| Cufe J, Gierse F, Schäfers KP, Hermann S, Schäfers MA, Backhaus P, Büther F. Dispersion-corrected extracorporeal arterial input functions in PET studies of mice: a comparison to intracorporeal microprobe measurements. EJNMMI Res 2023;13: 86. Abstract
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| Galbiati A, Dorten P, Gilardoni E, Gierse F, Bocci M, Zana A, Mock J, Claesener M, Cufe J, Büther F, Schäfers K, Hermann S, Schäfers M, Neri D, Cazzamalli S, Backhaus P. Tumor-Targeted Interleukin 2 Boosts the Anticancer Activity of FAP-Directed Radioligand Therapeutics. J Nucl Med 2023Abstract
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| Backhaus P, Gierse F, Burg MC, Büther F, Asmus I, Dorten P, Cufe J, Roll W, Neri D, Cazzamalli S, Millul J, Mock J, Galbiati A, Zana A, Schäfers KP, Hermann S, Weckesser M, Tio J, Wagner S, Breyholz H-J, Schäfers M. Translational imaging of the fibroblast activation protein (FAP) using the new ligand [(68)Ga]Ga-OncoFAP-DOTAGA. Eur J Nucl Med Mol Imaging 2022;49: 1822-1832. Abstract
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| Follin M Chyzha R Sunga CH Breton D Maalmic J Chaminadea T Delagnes E Schaefers K Weinheimer C Yvon D Sharyy V. High resolution MCP-PMT Readout Using Transmission Lines. Nucl Instrum Method 2022Abstract
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| Gerke B Peters S Marquardt N Huhmann C Hannen V M Holtkamp M Karst U Yvon D Sharyy V Weinheimer C Schäfers K. Suppression of electrical breakdown phenomena in liquid TriMethyl Bismuth based ionization detectors. J Inst 2022Abstract
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| Peters S Gerke B Hannen V Huhmann C Marquardt N Schäfers K Yvon D Sharyy V Weinheimer C. Electro-purification studies and first measurement of relative permittivity of TMBi. J Inst 2022Abstract
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| Schelhaas S, Frohwein LJ, Wachsmuth L, Hermann S, Faber C, Schäfers KP, Jacobs AH. Voxel-Based Analysis of the Relation of 3'-Deoxy-3'-[(18)F]fluorothymidine ([(18)F]FLT) PET and Diffusion-Weighted (DW) MR Signals in Subcutaneous Tumor Xenografts Does Not Reveal a Direct Spatial Relation of These Two Parameters. Mol Imaging Biol 2022;24: 359-364. Abstract
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| Backhaus P, Büther F, Wachsmuth L, Frohwein L, Buchholz R, Karst U, Schäfers K, Hermann S, Schäfers M, Faber C. Toward precise arterial input functions derived from DCE-MRI through a novel extracorporeal circulation approach in mice. Magn Reson Med 2020;84: 1404-1415. Abstract
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| Farradèche M, Tauzin G, Mols J-P, Bard J-P, Dognon J-P, Weinheimer C, Schäfers KP, Sharyy V, Yvon D. Ionization parameters of Trimethylbismuth for high-energy photon detection. Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detector 2020;958: 162646. Abstract
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| Pösse S, Büther F, Mannweiler D, Hong I, Jones J, Schäfers M, Schäfers KP. Comparison of two elastic motion correction approaches for whole-body PET/CT: motion deblurring vs gate-to-gate motion correction. EJNMMI Phys 2020;7Abstract
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| Schmitzer B, Schäfers KP, Wirth B. Dynamic Cell Imaging in PET With Optimal Transport Regularization. IEEE Trans Med Imaging 2020;39: 1626-1635. Abstract
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| Vahle T, Bacher M, Rigie D, Fenchel M, Speier P, Bollenbeck J, Schafers KP, Kiefer B, Boada FE. Respiratory Motion Detection and Correction for MR Using the Pilot Tone: Applications for MR and Simultaneous PET/MR Examinations. Invest Radiol 2020;55: 153-159. Abstract
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| Bolwin K, Czekalla B, Frohwein LJ, Büther F, Schäfers KP. Anthropomorphic thorax phantom for cardio-respiratory motion simulation in tomographic imaging. Phys Med Biol 2018;63: 035009. Abstract
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| Büther F, Ernst I, Frohwein LJ, Pouw J, Schäfers KP, Stegger L. Data-driven gating in PET: Influence of respiratory signal noise on motion resolution. Med Phys 2018;45: 3205-3213. Abstract
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| Cal-Gonzalez J, Li X, Heber D, Rausch I, Moore SC, Schafers K, Hacker M, Beyer T. Partial volume correction for improved PET quantification in (18)F-NaF imaging of atherosclerotic plaques. J Nucl Cardiol 2018;25: 1742-1756. Abstract
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| Cal-González J, Tsoumpas C, Lassen ML, Rasul S, Koller L, Hacker M, Schäfers K, Beyer T. Impact of motion compensation and partial volume correction for[super:18]F-NaF PET/CT imaging of coronary plaque. Phys. Med. Biol. 2018;63: 015005. Abstract
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| Frohwein LJ, Hess M, Schlicher D, Bolwin K, Büther F, Jiang X, Schäfers KP. PET attenuation correction for flexible MRI surface coils in hybrid PET/MRI using a 3D depth camera. Phys Med Biol 2018;63: 025033. Abstract
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| Schelhaas S, Wachsmuth L, Hermann S, Rieder N, Heller A, Heinzmann K, Honess DJ, Smith D-M, Fricke IB, Just N, Doblas S, Sinkus R, Döring C, Schäfers KP, Griffiths JR, Faber C, Schneider R, Aboagye EO, Jacobs AH. Thymidine Metabolism as a Confounding Factor for 3'-Deoxy-3'-(18)F-Fluorothymidine Uptake After Therapy in a Colorectal Cancer Model. J Nucl Med 2018;59: 1063-1069. Abstract
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| Zumhagen S, Vrachimis A, Stegger L, Kies P, Wenning C, Ernsting M, Muller J, Seebohm G, Paul M, Schafers K, Stallmeyer B, Schafers M, Schulze-Bahr E. Impact of presynaptic sympathetic imbalance in long-QT syndrome by positron emission tomography. Heart 2018;104: 332-339. Abstract
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| Bolwin K, Vernekohl D, Lühder J, Czekalla B, Wessels JP, Schäfers KP. Development of a clear sub-millimeter small animal PET scanner by reducing the influence of the non-collinearity effect. J. Inst. 2017;12: C03006-C03006. Abstract
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| Cal-Gonzalez J, Li X, Heber D, Rausch I, Moore SC, Schafers K, Hacker M, Beyer T. Partial volume correction for improved PET quantification in 18F-NaF imaging of atherosclerotic plaques. J Nucl Cardiol 2017: 1–15. Abstract
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| Heß M, Büther F, Schäfers KP. Data-Driven Methods for the Determination of Anterior-Posterior Motion in PET. IEEE Trans Med Imaging 2017;36: 422-432. Abstract
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| Büther F, Vehren T, Schäfers KP, Schäfers M. Impact of Data-driven Respiratory Gating in Clinical PET. Radiology 2016;281: 229-238. Abstract
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| Fricke IB, Viel T, Worlitzer MM, Collmann FM, Vrachimis A, Faust A, Wachsmuth L, Faber C, Dolle F, Kuhlmann MT, Schafers K, Hermann S, Schwamborn JC, Jacobs AH. 6-hydroxydopamine-induced Parkinson's disease-like degeneration generates acute microgliosis and astrogliosis in the nigrostriatal system but no bioluminescence imaging-detectable alteration in adult neurogenesis. Eur J Neurosci 2016;43: 1352-1365. Abstract
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| Hermann S, Kuhlmann MT, Starsichova A, Eligehausen S, Schafers K, Stypmann J, Tiemann K, Levkau B, Schafers M. Imaging Reveals the Connection Between Spontaneous Coronary Plaque Ruptures, Atherothrombosis, and Myocardial Infarctions in HypoE/SRBI-/- Mice. J Nucl Med 2016;57: 1420-1427. Abstract
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| Range FT, Kies P, Schafers KP, Breithardt G, Schober O, Wichter T, Schafers MA. Sex differences in absolute myocardial perfusion Non-invasive H2(15)O-PET in young healthy adults. Nuklearmedizin 2016;55: 196-202. Abstract
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| Reinartz G, Haverkamp U, Wullenkord R, Lehrich P, Kriz J, Büther F, Schäfers K, Schäfers M, Eich HT. 4D-Listmode-PET-CT and 4D-CT for optimizing PTV margins in gastric lymphoma : Determination of intra- and interfractional gastric motion. Strahlenther Onkol 2016;192: 322-332. Abstract
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| Ersepke T, Büther F, Heß M, Schäfers KP. A contactless approach for respiratory gating in PET using continuous-wave radar. Med Phys 2015;42: 4911. Abstract
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| Frohwein LJ, Hoerr V, Faber C, Schäfers KP. Correction of MRI-induced geometric distortions in whole-body small animal PET-MRI. Med. Phys. 2015;42: 3848-3858. Abstract
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| Heß M, Büther F, Gigengack F, Dawood M, Schäfers KP. A dual-Kinect approach to determine torso surface motion for respiratory motion correction in PET. Med. Phys. 2015;42: 2276-2286. Abstract
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| Reilmann R, Lippross V, Holzner E, Gigengack F, Bohlen S, Kugel H, Deppe M, Osada N, Lucke M, Riess O, Nguyen HP, Von Horsten S, Schafers K, Schafers M, Jacobs AH, Hermann S. FDG muPET Fails to Detect a Disease-Specific Phenotype in Rats Transgenic for Huntington's Disease - A 15 Months Follow-up Study. J Huntingtons Dis 2015;4: 37-47. Abstract
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| Schmid S, Jiang X, Schafers K. Puzzle Approach to Pose Tracking of a Rigid Object in a Multi Camera System. Lect Notes Comput Sc 2015;9256: 337-349. Abstract
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| Fieseler M, Gigengack F, Jiang X, Schafers KP. Motion correction of whole-body PET data with a joint PET-MRI registration functional. Biomed Eng Online 2014;13 Suppl 1: S2. Abstract
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| Kesner AL, Schleyer PJ, Büther F, Walter MA, Schäfers KP, Koo PJ. On transcending the impasse of respiratory motion correction applications in routine clinical imaging - a consideration of a fully automated data driven motion control framework. EJNMMI Phys 2014;1: 8. Abstract
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| Lamare F, Le Maitre A, Dawood M, Schafers KP, Fernandez P, Rimoldi OE, Visvikis D. Evaluation of respiratory and cardiac motion correction schemes in dual gated PET/CT cardiac imaging. Med Phys 2014;41: 072504. Abstract
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| Schäfers KP, Bolwin K, Büther F, Hermann S, Jacobs AH, Kösters T, Kuhlmann M, Schäfers M, Viel T. High-Resolution Small Animal Imaging. In: Comprehensive Biomedical Physics 2014;Elsevier, Oxford: 181-211. Abstract
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| Büther F, Ernst I, Hamill J, Eich HT, Schober O, Schäfers M, Schäfers KP. External radioactive markers for PET data-driven respiratory gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2013;40: 602-614. Abstract
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| Dawood M, Gigengack F, Jiang X, Schäfers KP. A mass conservation-based optical flow method for cardiac motion correction in 3D-PET. Med Phys 2013;40: 012505. Abstract
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| Fieseler M, Kugel H, Gigengack F, Kösters T, Büther F, Quick HH, Faber C, Jiang X, Schäfers KP. A dynamic thorax phantom for the assessment of cardiac and respiratory motion correction in PET/MRI: A preliminary evaluation. Nucl Instrum Methods Phys Res A 2013;702: 59-63. Abstract
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| Gigengack F, Ruthotto L, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Whole-Body PET-CT Segmentation using a Passive Contour Distance. Lect Notes Comput Sc 2013;7766: 82-92. Abstract
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| Gottschlag H, Kösters T, Vernekohl D, Reygers K, Schäfers KP, Wübbeling F, Wessels JP. Towards Quantitative Image Reconstruction Using Monte-Carlo Simulations in Multi-Wire Proportional Chamber-Based Small Animal PET. IEEE Trans Nucl Sci 2013;60: 3343-3354. Abstract
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| Jiang X, Dawood M, Gigengack F, Risse B, Schmid S, Tenbrinck D, Schäfers K. Biomedical imaging: A computer vision perspective. Lect Notes Comput Sc 2013;8047: 1-19. Abstract
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| Schmid S, Jiang X, Schäfers K. High-precision lens distortion correction using smoothed thin plate splines. Lect Notes Comput Sc 2013;8048: 432-439. Abstract
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| Tenbrinck D, Schmid S, Jiang X, Schäfers K, Stypmann J. Histogram-based Optical Flow for Motion Estimation in Ultrasound Imaging. J Math Imaging Vision 2013;47(1): 138-150.
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| Waerzeggers Y, Viel T, Schäfers S, Wagner S, Faust A, Riemann B, Kopka K, Schober O, Schäfers K, Jacobs AH. Positron Emission Tomography (PET)-based Molecular Imaging. Part 5 - Imaging Technologies in Animal Tumor Models: Measuring Brain Tumor Growth and Metabolism 2013;Neuromethods; 77: 301-327.
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| Gigengack F, Ruthotto L, Burger M, Wolters C, Jiang X, Schäfers K. Motion Correction in Dual Gated Cardiac PET using Mass-Preserving Image Registration. IEEE Trans Med Imaging 2012;31: 698-712. Abstract
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| Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Hermann S, Schäfers KP. Atlas-Based Segmentation Using Passive Contours. IEEE NSS/MIC 2012: 3015-3016.
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| Gigengack F, Ruthotto L, Kösters T, Jiang X, Modersitzki J, Burger M, Wolters CH, Schäfers KP. Pipeline for Motion Correction in Dual Gated PET. IEEE NSS/MIC 2012: 2983-2984. Abstract
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| Paul M, Rahbar K, Gerss J, Kies P, Schober O, Schäfers K, Breithardt G, Schulze-Bahr E, Wichter T, Schäfers M. Microvascular dysfunction in nonfailing arrhythmogenic right ventricular cardiomyopathy. Eur J Nucl Med Mol Imaging 2012;39: 416-420. Abstract
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| Ruthotto L, Gigengack F, Burger M, Wolters CH, Jiang X, Schäfers KP, Modersitzki J. A Simplified Pipeline for Motion Correction in Dual Gated Cardiac PET. In: Bildverarbeitung für die Medizin 2012: 51-56. Abstract
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| Engbers R, Benning M, Heins P, Schäfers K, Burger M. Sparse recovery in myocardial blood flow quantification via PET. IEEE NSS/MIC 2011: 3742-3744.
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| Fieseler M, Kosters T, Gigengack F, Braun H, Quick HH, Schäfers KP, Jiang X. Motion correction in PET-MRI: A human torso phantom study. IEEE NSS/MIC 2011: 3586-3588.
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| Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of PET: Displacement field vs spline transformation. IEEE NSS/MIC 2011: 3088-3090.
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| Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers KP. Mass-preserving motion correction of dual gated cardiac PET. IEEE NSS/MIC 2011: 3206-3208.
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| Kösters T, Schäfers KP, Wübbeling F. EMRECON: An expectation maximization based image reconstruction framework for emission tomography data. IEEE NSS/MIC 2011: 4365-4368.
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| Muller J, Brune C, Sawatzky A, Kosters T, Schäfers KP, Burger M. Reconstruction of short time PET scans using Bregman iterations. IEEE NSS/MIC 2011: 2383-2385.
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| Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel medical image reconstruction: from graphics processing units (GPU) to grids. J Supercomp 2011;52: 151-160. Abstract
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| Schmid S, Tenbrinck D, Jiang X, Schäfers K, Tiemann K, Stypmann J. Histogram-Based Optical Flow for Functional Imaging in Echocardiography. Lect Notes Comput Sc 2011;6854/2011: 477-485. Abstract
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| Seidler DG, Mohamed NA, Bocian C, Stadtmann A, Hermann S, Schäfers K, Schäfers M, Iozzo RV, Zarbock A, Götte M. The role for decorin in delayed-type hypersensitivity. J Immunol 2011;187: 6108-6119. Abstract
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| Buscher K, Judenhofer MS, Kuhlmann MT, Hermann S, Wehrl HF, Schäfers KP, Schäfers M, Pichler BJ, Stegger L. Isochronous assessment of cardiac metabolism and function in mice using hybrid PET/MRI. J Nucl Med 2010;51: 1277-1284. Abstract
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| Büther F, Ernst I, Dawood M, Kraxner P, Schäfers M, Schober O, Schäfers KP. Detection of respiratory tumour motion using intrinsic list mode-driven gating in positron emission tomography. Eur J Nucl Med Mol Imaging 2010;37: 2315-2327. Abstract
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| Dawood M, Brune C, Büther F, Jiang X, Burger M, Schober O, Schäfers M, Schäfers KP. A continuity equation based optical flow method for cardiac motion correction in 3 D PET data. Lect Notes Comput Sc 2010;6326: 88-97. Abstract
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| Ernst L, Büther F, Dawood M, Moustakis C, Willich N, Schäfers K, Boelling T. Listmode based PET/CT planning for motion detection in high precision radiotherapy. Strahlenther Onkol 2010;186: 13-14.
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| Gigengack F, Ruthotto L, Burger M, Wolters CH, Jiang X, Schäfers K. Motion correction of cardiac PET using mass-preserving registration. IEEE NSS/MIC 2010: 3317-3319.
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| Law MP, Schäfers K, Kopka K, Wagner S, Schober O, Schäfers M. Molecular imaging of cardiac sympathetic innervation by 11C-mHED and PET: from man to mouse?. J Nucl Med 2010;51: 1269-1276. Abstract
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| Schnöckel U, Hermann S, Stegger L, Law M, Kuhlmann M, Schober O, Schäfers K, Schäfers M. Small-animal PET: a promising, non-invasive tool in pre-clinical research. Eur J Pharm Biopharm 2010;74: 50-54. Abstract
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| Tenbrinck D, Dawood M, Gigengack F, Fieseler M, Jiang X, Schäfers K. Motion correction in Positron Emission Tomography considering Partial Volume Effects in optical flow estimation. IEEE ISBI 2010: 1233-1236. Abstract
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| Büther F, Dawood M, Stegger L, Wübbeling F, Schäfers M, Schober O, Schäfers KP. List mode-driven cardiac and respiratory gating in PET. J Nucl Med 2009;50: 674-681. Abstract
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| Dawood M, Büther F, Schober O, Schäfers M, Schäfers KP. Wieviele respiratorische Gates? Einfluss der Anzahl an Gates auf atemgetriggerte PET Aufnahmen. Nuklearmedizin 2009;48: A23.
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| Dawood M, Büther F, Stegger L, Jiang X, Schober O, Schäfers M, Schäfers KP. Optimal number of respiratory gates in positron emission tomography: a cardiac patient study. Med Phys 2009;36: 1775-1784. Abstract
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| Ernst I, Büther F, Dawood M, Kraxner P, Moustakis C, Bolling T, Schober O, Schäfers K, Willich N. PET/CT for movement detection in high precision radiotherapy. Strahlenther Onkol 2009;185: 35-36.
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| Range FT, Paul M, Schäfers KP, Acil T, Kies P, Hermann S, Schober O, Breithardt G, Wichter T, Schäfers MA. Myocardial perfusion in nonischemic dilated cardiomyopathy with and without atrial fibrillation. J Nucl Med 2009;50: 390-396. Abstract
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| Schellmann M, Gorlatch S, Meiländer D, Kösters T, Schäfers K, Wübbeling F, Burger M. Parallel Medical Image Reconstruction: From Graphics Processors to Grids. Lect Notes Comput Sc 2009;5698: 457-473. Abstract
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| Stegger L, Heijman E, Schäfers KP, Nicolay K, Schäfers MA, Strijkers GJ. Quantification of left ventricular volumes and ejection fraction in mice using PET, compared with MRI. J Nucl Med 2009;50: 132-138. Abstract
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| Benning M, Kösters M, Wübbeling F, Schäfers K, Burger M. A nonlinear variational method for improved quantification of myocardial blood flow using dynamic H215O pET. IEEE NSS 2008: 4472-4477.
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| Dawood M, Büther F, Jiang X, Schäfers KP. Respiratory motion correction in 3-D PET data with advanced optical flow algorithms. IEEE Trans.Med.Imaging 2008;27: 1164-1175. Abstract
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| Dawood M, Kösters T, Fieseler M, Büther F, Jiang X, Schäfers KP. Motion Correction on Dual ECG and Respiratory Gated 0440 3D Cardiac PET/CT Data. lncs 2008: 155-162.
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| Riemann B, Schäfers KP, Schober O, Schäfers M. Small animal PET in preclinical studies: opportunities and challenges. Q J Nucl Med Mol Imaging 2008;52: 215-221.
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| Schafers KP, Stegger L. Combined imaging of molecular function and morphology with PET/CT and SPECT/CT: image fusion and motion correction. Basic Res Cardiol 2008;103: 191-199. Abstract
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| Schnöckel U, Reuter S, Stegger L, Schlatter E, Schäfers KP, Hermann S, Schober O, Gabriels G, Schäfers M. Dynamic 18F-fluoride small animal PET to noninvasively assess renal function in rats. Eur J Nucl Med Mol Imaging 2008;35: 2267-2274. Abstract
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| Büther F, Stegger L, Dawood M, Range F, Schäfers M, Fischbach R, Wichter T, Schober O, Schäfers KP. Effective methods to correct contrast agent-induced errors in PET quantification in cardiac PET/CT. J Nucl Med 2007;48: 1060-1068. Abstract
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| Dawood M, Büther F, Lang N, Schober O, Schäfers KP. Respiratory gating in positron emission tomography: a quantitative comparison of different gating schemes. Med Phys 2007;34: 3067-3076. Abstract
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| Dawood M, Fieseler M, Büther F, Jiang X, Schäfers KP. A Multi-resolution Optical Flow Based Approach to Respiratory Motion Correction in 3D PET/CT Images. Lect Notes Comput Sc 2007: 314-322. Abstract
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| Lang N, Hermann S, Hold S, Mienkina M, Stegger L, Stypmann J, Schober O, Schäfers M, Schäfers KP, Schmitz G. Hybrid 3D Sono/PET in a mouse. Eur J Nucl Med Mol Imaging 2007;34: 1706-1707. Abstract
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| Range FT, Schäfers M, Acil T, Schäfers KP, Kies P, Paul M, Hermann S, Brisse B, Breithardt G, Schober O, Wichter T. Impaired myocardial perfusion and perfusion reserve associated with increased coronary resistance in persistent idiopathic atrial fibrillation. Eur Heart J 2007;28: 2223-2230. Abstract
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| Stegger L, Schäfers K, Kopka K, Wagner S, Hermann S, Kies P, Law M, Schober O, Schäfers M. Molecular cardiovascular imaging using scintigraphic methods. Eur Radiol 2007;17: 1422-1432. Abstract
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| Dawood M, Büther F, Lang N, Jiang X, Schäfers KP. Transforming Static CT in Gated PET/CT Studies to Multiple Respiratory Phases. ICPR 2006: 1026-1029. Abstract
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| Dawood M, Lang N, Jiang X, Schäfers KP. Lung motion correction on respiratory gated 3-D PET/CT images. IEEE Trans Med Imaging 2006;25: 476-485. Abstract
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| Schäfers KP, Lang N, Stegger L, Schober O, Schäfers M. Gated listmode acquisition with the quadHIDAC animal PET to image mouse hearts. Z Med Phys 2006;16: 60-66. Abstract
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| Stegger L, Hoffmeier A-N, Schäfers KP, Hermann S, Schober O, Schäfers MA, Theilmeier G. Accurate noninvasive measurement of infarct size in mice with high-resolution PET. J Nucl Med 2006;47: 1837-1844. Abstract
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| Kies P, Wichter T, Schäfers M, Paul M, Schäfers KP, Eckardt L, Stegger L, Schulze-Bahr E, Rimoldi O, Breithardt G, Schober O, Camici PG. Abnormal myocardial presynaptic norepinephrine recycling in patients with Brugada syndrome. Circulation 2004;110: 3017-3022. Abstract
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| Schäfers M, Riemann B, Kopka K, Breyholz HJ, Wagner S, Schäfers KP, Law MP, Schober O, Levkau B. Scintigraphic imaging of matrix metalloproteinase activity in the arterial wall in vivo. Circulation 2004;109: 2554-2559. Abstract
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