech, 92(1-8).
    • Uttakar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Frampton J & Klempnauer KH. (). Targeting acute myeloid leukemia with a small molecule inhibitor of the Myp/p300 interaction. Blood, 127, 1173–1182.
    • Vordenbäumen S, Saenger T, Braukmann A, Tahan T, Bleck E, Jose J & Schneider M. (). Human casein alpha s1 induces proinflammatory cytokine expression in monocytic cells by TLR4-signaling. Mol Nutr Food Res, 60, 1079–1089.
    • Haidar S, Aichele D, Popp R, Meyers A & Jose J. (). Design and development of 9,10-dihydrophenanthrene derivatives as inhibitors of human protein kinase CK2. In Frontiers in Medicinal Chemistry, Bonn, Deutschland.
    • Bopp B, Ciglia E, Ouald-Schaib A, Groth G, Gohlke H & Jose J. (). Design and biological testing of peptidic dimerization inhibitors of human Hsp90 that target the C-terminal domain. In Frontiers in Medicinal Chemistry, Bonn, Deutschland.
    • Nienberg C, Retterath A & Jose J. (). Click Chemistry for Site Directed Labeling of Surface Displayed Proteins on Escherichia coli. In 7th Münster Symposium on Cooperative Effects in Chemistry, Münster, Deutschland.
    • NADPH Cofactor Regeneration on the Cell Surface: A Requirement for Pharmaceutical Applications of Surface Displayed P450 Enzymes. (). Schüürmann J, Lindhorst F, Jose J. In 7th Münster Symposium on Cooperative Effects in Chemistry, Müsnter, Deutschland.
    • Lengers I, Orlando Z, Melzig MF, Buschauer A, Hensel A & Jose J. (). Natural compounds as human Hyaluronidase Hyal-1 inhibitors . In Frontiers in Medicinal Chemistry, Bonn, Deutschland.
    • Becher K-S, Nienberg C, Jose J, Mootz HD . (). Evolving split inteins using bacterial autodisplay. In 67. Mosbacher Kolloqium, Mosbach, Deutschland.
    • Saenger T, Vordenbäumen S, Tahan T, Nienberg C, Bleck E, Schneider M & Jose J. (). Human alphaS1-casein exerts proinflammatory effects via TLR4-signaling pathway. In Frontiers in Medicinal Chemistry, Bonn, Deutschland. doi: 10.1002/mnfr.201500792.
    • Quehl P, Hollender J & Jose J. (). Towards drug metabolite synthesis with surface displayed human cytochrome P450 1A2 and cytochrome P450 reductase. . In Frontiers in Medicinal Chemistry, Bonn, Deutschland.

    • Quehl P, Riemer J & Jose J. (). Co-expression of Functional Human Cytochrome P450 1A2 and its Reductase on the Surface of Escherichia coli. In Forschung der Chemischen Industrie (Symposium), Münster.
    • Quehl P, Riemer J, Jose J . (). Co-expression of catalytic active human cytochrome P450 reductase and cytochrome P450 1A2 on the surface of Escherichia Coli. In DPhG-Doktorandentagung, Biberach, Deutschland.
    • Tozakidis IE, Quehl P, Schüürmann J, Jose J . (). Let's do it outside: neue Biokatalysatoren mittels surface display. BIOspektrum, 21, 668–671. doi: 10.1007/s12268-015-0628-1.
    • Haidar S, Meyers A, Bollacke A, Jose J . (). Synthesis and biological evaluation of 2,6-Di(furan-3-yl)anthracen-9,10-dione as an inhibitor of human protein kinase CK2 . Die Pharmazie, 70, 772–776.
    • Lengers I, Orlando Z, Melzig MF, Buschauer A, Hensel A, Jose J . (). Inhibition of the cancer target human hyaluronidase Hyal-1 by natural substances. . In 1st International Electronic Conference on Medicinal Chemistry, Electronic.
    • Gisbert Fenoy C., Raudszus B., Zlatev I., Nienberg C., Langer K. & Jose J. (). Screening of nanoparticles for drug-delivery across the blood-brain barrier using autodisplayed LRP1 IV-domain on E. coli. In DPhG Annual Meeting, Düsseldorf, Germany.
    • Uttarkar S, Dukare S, Bopp B, Goblirsch M, Jose J, Klempnauer KH . (). Naphtol AS-E phosphate inhibits the activity of the transcription factor Myb by blocking the interaction with the KIX domain of the coactivator p300. Mol Cancer Ther, 14, 1276–1285.
    • Uttarkar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Trampton J & Klempnauer KH. (). Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction. Blood, 2015. [accepted / in Press (not yet published)]
    • Alchab F, Ettouati L, Bouaziz Z, Bollacke A, Delcros JG, Gertzen CGW, Gohlke H, Pinaud N, Marchivie M, Guillon J, Fenet B, Jose J, Le Borgne M . (). Synthesis, biological evaluation and molecular modeling of substituted indeno[1,2-b]indoles as inhibitors of human protein kinase CK2. Pharmaceuticals, 8(2), 279–302.
    • Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Guragossian N, Marminon C, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena SM, Jose J, LeBorgne M & DiPietro A. (). Phenolic indeno[1,2-b]indoles as ABCG2-selective potent and nontoxic inhibitors stimulating basal ATPase activity. Drug Des Devel Ther, 9, 3481–3495.
    • Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Aichele D, Nacereddine A, Marminon C, Valdameri G, Zeinyeh W, Bollacke A, Guillon J, Lacoudre A, Pinaud N, Cadena S, Jose J, Le Borgne M & Di Pietro A. (). Converting potent indeno[1,2-b]indole inhibitors of protein kinase CK2 into selective inhibitors of the breast cancer resistance protein ABCG2. J Med Chem, 58, 265–277.
    • Haidar S, Meyers A & Bollacke A, J. (). Synthesis and biological determination of a new anthracen-9,10-dione derivative as a human CK2 inhibitor. In 1st International Electronic Conference on Medicinal Chemistry, Internet.
    • Nienberg C, Retterath A, Becher KS, Mootz HD, Jose J . (). Click chemistry for advanced drug discovery applications of human protein kinase CK2. In 1st International Electronic Conference on Medicinal Chemistry, International.
    • Bopp B, Ciglia E, Ouald-Chaib A, Groth G, Gohlke H, Jose J . (). A novel autodisplay based screening assay for the identification of small molecules that inhibit the dimerization of human chaperone Hsp90. In DPhG-Jahrestagung, Düsseldorf.
    • Nienberg C, Becher KS, Mootz HD, Jose J . (). Site specific labelling of human protein kinase CK2 for drug discovery applications. In DPhG-Jahrestagung, Düsseldorf.
    • Lengers I, Orlando Z, Melzig MF, Buschauer A, Hensel A & Jose J. (). Natural substances as inhibitors of the tumor target human hyaluronidase Hyal-1. In DPhG-Jahrestagung, Düsseldorf.
    • Gisbert Fenoy C, Raudszus B, Nienberg C, Langer K, Jose J . (). Screening of nanoparticles for drug delivery across the blood brain barrier using autodisplayed LRP1 IV-domain on E.coli. In DPhG-Jahrestagung, Düsseldorf.
    • Bollacke A, Le Borgne M & Jose J. (). Towards Selective CK2α and CK2α’ Inhibitors: a Novel Screening Assay by Autodisplay of Heterotetrameric Human Protein Kinase CK2. In DPhG-Jahrestagung, Düsseldorf.
    • Yoo G, Saenger T, Bong JH, Jose J, Kang MJ & Pyun JC. (). Co-autodisplay of Z-domains and bovine caseins on the outer membrane of E. coli. Biochim Biophys Acta, 1848, 3126–3133.
    • Quehl P, Hollender J, Jose J . (). Active Human Cytochrome P450 1A2 and Cytochrome P450 Reductase on the Cell Surface of Escherichia coli. . In Biotrans, A-Wien.
    • Jakobs A, Uttarkar S, Jose J, Müller-Tidow C, Schmidt TJ & Klempnauer K-H. (). Inhibition of C/EBPB by the sesquiterpene lactone helenalinacetate. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Guragossian N, Gozzi G J, Bouaziz Z, Winter E, Valdameri G, Terreux R, Marminon C, Boumendje lA, Jose J, Di Pietro A, Le Borgne M . (). Strategies to select the right indeno[1,2-b]indole derivative(s) for ABCG2-targeting in vivo assays. . In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Nienberg C, Becher K, Mootz HD, Jose J . (). Click chemistry for site specific fluorescence labeling of human protein kinase CK2. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Gisbert Fenoy C, Raudszus B, Zlatev I, Nienberg C, Langer K, Jose J . (). Autodisplayed LPR1 IV-domain as a tool for identification of drug delivery agents across the blood-brain barrier. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015,, D-Münster.
    • Bopp B, Ciglia E, Ouald-Chaib A, Groth G, Gohlke H & Jose J. (). An Autodisplay based screening assay for the identification of inhibitors targeting the dimerization domain of human chaperone HSP90. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015,, D-Münster.
    • Weckenbrock W, Blaßhofer F, Klotz LO, Jose J . (). Tumor cell targeting with Escherichia coli displaying anti-EGFR antibody fragments. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Schmithals C, Kröger L, Bollacke A, Jose J & Wünsch B. (). Inhibition of CK2: One target, two strategies. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Nacereddine A, Bouaziz Z, Marminon C, Le Borgne M & Jose J. (). Improved inhibitors of human kinase protein CK2: Synthesis and biological evaluation of substituted indeno[1,2-b]indole derivatives. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Lengers I, Orlando Z, Melzig MF, Buschauer A, Hensel A & Jose J. (). Identification of new plant-derived inhibitors of human hyaluronidase Hyal-1, a target in prostate and bladder cancer. . In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Haidar S, Meyers A, Bollacke A & Jose J. (). Development of new anthracen-9,10-dione derivatives as an inhibitor of human protein kinase CK2. In 1st European Conference on Therapeutic Targets and Medicinal Chemistry (TTMC) 2015, D-Münster.
    • Herrmann FC, Lenz M, Jose J, Kaiser M, Brun R, Schmidt T . (). In silico identification and in vitro activity of novel natural inhibitors of trypanosoma brucei glyceraldehyde-3-phosphate-dehydrogenase. Molecules, 20, 16154–16169.
    • Orlando Z, Lengers I, Melzig MF, Buschauer A, Hensel A, Jose J . (). Autodisplay of human hyaluronidase Hyal-1 on Escherichia coli and identification of plant-derived enzyme inhibitors. . Molecules, 2015.
    • Quehl PC, Riemer J & Jose J. (). A versatile whole cell biocatalyst by the co-expression of Cytochrome P450 monooxygenases and Cytocrhome P450 reductase on the surface of Escherichia coli. In 19th International Conference on Cytochrome P450, Tokio, Japan.
    • Schüürmann J, Lindhorst F, Jose J . (). P450s for Pharmaceutical applications - a new whole cell biocatalyst by surface display of CYP102A1 via autodisplay. In 19th International Conference on Cytochrome P450, Tokio, Japan.
    • Gratz A, Bollacke A, Stephan S, Nienberg C, Le Borgne M, Götz C, Jose J . (). Functional display of heterotetrameric human protein kinase CK2 on Escherichia coli: a novel tool for drug discovery. Microb Cell Fact, 14, 74.
    • Guragossian N, Gozzi GJ, Bouaziz Z, Winter E, Daflon-Yunes N, Honorat M, Marminon C, Terreux R, Valdameri G, Bollacke A, Guillon J, Pinaud N, Marchivie M, Cadena S, Jose J, Le Borgne M & Di Pietro A. (). Prediction of the physicochemical and ADMET properties of indeno[1,2-b]indole derivatives as potent ABCG2 inhibitors. In Forum de la Recherche en Cancérologie Rhône-Alpes Auvergne, Lyon, Frankreich.
    • Fouillet B, Nacereddine A, Lied LN, Bouaziz Z, Herfindal L, Marminon C, Bollacke A, Døskeland SO, Jose J, Le Borgne M . (). Indeno[1,2-b]indole derivatives as protein kinase CK2 inhibitors: comparison of in silico models for Tox prediction. In Forum de la Recherche en Cancérologie Rhône-Alpes Auvergne,, Lyon, Frankreich.
    • Schmithals C, Bollacke A, Jose J, Wünsch B . (). Syntheses and structure activity relationships of novel CK2 inhibitors with dibenzofuran scaffold. In Frontiers in Medicinal Chemistry" GdCh / DPhG / SCS (Swiss Chemical Society), Marburg, Deutschland.
    • Bopp B, Ciglia E, Ouald-Chaib A, Groth G, Gohlke H & Jose J. (). Development of an autodisplay based screening assay for dimerization inhibitors of human chaperone Hsp90 targeting the C-terminal domain. In DPhG-Doktorandentagung, Biberach, Deutschland.
    • Yoo G, Bong MH, Park M, Jose J, Kang MJ, Pyun JC . (). Electrochemical analysis of autodisplayed adrenodoxin (ADX) on the outer membrane of E. coli. BBA Biomembranes, 1848, 1509–1513.
    • Sichwart S, Tozakidis IE, Teese M & Jose J. (). Maximized autotransporter mediated expression (MATE) of surface display and secretion of recombinant proteins in Escherichia coli. Food Technol Biotech, 53(3), 251–260. doi: 10.17113/ftb.53.03.15.3802.
    • Marminon C, Nacereddine A, Bouaziz Z, Nebois P, Jose J & LeBorgne M. (). Microwave-assisted oxidation of Indan-1-ones into Ninhydrins. Tetrahedron Letters, 2015(56), 1840–1842.
    • Nacereddine A, Bouaziz Z, Marminon C, LeBorgne M & Jose J. (). Improved inhibitors of human kinase protein CK2: Synthesis and biological evaluation of substituted indeno[1,2-b]indole derivatives. In 22nd Young Research Fellow Meeting, Paris.
    • Park M, Yoo G, Bong JH, Jose J, Kang MJ, Pyun J-C . (). Isolation and characterization of the outer membrane of Escherichia coli with autodisplayed Z-domains. Biochim Biophys Acta - Biomembranes, 2015.
    • Kranen E, Rockser Y, Müller B, Jach G, Maas R, Jose J . (). Autodisplay – a powerful tool for the utilization of plan P450 enzymes. . In Biotrans, Wien, Österreich.
    • Uttarkar S, Dassé E, Coulibaly A, Steinmann S, Jakobs A, Schomburg C, Trentmann A, Jose J, Schlenke P, Berdel WE, Schmidt TJ, Müller-Tidow C, Trampton J & Klempnauer KH. (). Targeting acute myeloid leukemia with a small molecule inhibitor of the Myb/p300 interaction. Blood, . Blood, 2015. [accepted / in Press (not yet published)]
    • Tozakidis IE, Sichwart S, Jose J . (). Going beyond E. coli: Autotransporter based surface display on alternative host organisms. New Biotechnol, 32, 644–650.

    • Bopp B, Raaf J, Neundorf I, Niefind K & Jose J. (). Development of a screening assay to identify inhibitors of CK2α/CK2β interaction. In International School of Crystallography, Erice, Sizilien.
    • Orlando Z, Olschewski I, Brossette T, Hensel & Jose J. (). Identification of novel human Hyaluronidase Hyal1 inhibitors from saponine derivatives. . In Forschung der Chemischen Institute (Symposium), Münster.
    • Nacereddine A, Marminon C, Bouaziz Z, Jose J, LeBorgne M . (). Synthesis and biological evaluation of substituted indeno[1,2-b]indole derivatives as inhibitors of human protein kinase CK2. In 18ème Journée Scientifique de l’EDISS, F-Lyon.
    • Park M, Pyun JC, Jose J & Kang MJ. (). Z-domains autodisplaying E. coli for flow cytometry-based immunoassays. In Annual Spring Meeting of the Korean BioChip Society, Seoul, Korea.
    • Weckenbrock W, Blaßhofer F, Klotz L-O, Jose J . (). Bacterial tumor cell targeting using the Autodisplay technology. In DPhG Jahrestagung, Frankfurt, Deutschland.
    • Schüürmann J, Lang K & Jose J. (). Co-factor regeneration via Autodisplay – Towards industrial applications with surface displayed enzymes. In BioCat, Hamburg, Deutschland.
    • Schüürmann J & Jose J. (). Towards Industrial Applications with Surface Displayed Enzymes – Co-factor Regeneration via Autodisplay. In Summer School Biotransformation, Bad Herrenalb, Deutschland.
    • Tozakidis IEP, Meyers A, Jose J . (). Establishing the ethanologenic bacteria Zymomonas mobilis and Zymobacter palmae as platforms for surface display applications. In BioCat, Hamburg, Deutschland.
    • Quehl P, Riemer J, Jose J . (). Surface Display of Cytochrome P450 Reductase and CYP 1A2 on Escherichia coli. In Summer School Biotransformation, Bad Herrenalb.
    • Quehl P, Riemer J, Jose J . (). Combined display of cytochrome P450 reductase and CYP 1A2 on the surface of Escherichia coli. . In BioCat, Hamburg, Deutschland.
    • Sichwart S, Teese MG & Jose J. (). Autodisplay of Burkholderia gladioli carboxylesterase EstA on Pseudomonas putida KT2440. In BioCat, Hamburg, Deutschland.
    • Jose J, Kuckländer U, Gratz A, Bollacke A, Wünsch B, Schmithals C, Schnitzler A, Niefind K & Götz C. (). Developing benzofuranes as CK2 inhibitors in the subnanomolar range: pharmacological and structural biology data. In GP2A XXII, F-Nantes.
    • Orlando Z, Olschewski I, Brossette T, Hensel A, Jose J . (). Autodisplay of human hyaluronidase hyal-1 and identification of new inhibitors among natural compounds. In GP2A XXII, F-Nantes.
    • Schüürmann J, Lang K, Jose J . (). Co-factor regeneration at the cell surface – upgrading the biotechnological potential of whole cell biocatalysts. In European Congress of Biotechnology, Edinburg, Scotland.
    • Quehl P & Jose J. (). Combined surface display of Cytochrome P450 1A2 and its reductase on Escherichia coli . In European Congress of Biotechnology, Edinburg, Scotland.
    • Bong JH, Yoo BG, Park M, Kang MJ, Jose J, Pyun J-C . (). Ultrasonic isolation of the outer membrane of Escherichia coli with autodisplayed Z-domains. Enzyme Microb Tech, 66, 42–47. doi: 10.1016/j.enzmictec.2014.08.006.
    • Tozakidis IEP, Sichwart S, Teese G & Jose J. (). Autotransporter mediated esterase display on Zymomonas mobilis and Zymobacter palmae. J Biotechnol, 191, 228–235.
    • Schüürmann J, Quehl P, Festel G & Jose J. (). Bacterial whole cell biocatalysts by surface display of enzymes: towards industrial application. Appl Microbiol Biotechnol, 98, 8031–8046. doi: 10.1007/s00253-014-5897-y.
    • Bopp B, Ciglia E, Gohlke H, Jose J . (). Protein-protein interaction (PPI) inhibitors of human HSP90 identified by flow cytometer based screening. In Forschung der Chemischen Institute (Symposium), Münster.
    • Park M, Pyun J-C, Jose J & Kang M-J. (). Z-domains autodisplaying E. Coli for flow cytometry-based immunoassays. In Annual Spring Meeting of the Korean BioChip Society, Jeju, Korea.
    • Gawarzewski I, DiMaio F, Winterer E, Tschapek B, Smits SH, Jose J & Schmitt L. (). Crystal structure of the transport unit of the autotransporters adhesion involved in diffuse adherence from Escherichia coli. J Struct Biol, 187, 20–29.
    • Saenger T, Braukmann A, Vordenbäumen S, Altendorfer I, Bleck E, Hochwallner H, Valenta R, Schneider M, Jose J . (). Development of a surface display ELISA to detect anti-IgG antibodies against bovine alphaS1-Casein in human sera. Journal of Pharmaceutical and Biomedical Analysis, 96, 144–150.
    • Bouaziz Z, Samar I, Gentili J, Gratz A, Bollacke A, Kassack M, Jose J, Herfindal L, Gausdal G, Doskeland SO, Mullié C, Sonnet P, Desgrouas C, Taudon N, Valdameri G, Di Pietro A, Baitiche M, Le Borgne M . (). Biologically active carbazole derivatives: focus on oxazinocarbazoles and related compounds. J Enz Inhib Med Chem, accepted. J Enz Inhibit Med Chem, 30, 180–188.
    • Yoo G, Bong JH, Kim S, Jose J, Pyun JC . (). Microarray based on autodisplayed Ro proteins for medical diagnosis of systemic lupus erythematosus (SLE). Biosens Bioelectron, 57, 213–218.
    • Tubeleviciute A, Teese MG, Jose J . (). Escherichia Coli kduD encodes an oxidoreductase that converts both sugar and steroid substrates. Applied Microbiology and Biotechnology, 98, 5471–5485. doi: 10.1007/s00253-014-5551-8.
    • Kranen E, Detzel C, Weber T, Jose J . (). Autodisplay for the co-expression of lipase and foldase on the surface of E. coli: washing with designer bugs. Microbial Cell Factories, 13, 19.
    • Szermerski M, Melesina J, Wichapong K, Löppenberg M, Jose J, Sippl W, Holl R . (). Synthesis, biological evaluation and molecular docking studies of benzyloxyacetohydroxamic acids as LpxC inhibitors. Bioorg Med Chem, 22, 1016–1028.
    • Park M, Bong, JH, Jose J, Kang, MJ, Pyun JC . (). FACS-based immunoassay of troponin-I using E. coli cells with autodisplayed Z-domains. Analytical Methods, 6, 1700–1708.
    • Riemer J, Beckers T, Brossette T & Jose J. (). Autodisplay of human cytochrome P450 enzymes on the cell surfaces of Eschericha coli. In BioCat, Hamburg.

    • Gawarzewski I, DiMaio F, Jose J, Smits SHJ, Schmitt L . (). The crystal structure of the membrane protein AIDA-I from Escherichia Coli. In Biostruct Symposium 2013 Heinrich-Heine-Universität, Düsseldorf , p. 27.
    • Bellof M, Jose J, Brossette T, Dobler N, Maas R . (). Autodisplay of cellulases on the surface of E. coli for the concerted biotransformation of lignocellulose. In 2nd International Symposium on Green Chemistry Renewable carbon and Eco-Efficient Processes, La Rochelle, France,, La Rochelle, Frankreich.
    • Uttarkar S, Goblirsch M, Jose J, Klempnauer KH . (). Development of new assay systems for screening inhibitory molecules of c-Myb. In Proceedings of the 2013 AACR-NCI-EORTC International Conference on Molecular Targets and Cancer Therapeutics.
    • Braukmann A, Vordenbäumen S, Schneider M & Jose J. (). Innovative ELISA-Plattform für flexible Diagnostik. M&K kompakt "Labor und Diagnostik", 10, 22–23.
    • Wessel L, Hoffmann M, Weber F, Düfer M, Hempel G, Hensel A, Jose J, Langer K, Lehr M, Müller K, Schmidt T & Wünsch B. (). PharMSchool. In DPhG annual conference, Freiburg, Deutschland.
    • Weckenbrock W, Blaßhofer F, Jose J . (). Autodisplay of anti-EGFR antibody fragments on Escherichia coli and bacterial tumor cell targeting. . In DPhG annual conference, Freiburg, Deutschland.
    • Löppenberg M, Teese M, Jose J & Holl R. (). Autodisplay of LpxC in Escherichia Coli. In DPhG annual conference, Freiburg, Deutschland.
    • Tubeleviciute A, Teese M, Jose J . (). An oxidoreductase from Escherichia coli catalyzes the regioselective reduction of mineralocorticoids and glucocorticoids in vitro. In DPhG annual conference, Freiburg, Deutschland.
    • Orlando Z, Olschewski I, Brossette T, Jose J . (). Autodisplay of human hyaluronidases PH-20 and Hyal-1 and testing of inhibitors. In DPhG annual conference, Freiburg, Deutschland.
    • Saenger T, Braukmann, A, Vordenbäumen S, Altendorfer I, Bleck E, Hochwallner H, Valenta R, Schneider, S, Jose J . (). Development of a surface display ELISA to detect an IgG-mediated reaction against bovine αS1-casein in human sera. DPhG annual conference. In DPhG annual conference, Freiburg, Deutschland.
    • Altendorfer I, Braukmann A, Saenger T, Bleck E, Vordenbaeumen S, König S, Schneider M, Jose J . (). Mass spectrometric (MS) quantification of αS1-casein (CSN1S1) in breast milk. In DPhG annual conference, Freiburg, Deutschland.
    • Issa S, Bouaziz Z, Gentili J, Gratz A, Bollacke A, Kassack M, Jose J, Herfindal L, Gausdal G, Doskeland SO, Mullié C, Sonnet P, Desgrouas C, Taudon N, Baitiche M, LeBorgne M . (). Oxazinocarbazoles as casein kinase 2 (Ck2) inhibitors, and potent antileukemic and antimalarial moieties. . In ChemBioInteract, Conference on Drug Discovery & Drug Design, Lyon, France.
    • Ettouati L, Alchab F, Fenet B, LeBorgne M, Jose J, Pinaud N, Guillon J & Niemitz M. (). Computer-assisted NMR assignement and conformational analysis of bioactive indeno[1,2-b]indole-10-one derivatives. In Conference on Drug Discovery & Drug Design, Lyon, France.
    • Nacereddine A, Marminon C, Bouaziz Z, Jose J, Bollacke A & LeBorgne M. (). Indeno[1,2-b]indole derivatives as human protein kinase CK2 inhibitors. In Conference on Drug Discovery & Drug Design, Lyon, France.
    • Jose J, Kuckländer U, Gratz A, Bollacke A, Wünsch B, Schnitzler C, Götz C, Schnitzler A, Niefind K . (). Dibenzofuran derivatives as potent and selective inhibitors of human protein kinase CK2. In Conference on Drug Discovery & Drug Design, Lyon, France.
    • Rongved P, Kirsch G, Bouaziz Z, Jose J & LeBorgne M. (). Indenoindoles and cyclopentacarbazoles as bioactive compounds: synthesis and biological applications - A review. Eur J Med Chem, 2013(69C), 465–479.
    • Vordenbäumen S, Braukmann A, Altendorfer I, Bleck E, Jose J & Schneider M. (). Human casein alpha s1 (CSN1S1) skews in vitro differentation of monocytes towards macrophages. BMC Immunology, 2013, 14:46.
    • Al Chab F, Fenet B, LeBorgne M, Jose J, Ettouati L, Pinaud N & Guillon J. (). 1H and 13C NMR assignments of bioactive indeno[1,2-b]indole-10-one derivatives. Magn Reson Chem, 2013. doi: 10.1002/mrc.4016.
    • Jana SK, Löppenberg M, Daniliuc CG, Jose J & Holl R. (). Development of novel LpxC inhibitors: chiral-pool synthesis of C-triazolyl glycosides. Tetrahedron, 2013.
    • Bopp B, Raaf J, Neundorf I, Niefind K, Jose J . (). Development of a flow cytometry based screening to identify inhibitors of CK2a/CK2b interaction. In 7th International Conference of Protein kinase CK2, Lublin, Polen.
    • Nienberg C, Reicheneder C, Bollacke A, Gratz A, Jose J . (). Identification of novel peptidic inhibitors of human protein kinase CK2 by surface display library screening. In 7th International Conference of Protein kinase CK2, Lublin, Polen.
    • Bollacke A, Al Chab F, Ettouati L, Bouaziz Z, Delcros J-G, Gertzen C, Gohlke H, Fenet B, Le Borgne M, Jose J . (). Novel substituted indeno[1,2-b]indoles as inhibitors of the human protein kinase CK2. In 7th International Conference of Protein kinase CK2, Lublin, Polen.
    • Quehl P, Riemer J, Jose J . (). Surface Display of Cytochrome P450 Reductase on Escherichia coli. In Horizons in Molecular Biology 2013, Göttingen.
    • Schüürmann J & Jose J. (). Cell Surface based NADPH Regeneration via Autodisplay. In Horizons in Molecular Biology 2013, Göttingen.
    • Tozakidis, IA, Sichwart S & Jose J. (). Surface display of an active esterase on Zymomonas mobilis cells using the Autodisplay technology. In Horizons in Molecular Biology 2013, Göttingen.
    • Orlando Z, Olschewski I, Brossette T, Jose J . (). Plant-derived inhibitors of human hyaluronidases. In 61st International Congress and Annual Meeting of the Society for Medicinal Plant and Natural Product Research, Münster.
    • Gawarzewski I, Tschapek B, Hoeppner A, Jose J, Smits S, Schmitt L . (). Purification, crystallization and preliminary X-ray crystallographic studies of the transport unit of the monomeric autotransporter AIDA-I from Escherichia coli. Acta Crystallographica. Section F: Structural Biology and Crystallization Communications, 2013, 1159–1162.
    • Rongved P, Kirsch G, Bouaziz Z, Jose J, LeBorgne M . (). Indenoindoles and cyclopentacarbazoles as bioactive compounds: synthesis and biological applications - A review. Eur J Med Chem, 2013.
    • Ölgen S, Gratz A, Kurt ZK & Jose J. (). N-substituted indole-2 and 3-carboxamide derivatives as inhibitors of human protein kinase CK2: in vitro assay and molecular modeling study. Acta Chim Slov, 2013(60), 628–635.
    • Gawarzewski I, Smits SHJ, Schmitt L, Jose J . (). Structural comparison of the transport units of type V secretion systems. Journal of Biological Chemistry, 394, 1385–1398.
    • Oh J, Yoo G, Chang YW, Kim HJ, Jose J, Kim E, Pyun JC & Yoo K-H. (). A carbon nanotube metal semiconductor field effect transistor-based biosensor for detection of amyloid-beta in human serum. Biosens Bioelectron, 2013(50), 345–350.
    • Löppenberg M, Müller H, Pulina C, Oddo A, Teese MG, Jose J, Holl R . (). Synthesis and biological evaluation of flexible and conformationally constrained LpxC inhibitors. Organic and Biomolecular Chemistry, 2013(11), 6056–6070. doi: 10.1039/C3OB41082J.
    • Park M, Bong JH, Yoo G, Jose J, Kang MJ & Pyun JC. (). Optimization of a FACS based-immunoassay using E. coli autodisplaying Z-domains. Biochip Journal, 7, 173–179. doi: 10.1007/s13206-013-7211-y.
    • Raaf J, Guerra B, Neundorf I, Bopp B, Issinger O-G, Jose J, Pietsch M, Niefind N . (). First structure of protein kinase Ck2 catalytic subunit with an effective CK2β-competitive ligand. ACS Chemical Biology, 8, 901–907. doi: 10.1021/cb3007133.
    • Guillon J, Le Borgne M, Rimbault C, Moreau S, Savrimoutou S, Pinaud N, Marchivie M, Bollacke A, Pecci A, Alvarez, Desplat V, Jose J . (). Synthesis and biological evaluation of novel substituted pyrrolo[1,2- α]quinoxaline derivatives as inhibitors of the human protein kinase CK2. European Journal of Medicinal Chemistry, 65, 205–222.
    • Park M, Bong JH, Yoo G, Jose J, Kang MJ, Pyun JC . (). Flow cytometric immunoassay using E. coli with autodisplayed Z-domains. Enzyme Microb Tech, 2013(53), 181–188.
    • Yoo G, Park M, Bong JH, Jose J, Pyun JC . (). Magnetic-beads-based immunoassay using E. coli cells with autodisplayed Z-domains. Enzyme Microb Tech, 2013(53), 118–122.
    • Löppenberg M, Teese M, Jose J & Holl R. (). Development of a LpxC enzyme Assay for inhibitor testing. In Frontiers in Medicinal Chemistry, Munich.
    • Detzel C, Maas R, Tubeleviciute A, Jose J . (). Autodisplay of nitrilase from Klebsiella pneumoniae and whole-cell degradation of oxynil herbicides and related compounds. Appl Microbiol Biotechnol, 97, 4887–4896. doi: 10.1007/s00253-012-4401-9.
    • Jose, Joachim. (). Ausdrucksstark. q&more, 1, 12–17.
    • Kranen E, Rockser Y, Maas R, Jose J . (). Autodisplay – a new biocatalytical approach for challenging enzymes and interacting proteins. . In Biotrans, Manchester, UK.

    • Götz C, Gratz A, Kucklaender U, Jose J . (). TF – a novel cell-permeable and selective inhibitor of human protein kinase CK2 induces apoptosis in the prostate cancer cell line LNCaP. Biochimica et Biophysica Acta - General Subjects, 2012(1820), 970–977. doi: 10.1016/j.bbagen.2012.02.009.
    • Petermann K, Vordenbäumen S, Maas R, Braukmann A, Bleck E, Saenger T, Schneider M & Jose J. (). Autoantibodies to alphaS1-casein are induced by breast-feeding. PloS one, 2012(7), e32716. doi: 10.1371/journal.pone.0032716.
    • Gratz A, Götz C, Kuckländer U, Jose J . (). Discovery of selective and cell-permeable inhibitors of CK2, inducing apoptosis in cancer cells. In Forschung der Chemischen Institute (Symposium), Münster.
    • Schumacher S, Teese M, Hannemann F, Bernhardt R, Jose J . (). Autodisplay of P450 monooxygenase for the conversion of testosterone, desoxycorticosterone, imipramine and abietic acid. In Forschung der Chemischen Institute (Symposium), Münster.
    • Kranen E, Maas R, Jose J . (). Let me be your chaperone – Autodisplay for the co-expression of lipase and its chaperone foldase from Burkholderia cepacia. In Dechema-Tagung, Düsseldorf.
    • Kranen E, Fiebig M, Brossette, Maas R, Jose J . (). Utilization of cytochrome P450 enzymes by Autodisplay. In 6th International Congress on Biocatalysis, Hamburg.
    • Tubeleviciute A, Teese MG & Jose J. (). Discovery of a novel bacterial steroid dehydrogenase. In 6th International Congress on Biocatalysis, Hamburg.
    • Schumacher SD, Teese MG, Hannemann F, Bernhardt R, Jose J . (). Autodisplay of functional P450 monooxygenases. In 6th International Congress on Biocatalysis, Hamburg.
    • Braukmann A, Petermann K, Vordenbäumen S, Maas R, Bleck E, Saenger T, Schneider M, Jose J . (). Autoantibodies to alphaS1 Casein are induced by breast-feeding. In XXIInd International Symposium on Medicinal Chemistry, Berlin.
    • Bopp B, Ciglia E, Gohlke H, Jose J . (). Autodisplay of the human chaperone HSP90 and development of an inhibitor assay. In XXIInd International Symposium on Medicinal Chemistry, Berlin.
    • Orlando Z, Kaeßler A, Hundsdörfer C, Müller K & Jose J. (). Autodisplay of human hyaluronidase PH-20 and testing of inhibitors. In XXIInd International Symposium on Medicinal Chemistry, Berlin.
    • Bollacke A, Hundsdörfer C, Gratz A, Jose J . (). Autodisplay of human protein kinase CK2 for inhibitor testing. In XXIInd International Symposium on Medicinal Chemistry, Berlin.
    • Reicheneder C, Gratz A, Jose J . (). Identification of a peptidic non-ATP competitive inhibitor of human CK2 by bacterial surface display library screening. In XXIInd International Symposium on Medicinal Chemistry, Berlin.
    • Reicheneder C, Gratz A & Jose J. (). Bacterial surface display library screening for the identification of potent non-ATP-competitive CK2 inhibitors. In DPhG-Doktorandentagung, Weimar.
    • Goblirsch M, Gratz A & Jose J. (). Comparing Tat- and Sec-mediated autodisplay of GFP. In DPhG-Doktorandentagung, Weimar.
    • Lee EH, Yoo G, Jose J, Kang MJ, Song SM & Pyun JC. (). SPR biosensor on immobilized E. coli cells with autodisplayed Z-domains. Biochip J, 2013(6), 221–228. doi: 10.1007/s13206-012-6304-3.
    • Perret F, Marminon C, Zeinyeh W, Nebois P, Bollacke A, Jose J, Parrot-Lopez H, Le Borgne M . (). Preparation and characterization of CK2 inhibitor-loaded cyclodextrin nanoparticles for drug delivery. International Journal of Pharmaceutics, 2013(441), 491–498. doi: 10.1016/j.ijpharm.2012.11.004.
    • Hundsdörfer C, Hemmerling HJ, Hamberger J, Le Borgne M, Bednarski P, Götz C, Totzke F & Jose J. (). Novel indeno[1,2-b]indoloquinones as inhibitors of the human protein kinase CK2 with antiproliferative activity towards a broad panel of cancer cell lines. Biochemical and Biophysical Research Communications, 2012(424), 71–75. doi: 10.1016/j.bbrc.2012.06.068.
    • Jose J, Maas RM & Teese MG. (). Autodisplay of enzymes - molecular basis and perspectives. Journal of Biotechnology, 2012(161), 92–103. doi: 10.1016/j.jbiotec.2012.04.001.
    • Schumacher SD, Hannemann F, Teese MG, Bernhardt R & Jose J. (). Autodisplay of functional CYP106A2 in Escherichia coli. Journal of Biotechnology, 2012(161), 104–112. doi: 10.1016/j.jbiotec.2012.02.018.
    • Hundsdörfer C, Hemmerling HJ, Götz C, Bednarski P, Le Borgne M & Jose J. (). Indeno[1,2-b]indole derivatives as a novel class of potent human protein kinase CK2 inhibitors. Bioorganic and Medicinal Chemistry, 2012(20), 2282–2289. doi: 10.1016/j.bmc.2012.02.017.
    • Schumacher SD & Jose J. (). Expression of active human P450 3A4 on the cell surface of Escherichia coli by Autodisplay. Journal of Biotechnology, 2012(161), 113–120. doi: 10.1016/j.jbiotec.2012.01.031.
    • Lee JK, Yoo G, Park M, Jose J, Kang MJ & Pyun JC. (). Electrochemial ELISA based on Escherichia coli with autodisplayed Z-domains. Sensors and Actuators B: Chemical, 2012(175), 46–52. doi: 10.1016/j.snb.2011.11.064.

    • Ölgen S, Kaessler A, Kiliç Kurt Z & Jose J. (). Structure-activity evaluation of N-benzyl-5-substituted indole-3-imine derivatives and their amine congeners as bovine testicular Hyaluronidase (BTH) inhibitor. Letters in Drug Design and Discovery, 8(8), 685–690. doi: 10.2174/157018011796576079.
    • Vordenbäumen S, Petermann K, Braukmann A, Bleck E, Jose J, Schneider S . (). Casein α s1 Is Expressed by Human Monocytes and Upregulates the Production of GM-CSF via p38 MAPK. The Journal of Immunology, 186(1), 592–601. doi: 10.4049/jimmunol.1001461.
    • Kaeßler A, Olgen S, Jose J . (). Autodisplay of catalytically active human hyaluronidase hPH-20 and testing of enzyme inhibitors. European Journal of Pharmaceutical Sciences, 42(1-2), 138–147. doi: 10.1016/j.ejps.2010.11.004.
    • Park M, Jose J, Thömmes S, Kim J, Park MJ, Pyun JC . (). Autodisplay of streptavidin. . Enzyme and Microbial Technology, 48(4-5), 307–311. doi: 10.1016/j.enzmictec.2010.12.006.
    • Kucklaender U, Bollig R, Frank W, Gratz A, Jose J . (). A novel application of DDQ as electrophile in the Nenitzescu reaction. Bioorganic and Medicinal Chemistry, 19(8), 2666–2674. doi: 10.1016/j.bmc.2011.03.006.
    • Detzel C, Maas R, Jose J . (). Autodisplay of nitrilase from Alcaligenes faecalis in E. coli yields a whole cell biocatalyst for the synthesis of enantiomerically pure (R)-mandelic acid. ChemCatChem, 3(4), 719–725. doi: 10.1002/cctc.201000382.
    • Park M, Jose J, Pyun JC . (). SPR biosensor by using E. coli outer membrane layer with autodisplayed Z-domains. Sensors and Actuators B: Chemical, 154(2), 82–88. doi: 10.1016/j.snb.2010.03.039.
    • Kranen E, Steffan N, Maas RM, Li SM, Jose J . (). Development of a whole cell biocatalyst for the efficient prenylation of indole derivatives by Autodisplay of the aromatic prenyltransferase FgaPT2. ChemCatChem, 3(7), 1200–1207. doi: 10.1002/cctc.201000429.
    • Gratz A, Bollig R, Kuckländer U, Götz C, Jose J . (). Identification of novel CK2 inhibitors with a benzofuran scaffold by novel non-radiometric in vitro assays. Molecular and Cellular Biochemistry, 2011(356), 1-2–83. doi: 10.1007/s11010-011-0957-4.
    • Gratz A, Jose J . (). Focussing mutations to defined domains: protein domain library generation by overlap extension (PDLGO). . In Lu, Browse, Wallis (Eds.), Methods in Molecular Biology (pp. 153–166). London: Humana Press.
    • Yoo G, Park M, Lee EH, Jose J, Pyun JC . (). Immobilization of E. coli with autodisplayed Z-domains to a surface-modified microplate for immunoassay. Analytica Chimica Acta, 2011(707), 142–147. doi: 10.1016/j.aca.2011.09.004.
    • al Chab F, Marminon C, Bouaziz Z, Ettouati L, Gentili J, Nebois P, Gratz A, Hundsdörfer C, Jose J, Le Borgne M . (). Optimization of biomolecules targeting Protein Kinase CK2. In 16ème Journée Scientifique de l’EDISS – Ecole Doctorale Interdisciplinaire Sciences Santé, Lyon.
    • Schumacher S, Hannemann F, Bernhardt R, Jose J . (). Functional display of CYP106AZ and CAP3A4 on Escherichia coli. . In 2nd CLIB International Conference, Düsseldorf.
    • Tubeleviciute A, Jose J . (). Autodisplay of an E. coli steroid C-20 dehydrogenase for regioselective reduction of steroidal compounds . In 2nd CLIB International Conference Retreat, Bonn.
    • Schumacher S, Hannemann F, Bernhardt R, Jose J . (). Surface display and activity measurements of P450 enzymes in E. coli. In 2nd CLIB International Conference Retreat, Bonn.
    • Park M, Pyun JC, Jose J . (). Autodisplay Outer membrane layers for immuno-affinity biosensor. In Muenster Symposion on Cooperative effects in chemistry, Münster.
    • Park M, Pyun JC, Thömmes S, Jose J . (). Outer membrane preparations with autodisplayed streptavidin for immobilization of biotinylated peptides or proteins. In Muenster Symposion on Cooperative effects in chemistry, Münster.
    • Park M, Jose J, Pyun JC . (). Autodisplay Technology for high sensitive immunoassay. In ISMM The International Symposium on Microchemistry and Microsystems, Seoul.
    • Park M, Jose J, Pyun J . (). Immuno-affinity biosensor by using the autodisplay technology. In Affinity 2011, 19th biennal Meeting of the Intern. Society for Molecular Recognition, Tavira.
    • Detzel C, Festel G, Maas R, Jose J . (). Autodisplay – a new biocatalytic approach for challenging enzymes. In RRB7, Bruges.
    • Gawarzewski I, Jose J, Tschapek B, Smits SHJ, Schmitt L . (). Purification and crystallization of the AIDA-I ß-barrel in the outer membrane of E. coli. In 2nd BioStruct MasterClaas “Macromolar Interactions”, Düsseldorf.
    • Gawarzewski I, Jose J, Tschapek B, Smits SHJ, Schmitt L . (). Purification and crystallization of the AIDA-I ß-barrel in the outer membrane of E. coli. In Molecular Life Sciences, Frankfurt.
    • Yoo G, Park M, Lee JK, Lee EH, Jose J & Pyun JC. (). Fluorescence immunoassay based on E. coli with autodisplayed Z-domains by using flow cytometry (FACS). In 2nd International Conference on Bio-Sensing Technology, Amsterdam.
    • Lee JK, Yoo G, Park M, Jose J, Kang MJ & Pyun JC. (). Electrochemical ELISA based on E. coli with autodisplayed Z-domains. Procedia Engineering, 2011(25), 944–947.

    • Braukmann A, Petermann K, Bleck E, Schneider M, Jose J . (). Autodisplay of 60 kDa Ro/SS-A and development of a new ELISA for SLE patient sera screening. In DPhG Jahrestagung, Braunschweig.
    • Maas R, Jose J Festel G . (). Autodisplay: new approaches for biocatalysis, drug discovery and bioanalytics. In DECHEMA Jahrestagung der Biotechnologen, Aachen.
    • Gratz A, Goetz C, Jose J . (). A FRET-based microplate assay for human protein kinase CK2, a target in neoplastic disease. Journal of Enzyme Inhibition and Medicinal Chemistry, 25(2), 234–239. doi: 10.3109/14756360903170038.
    • Jose J, Park M, Pyun JC . (). E. coli outer membrane with autodisplayed Z-domain as a molecular recognition layer of SPR biosensor. Biosensors and Bioelectronics, 25(5), 1225–1228. doi: 10.1016/j.bios.2009.09.025.
    • Gratz A, Götz, C, Jose J . (). A CE-based method for human protein kinase CK2 activity measurement and inhibitor screening. Electrophoresis, 31(4), 634–640. doi: 10.1002/elps.200900514.
    • Park M, Jose J, Pyun JC . (). Hypersensitive immunoassay by using Escherichia coli outer membrane with autodisplayed Z-domains. . Enzyme and Microbial Technology, 46(3-4), 309–314. doi: 10.1016/j.enzmictec.2009.12.004.
    • Bouaziz Z, Issa S, Jose J, Gratz A, Götz C, Di Pietro A, Falson P, Arnaud O & Le Borgne M. (). Targeting Casein Kinase 2 in Drug Discovery: Identification of New Chemical Entities. . Bulletin du Cancer, 97(SI), S68–S69.
    • Jose J, Park M, Pyun JC . (). Highly sensitive immunoassay based on E. coli with autodisplayed Z-domain. Analytica Chimica Acta, 667(1-2), 113–118. doi: 10.1016/j.aca.2010.03.046.
    • Kiliç-Kurt Z, Kaeßler A, Jose J, Olgen S . (). Investigation of Aminomethyl Indole Derivatives as Hyaluronidase Inhibitors. Zeitschrift für Naturforschung C - A Journal of Biosciences, 65(7-8), 445–450.
    • Petermann K, Vordenbäumen S, Pyun JC, Braukmann A, Bleck E, Schneider S & Jose J. (). Autodisplay of 60-kDa Ro/SS-A antigen and development of a surface display enzyme-linked immunosorbent assay for systemic lupus erythematosus patient sera screening. Analytical Biochemistry, 407(1), 72–78. doi: 10.1016/j.ab.2010.07.030.
    • Maas R, Jose J, Festel G . (). Autodisplay Biotech: Neue Lösungen für Biokatalyse, Drug Discovery und Bioanalyse. Chemie Ingenieur Technik, 82(9), 1520–1521. doi: 10.1002/cite.201050480.
    • Kaeßler A, Hundsdörfer C, Olgen S, Jose J . (). Autodisplay of catalytically active human hyaluronidase hPH-20 in E. coli and testing of enzyme inhibitors. In Frontiers in Medicinal Chemistry, Münster.
    • Bouaziz Z, Issa S, Jose J, Gratz A, Götz C, DiPietro A, Falson P, Arnaud O, Le Borgne M . (). Targeting Casein Kinase 2 in Drug Discovery: Identification of New Chemical Entities. In 5èmes Journées Scientifiques du CLARA, Lyon.
    • Detzel C, Maas R & Jose J. (). Autodisplay of Nitrilase from Alcaligenes faecalis Yields a Whole-cell Biocatalyst for Enantioselective R-Mandelic Acid Production. In biocat2010 5th International Congress on Biocatalysis, Hamburg.
    • Kranen E, Maas R Jose J . (). A Whole-cell Biocatalyst Approach on Cofactor Regeneration by Autodisplay of NADH-Oxidase. In biocat2010 5th International Congress on Biocatalysis, Hamburg.
    • Marminon C, Nebois P, Gratz A, Kassack M, Jose J & Le Borgne, M. (). Exploring new scaffolds for CK2 inhibitory activity: two case studies. In XIXth European Conference of GP2A, Rouen.
    • Gratz A, Götz C, Kuckländer U & Jose J. (). Identification of a benzofuranone derivative as powerful inhibitor of CK2 and its effect on apoptosis. In 6th International Conference on Protein Kinase CK2, Köln.
    • Gratz A, Bollig R, Kuckländer U, Jose J . (). Benzofuran derivatives as attractive CK2 inhibitors. In 6th International Conference on Protein Kinase CK2, Köln.
    • Gratz A, Götz C, Jose J . (). Towards the development of non-radiometric in vitro assays for protein kinase CK2. In 6th International Conference on Protein Kinase CK2, Köln.
    • Hundsdörfer C, Hemmerling H-J, Götz C, Jose J . (). A series of indeno-indole derivatives with potent inhibitory activity towards human protein kinase CK2. In 6th International Conference on Protein Kinase CK2, Köln.
    • Gratz A, Götz C, Kuckländer U, Jose J . (). Benzofuranone TF inhibits protein kinase CK2 and shows pro-apoptotic effects in prostate cancer cells. In DPhG Jahrestagung, Braunschweig.
    • Gawarzewski I, Jose J . (). Overexpression of the His-tagged AIDA-I β-barrel in the outer membrane of E. coli. In Biostruct´s Master Class 2010, Düsseldorf.
    • Kaeßler A, Hundsdörfer C, Olgen S, Jose J . (). Autodisplay of human hyaluronidase hPH-20 yields an active enzyme for the degradation of hyaluronic acid. In 28. DECHEMA-Jahrestagung der Biotechnologen, Aachen.
    • Schumacher S, Hannemann F, Bernhardt R, Jose J . (). Autodisplay of functional P450 enzymes in Escherichia coli. In DECHEMA Jahrestagung der Biotechnologen, Aachen.
    • Thömmes S, Blasshofer F, Jose J . (). Construction and surface display of antibody libraries in E.coli using autodisplay. In Dechema Jahrestagung der Biotechnologen, Aachen.
    • Detzel C, Maas R & Jose J. (). Enantioselective conversion of mandelonitrile to R-mandelic acid using a whole cell biocatalyst obtained by autodisplay of Nitrilase. In Dechema Jahrestagung der Biotechnologen, Aachen.
    • Thömmes S, Blasshofer F, Jose J . (). Autodisplay of combinatorial antibody libraries in E. coli. In DPhG Jahrestagung, Braunschweig.
    • Schumacher S, Hannemann F, Bernhardt R, Jose J . (). Autodisplay of CYP106A2 and CYP3A4 in Escherichia coli. In DPhG Jahrestagung, Braunschweig.
    • Hundsdörfer C, Chapuis A, Rollet A, Bouaziz Z, Le Borgne M, Hemmerling H-J, Claudia Götz & Jose J. (). Indeno[1,2-b]indole derivatives are competitive inhibitors of the human protein kinase CK2. In DPhG-Jahrestagung, Braunschweig.
    • Jose J, Gratz A, Götz C . (). Capillary Electrophoresis (CE) and FRET as tools for testing inhibitors of human protein kinase CK2. In DPhG Jahrestagung, Braunschweig.
    • Kranen E, Völker T, Maas R, Jose J . (). Autodisplay of NADH-Oxidase Yields a Convenient System for Cofactor Regeneration. In DPhG Jahrestagung, Braunschweig.

    • Betscheider D, Jose J . (). Nile Blue A for staining Escherichia coli in flow cytometer experiments. Analytical Biochemistry, 384(1), 194–196. doi: 10.1016/j.ab.2008.09.018.
    • Jose J, Chung JW, Jeon JB, Maas RM, Nam CH, Pyun JC . (). Escherichia coli with autodisplayed Z-domain of protein A for signal amplification of SPR biosensensor. . Biosensors and Bioelectronics, 24(5), 1324–1329. doi: 10.1016/j.bios.2008.07.067.
    • Park M, Jose J, Pyun JC . (). E. coli outer membrane with autodisplayed Z-domain as a molecular recognition layer of SPR biosensor. Procedia Chem, 10(1), 1475–1478. doi: 10.1016/j.proche.2009.07.368.
    • Park M, Jose J, Pyun JC . (). E. coli outer membrane with autodisplayed Z-domain as a molecular recognition layer of SPR biosensor. In Eurosensors XXIII, Lausanne.
    • Gratz A, Götz C, Jose J . (). A novel in vitro assay for human protein kinase CK2 inhibitors based on capillary electrophoresis with UV detection. In XVIIIth European Conference of GP2A, Dublin.
    • Kaeßler A, Olgen S, Jose J . (). Autodisplay of human hyaluronidases in E. coli and development of a microplate assay for inhibitor testing at pH 7 and pH 3.5. In DPhG Jahrestagung, Jena.
    • Brossette T, Jose J, Stahl W . (). The cardioprotective effects of (-)-epicatechin are attributed to the modulation of the L-arginine metabolism in endothelial cells. In DPhG-Doktorandentagung, Pichlarn.
    • Kaeßler A, Olgen S, Jose J . (). Surface display of human hyaluronidases by Autodisplay in E. coli and development of a microplate assay using whole cells for screening of potential hyaluronidase inhibitors. In DPhG-Doktorandentagung, Pichlarn.
    • Gratz A, Götz C & Jose J. (). Development of a CE based assay for evaluation of human protein kinase Ck2 inhibitors. In DPhG Doktorandentagung, Pichlarn.
    • Detzel C, Maas R, Jose J . (). Autodisplay of the nitrilase from Alcaligenes faecalis ATCC 8750 yields a whole cell biocatalyst for the synthesis of enantiomerically pure R-mandelic acid. In DPhG-Doktorandentagung, Pichlarn.
    • Kiliç Z, Kaeßler A, Jose J & Olgen S. (). Evaluation of new N-, C3 and C5 substituted indole derivatives as hyaluronidase Inhibitors. In 1st Turkish-Russian Joint Meeting On Organic and Medicinal Chemistry, Antalya.
    • Gratz A, Götz C & Jose J. (). A non-radiometric inhibitor test for human protein kinase CK2 based on capillary electrophoresis with UV detection. In DPhG Jahrestagung, Jena.
    • Petermann K, Bleck E, Schneider M, Jose J . (). A new whole cell ELISA for screening sera from SLE patients by Autodisplay of 60 kDa Ro/SS-A in E. coli. In DPhG-Doktorandentagung, Pichlarn.
    • Kiliç Z, Kaeßler A, Jose J, Ölgen S . (). Investigation on the hyaluronidase inhibitory activity of aminomethyl indole derivatives. In 1st Turkish-Russian Joint Meeting On Organic and Medicinal Chemistry,, Antalya.
    • Jose J. (). Bioanalytics in medicinal chemistry: from assay development to evolutive drug design. Annales Pharmaceutiques Francaises, 67(6), 399–407. doi: 10.1016/j.pharma.2009.07.002.

    • Olgan S, Götz C, Jose J . (). Synthesis and biological evaluation of 3-(Substituted-benzylidene)-1, 3-dihydro-indolin derivatives as human protein kinase CK2 and p60c-Src tyrosine kinase inhibitors. Biological and Pharmaceutical Bulletin, 309(4), 715–718. doi: 10.1248/bpb.30.715.
    • Hannemann F, Bernhardt R, Jose J . (). Biocatalytic synthesis of 4-pregnen-20,21-diol-3-one, a selective inhibitor of human 5α-reductase type II. Journal of Enzyme Inhibition and Medicinal Chemistry, 224(5), 570–576. doi: 10.1080/14756360701425311.
    • Kaessler A, Algül Ö, Jose J . (). A Microplate based Screening of Benzimidazole Derivatives on Hyaluronidase Inhibition at PH 7 and 3.5 . Letters in Drug Design and Discovery, 4(8), 562–569. doi: 10.2174/157018007782794491.
    • Olgen S, Kaessler A, Nobioglu D, Jose J . (). New potent indole derivatives as hyaluronidase inhibitors. Chemical Biology and Drug Design, 70(6), 547–551. doi: 10.1111/j.1747-0285.2007.00590.x.
    • Blasshofer F, Klotz LO, Sauerbier E, Jose J . (). Tumour cell targeting by cells of E. coli displaying fucntional single chain and “twin chain” antibody fragments against EGFR. . In Frontiers in Medicinal Chemistry. Joint GDCH and DPhG Spring Meeting, Berlin.
    • Kaeßler A, Algül Ö, Jose J . (). A Microtiter plate assay for screening of potential hyaluronidase inhibititors. In Pre-Satellite Meeting of the 3rd Pharmaceutical Science World Congress, Amsterdam.
    • Winterer E, Schultheiss E, Weiss S, Maas R, Heinzle E & Jose J. (). Esterase autodisplay: enzyme engineering and whole cell activity determination by microplates with pH-sensors. In Pre-Satellite Meeting of the 3rd Pharmaceutical Science World Congress, Amsterdam.
    • Jose J, Gratz A . (). Ein neues Werkzeug für die gerichtete Evolution von Proteindomänen: Protein Domain Library Generation by Overlap Extension (PDLGO). . In Tag des wissenschaftlichen Nachwuchses, Heinrich-Heine-Universität, Düsseldorf.
    • Blasshofer F, Klotz LO, Jose J . (). Targeting von Tumorzellen durch E. coli . In Tag des wissenschaftlichen Nachwuchses, Heinrich-Heine-Universität, Düsseldorf.
    • Kaeßler A, Jose J . (). Autodisplay humaner Hyaluronidasen und Entwicklung eines Mikrotiterplattenassays zur Testung von Enzyminhibitoren . In Tag des wissenschaftlichen Nachwuchses, Heinrich-Heine-Universität, Düsseldorf.
    • Petermann K, Schneider M, Iking-Konnert C, Bleck E, Jose J . (). Autodisplay eines Rheuma-assoziierten Antigens an der Oberflächen von E. coli und drauf basierende Etablierung eines Ganzzell-ELISA zum Screening von Patientenseren. . In Tag des wissenschaftlichen Nachwuchses,, Düsseldorf.
    • Hemmerling HJ, Götz C, Jose J . (). Potent inhibitors of human protein kinase CK2 obtained by a novel route for the synthesis of indeno[1,2-b]indoles. In 16èmes Conférences Européennes du GP2A, Bordeaux.
    • Kaessler A, Olgen S & Jose J. (). Development of novel microtiter plate assays enables high-throughput screening of potential hyaluronidase inhibitors. In 16èmes Conférences Européennes du GP2A, Bordeaux.
    • Petermann K, Schneider M, Iking-Konnert C, Bleck E, Jose J . (). A whole cell ELISA to screen rheumatoid arthritis patient sera for antibodies against a newly identified autoantigene. In 16èmes Conférences Européennes du GP2A, Bordeaux.
    • Olgen S, Kaessler A, Jose J, Varol P, Nebioglu D . (). New potent indole derivatives as hyaluronidase inhibitors. In 3rd International Meeting on Medicinal and Pharmaceutical Chemistry,, Antalya.
    • Algul O, Kaessler A, Jose J . (). Synthesis of a series of benzimidazole derivatives and testing on inhibition of hyaluronidase in a microtiter plate assay. 3rd International Meeting on Medicinal and Pharmaceutical Chemistry. In IMPPC-3, Antalya.
    • Jose J & Meyer TF. (). The autodisplay story - from discovery to biotechnical and biomedical applications. Microbiology and Molecular Biology Reviews, 2007(71), 600–619. doi: 10.1128/MMBR.00011-07.

    • Hussein SA, Hashim AN, Barakat HH, Jose J, Lindequist U & Nawwar MA. (). Phenolics from extracts of Brahea armata with inhibitory effect against 5 alpha-reductase type-II. Pharmazie, 61(12), 1034–1037.
    • Winterer E, Schu M, Scheidig A, Jose J . (). Structural and functional investigations on the transport domains of the Autodisplay system. In DPhG Doktorandentagung, Nürnberg.
    • Blasshofer F, Jose J . (). Functional autodisplay of variable antibody fragments in Escherichia coli. In DPhG Doktorandentagung, Nürnberg.
    • Kaessler A & Jose J. (). Cell surface expression of human hyaluronidases in E. coli using the Autodisplay system. In DPhG Doktorandentagung, Nürnberg.
    • Gratz A, Jose J . (). A new method for directed evolution: Protein domain library generation by overlap extension (PDLGO). In DPhG Doktorandentagung, Nürnberg.
    • Hemmerling HJ, Götz C & Jose J. (). A series of indenoindole derivatives with potent inhibitory activity towards human protein kinase CK2. In DPhG Jahrestagung, Marburg.
    • Kaessler A, Jose J . (). Autodisplay of human hyaluronidases Hyal1 and PH20 in Escherichia coli. . In DPhG Jahrestagung, Marburg.
    • Gratz A, Jose J . (). PDLGO: a novel tool for directed evolution of protein domains. In DPhG Jahrestagung, Marburg.
    • Blasshofer F, Jose J . (). Autodisplay of variable fragments of different antibodies in E. coli. In DPhG Jahrestagung, Marburg.
    • Olgan S, Götz C, Jose J . (). Synthesis of 3-(substituted-benzylidene)-1, 3-dihydro-indolin derivatives and investigation of their roles against human protein kinase CK2. In 232nd ACS National Meeting, San Francisco.
    • Jose J. (). Autodisplay: efficient bacterial surface display of recombinant proteins. Applied Microbiology and Biotechnology, 2006(69), 607–614.

    • Winterer E, Müller E, Weiss S, Heinzle E, Jose J . (). Autodisplay und Entwicklung maßgeschneiderter Esterasen. . In Tag des wissenschaftlichen Nachwuchses, Heinrich-Heine-Universität Düsseldorf, Düsseldorf , S. 126.
    • Panter BU, Jose J, Hartmann RW . (). 5alpha-reductase in human embryonic kidney cell line HEK293: Evidence for type II enzyme expression and activity. Molecular and Cellular Biochemistry, 270(1-2), 201–208. doi: 10.1007/s11010-005-4508-8.
    • Jose J & Zangen D. (). Autodisplay of the protease inhibitor aprotinin in Escherichia coli. . Biochemical and Biophysical Research Communications, 333(4), 1218–1226. doi: 10.1016/j.bbrc.2005.06.028.
    • Jose J, Betscheider D & Zangen D. (). Bacterial Surface Display Library Screening by target enzyme labelling: Identification of New Human Cathepsin G Inhibitors. Analytical Biochemistry, 346(2), 258–267. doi: 10.1016/j.ab.2005.08.019.
    • Jose J, Müller E, Heinzle E, Weiss S, Winterer E . (). Autodisplay for the rational and evolutive design of esterases. In Frontiers in medicinal chemistry, Leipzig.
    • Jose J, Bernhardt R, Hannemann F . (). A whole cell biocatalyst for the P450-mediated steroid conversion obtained by Autodisplay of bovine adrenodoxin and chemical incorporation of the (2Fe-2S) Cluster. In Frontiers in medicinal chemistry, Leipzig.
    • Betscheider D, Ray, S, Lengauer T, Jose J . (). Darstellung von Peptidbibliotheken an der Oberfläche von E. coli und Protein-Peptid Docking zur Entwicklung neuer Inhibitoren von Cathepsin G. . In Tag des wissenschaftlichen Nachwuchses, Heinrich-Heine-Universität Düsseldorf, Düsseldorf , S. 24.
    • Hussein SA, Hashim AM, Jose J, Lindequist U, Nawwar MA . (). Phenolics from Brahea Aramata Fruits. In International congress and 53rd annual meeting of the society for medical plant research, Florence.
    • Jose J. (). Bacterial surface display library screening: a novel tool for drug discovery. In DPhG-Jahrestagung, Mainz.

    • Jose J, Otto GW, Meyer TF . (). The integration site of the iga gene in commensal Neisseria sp. . Molecular Genetics and Genomics, 269(2), 197–204. doi: 10.1007/s00438-002-0799-6.
    • Talker D, Jose J, Glieder A, Pressnig M, Stubenrauch G, Schwab H . (). Esterase EstE from Xanthomonas vesicatoria (Xv_EstE) is an outer membrane protein capable of hydrolyzing long chain polar esters. Applied Microbiology and Biotechnology, 61(5-6), 479–487. doi: 10.1007/s00253-003-1227-5.
    • Jose J, Handel S . (). Monitoring the cellular surface display of recombinant proteins by cysteine labeling and flow cytometry. . ChemBioChem, 4(5), 396–405. doi: 10.1002/cbic.200200530.
    • Heinzle E, Weiss S, Wolfbeis O, Arain S, Klimant I, John G, Räbiger T, Müller G, Waltenberger H, Schultheiss E, Jose J . (). Mikrotiterplatten-Reaktoren mit integrierten pH-Sensoren und Autodisplay in E. coli zur evolutiven Enzymentwicklung. Transkript, 9, 59–62.
    • Jose J, Betscheider D, Ray S, Lengauer T & Zangen D. (). New inhibitors of human cathepsin G identified by surface display library screening and peptide-protein docking. In Akin, Ahmet et al. (Eds.), Proceedings of 7th International Symposium on Pharmaceutical Sciences (ISOPS-7) (pp. 46–49). Ankara: Tasarim Basim.
    • Jose J, Betscheider D, Zangen D . (). New Inhibitors of Human Cathepsin G by Bacterial Surface Display Library Screening. Actual trends in computer-assisted drug development. In Frühjahrstagung der DPhG Fachgruppe Pharmazeutische/Medizinische Chemie, Düsseldorf.
    • Batzl-Hartmann C, Maas RM, Hurst L, Jose J . (). A taylor-made test system for early intestinal absorption assessment. In 7th International Symposium on Pharmaceutical Sciences, Ankara.
    • Jose J, Winterer E, Handel S . (). Synthesis of rare sugars by whole cells of E. coli using Autodisplay of Sorbit Dehydrogenase. In GDCH Fachgruppe Medizinische Chemie, Annual Meeting “Frontiers in Medicinal Chemistry”, Fulda.
    • Batzl-Hartmann C, Maas RM, Hurst L, Jose J . (). A taylor-made test system for early intestinal absorption assessment. In GDCH Fachgruppe Medizinische Chemie, Annual Meeting “Frontiers in Medicinal Chemistry”, Fulda.
    • Jose J, Handel S . (). “Cystope tagging”: a novel tool for the labeling of recombinant proteins with promising bioanalytic applications. In DPhG-Jahrestagung, Würzburg.
    • Betscheider D, Ray S, Lengauer T & Jose J. (). Structure-activity relationship of peptidic human cathepsin G inhibitors obtained by surface display library screening. In DPhG-Jahrestagung, Würzburg.
    • Winterer E, Handel S, Jose J . (). A whole cell biocatalyst for the synthesis of rare sugars obtained by Autodisplay of sorbit dehydrogenase in E. coli. In DPhG-Jahrestagung, Würzburg.

    • Jose J, Bernhardt R, Hannemann F . (). Cellular surface display of dimeric Adx and whole cell P450-mediated steroid synthesis on E. coli. Journal of Biotechnology, 95(3), 257–268. doi: 10.1016/S0168-1656(02)00030-5.
    • Schultheiss E, Paar C, Schwab H, Jose J . (). Functional esterase surface display by the autotransporter pathway in Escherichia coli. . Journal of Molecular Catalysis B: Enzymatic, 18(1-3), 89–97. doi: 10.1016/S1381-1177(02)00063-2.
    • Zangen D, Jose J . (). Cellular surface display of protease inhibitors: selection by enzyme binding and flow cytometry. In Fourth European Graduate Student Meeting, Frankfurt.
    • Schultheiss E, Weiss S, Heinzle E, Jose J . (). Functional surface display of esterase ApeE in Escherichia coli: a step towards the molecular evolution. In Fourth European Graduate Student Meeting, Frankfurt.
    • Schultheiss E, Weiss S, Heinzle E, Jose J . (). Surface display of active esterase ApeE by the autotransporter pathway in Escherichia coli. In Advanced course on biocatalysis, Delft.
    • Weiss S, Schultheiss E, Jose J, Klimant I, Heinzle E . (). Screening of Hydrolases Displayed on the Surface of E. coli Using 96 Well Microplates with Integrated pH-Sensor. In Biocat2002, International Congress on Biocatalysis, Hamburg.
    • Handel S, Jose J . (). Surface display of active sorbitol dehydrogenase in Escherichia coli. In Biocat2002, International Congress on Biocatalysis, Hamburg.
    • Schultheiss E, Weiss S, Heinzle E, Jose J . (). Surface Display of Functional Esterases in E. coli. In Biocat2002, International Congress on Biocatalysis, Hamburg.
    • Jose J, Zangen D . (). Selection of protease inhibitors by cellular surface display, enzyme labeling and flow cytometry. In Jahrestagung der DPhG, FU Berlin 2002, Berlin.
    • Jose J. (). Towards chiral synthesis and directed evolution: cellular surface display of enzymes and enzyme inhibitors. In Gemeinsame Jahrestagung der GDCH, Fachgruppe Medizinische Chemie, DPhG, Fachgruppe Pharmazeutische Chemie, Travemünde.
    • Betscheider D, Ray S, Zangen D, Schultheiss E, Lengauer T & Jose J. (). A new model for an inhibitor of human cathepsin G by bacterial surface display library screening and protein-peptide docking. In European Conference on Computational Biology 2002, Saarbrücken.
    • Hartmann RW, Ehmer PB, Haidar S, Jose J, Hector M, Klein CDP, Seidel S, Sergejew TF, Wachall BG, Wächter GA & Zhuang Y. (). Review: Inhibition of CYP17, a new strategy for the treatment of prostate cancer. Archiv der Pharmazie / Chemistry in Life Sciences, 2002(335), 1–10.

    • Jose J, Jähnig F, Meyer TF . (). Common structural features of IgA1-protease-like outer membrane protein autotransporters. Molecular Microbiology, 18(02), 378–380. doi: 10.1111/j.1365-2958.1995.mmi_18020378.x.

  • Supervised Doctoral Studies

    Lara Ute SzabóBuxus-Alkaloids as active compounds against pathogens causing tropical infectious diseases (Thesis written in German)
    Robin BirusUntersuchung zellulärer Effekte und pharmakokinetischer Eigenschaften von Inhibitoren der humanen Proteinkinase CK2
    Schulte, MartenUntersuchungen zum Einfluss posttranslationaler Modifikationen von humanem αS1-Casein auf dessen Struktur und zelluläre Funktion
    Mönninger, AlexanderEntwicklung und Synthese eines artifiziellen β-Glucosidase-Substrates zur kovalenten Markierung β-Glucosidase-positiver Bakterienzellen
    Neufeld, NellyNanopartikuläre DNA-Trägersysteme als alternative nicht-virale Gen-Vektoren
    Lengers, IsabelleUntersuchungen zur Oberflächenexpression der humanen Hyaluronidase Hyal1 und Identifizierung neuer Inhibitoren
    Stein, NoraProteinstabilisierung nanopartikulärer Arzneiformen
    Lenz, FlorianAutodisplay-basiertes Protein Engineering thermophiler Cellulasen und deren kombinierter Einsatz zur effizienten Konversion von Cellulose
    Eenink, Bernard Derk GertjanAncestral reconstruction and experimental test of long- and short term evolvability using the AP-superfamily as a model system
    Strätker, KatjaEntwicklung eines in vitro Testverfahrens für Inhibitoren der humanen Lipidkinase PIP5K1alpha und Identifikaion
    Bayer, MalteNeuropeptid-Reporter-Assay zur Bestimmung der Protease-Aktivität in komplexen Matrices
    Dilkaute, CarinaAutodisplay-basierte Bindungsstudien zur Wirkstoffentwicklung und Antikörperidentifizierung
    Meyers, AnnikaEntwicklung und Nutzung zelldichteabhängiger Promotoren zur autoinduzierten Genexpression in Pseudomonas putida
    Oerding, KatharinaKonstruktion von Ganzzellbiokatalysatoren und deren Einsatz in stark eutektischen Lösemitteln
    Nienberg, ChristianOrtsspezifische Fluoreszenzmarkierung der humanen Proteinkinase CK2-Untereinheiten und Untersuchung von Inhibitoren
    Tahan, TamaraUntersuchungen zur Phosphorylierung von rekombinantem humanem S1-Casein
    Gisbert Fenoy, CristinaAutodisplay of LRP1-IV and ApoE3 for the development of drug delivery systems across the blood-brain barrier
    Saenger, ThorstenUntersuchungen zur Struktur des humanen αS1-Casein und seiner Bindung an den Toll-like Rezeptor 4
    Schüürmann, Jan NiklasAutodisplay von Dehydrogenasen zur NADPH Regeneration an der Zelloberfläche
    Bollacke, AndreStruktur-Wirkungs-Beziehungen von CK2-Inhibitoren und Entwicklung eines Verfahrens zur Identifizierung von CK2-Isoform selektiven Substanzen
    Hollender, JoelExpression von CYP1A2, CYP2C9, CYP2C19 und CYP2D6 an der Oberfläche von Escherichia coli
    Quehl, PaulUntersuchungen zur Expression und Aktivität von humaner Cytochrom P450 Reduktase an der Zelloberfläche von Escherichia Coli
    Tozakidis, Iasson E.P.Autodisplay von Cellulasen auf Pseudomonas putida, Zymobacter palmae und Zymomonas mobilis - ein Ganzzell-Ansatz zur vereinfachten Hydrolyse von Cellulose
    Bopp, Bertan
    Gole, MarinaReproduzierbare vergleichende Fluoreszenzgelelektrophorese (CoFGE) bei singulärere Probenahme und ihre Anwendung auf den Nachweis atemwegsgängiger Proteinallergene in der Arbeitsmedizin
    Weckenbrock, WilhelmineAutodisplay eines vollständigen IgG-Antikörpers
    Orlando, ZoyaAutodisplay of hyaluronidases and inhibitor testing
    Look, JenniferNeuartige Liganden-modifizierte Nanopartikel als Trägersysteme für Nukleinsäuren
    Braukmann, AchimUntersuchung zu den physiologischen und pathophysiologischen Eigenschaften von humanem alphaS1 casein im Vergleich zu anderen Milchproteinen
    Tubeleviciute, AgneNovel steroid reductase from Escherichia coli: from identification and characterization towards the design of a whole-cell biocatalyst
    Altendorfer, IrinaExpression von αS1-Casein in humanen Endothelzellen und massenspektrometrische Quantifizierung von αS1-Casein in Muttermilch
    Goblirsch, MichaelAdhesive peptides
    Gawarzewski, IrisDetermination of the AIDA-I beta-barrel crystal structure: getting the clue to the autotransporter secretion pathway
    Thömmes, SarahEntwicklung und Autodisplay humaner Antikörperbibliotheken: neue Erythropoietin bindende Varianten
    Reicheneder, ClaudiaAutodisplay von Peptidbibliotheken und Screening nach adhäsiven Peptiden und Inhibitoren der humanen Proteinkinase CK2
    Stephanie SchumacherAutodisplay of functional P450 enzymes in Escherichia coli
    Kranen, EvaAutodisplay komplexer Enzyme für biokatalytische Anwendungen
    Detzel, ChristianAutodisplay von Nitrilasen zur Umsetzung von Nitrilen zu Carbonsäuren
    Petermann, KlaudiaAutodisplay von humanen Antigenen als Basis für die beschleunigte Entwicklung von ELISA
    Gratz, AndreasAutodisplay der humanen Proteinkinase CK2 und Entwicklung eines Verfahrens zur Inhibitionstestung
    Kaeßler, AndreAutodisplay humaner Hyaluronidasen und Entwicklung von Verfahren zur Testung von Inhibitoren
    Winterer, ElisaUntersuchungen zur Struktur und Funktion der Transportdomänen des Autodisplay Systems
    Betscheider, DirkAutodisplay von Peptidbibliotheken und Screening nach neuen Cathepsin G Inhibitoren mittels Durchflusszytometrie
    Blasshofer, FelixAutodisplay funktioneller Antikörperfragmente in Escherichia coli
    von Schwichow, SteffenEntwicklung eines Ganzzell-Biokatalysators durch Autodisplay von Sorbitol Dehydrogenase
    Schultheiss, EvaAutodisplay aktiver Esterasen und Konstruktion von Enzymbibliotheken
    Zangen, DirkAutodisplay von Enzyminhibitoren

  • Scientific Talk

    • Prof. Dr. Joachim Jose (): ‘METHODS TO MEASURE PROTEIN-PROTEIN INTERACTIONS AND DISCOVERY OF POTENT INHIBITORS’. 2nd International Symposium on Advances in Pharmaceutical Analysis (APA 2018, Lille, France, .