Prof. Dr. Bart Jan Ravoo
Self-assembling biofunctional nanoparticles
Chemistry
Imaging Technology
Nanoparticles are promising carriers for intracellular delivery and contrast agents for molecular imaging. The key challenge for biomedical application of nanoparticles is their functionalization with suitable targeting units that direct the nanoparticles to a tissue of interest. In this project we will investigate new approaches to prepare tailor-made biofunctional nanoparticles using molecular self-assembly.
Vita
- 1988 - 1994: Studies in Chemistry, Groningen (NL)
- 1994 - 1998: PhD in Chemistry, Groningen (NL)
- 1999: Postdoctoral Fellow, University College Dublin (IRL)
- 2000 - 2002: Newman Scholar, University College Dublin (IRL)
- 2002 - 2006: Assistant Professor, University of Twente (NL)
- Since 2007: Professor, University of Münster, Germany
Selected references
Pottanam Chali S, Ravoo BJ. Polymer Nanocontainers for Intracellular Delivery. Angewandte Chemie International Edition. 2020; 59: 2962-2972. doi: 10.1002/anie.201907484.
De Vries WC, Kudruk S, Grill D, Niehues M, Matos ALL, Wissing M, Studer A, Gerke V, Ravoo BJ. Controlled Cellular Delivery of Amphiphilic Cargo by Redox-Responsive Nanocontainers. Advanced Science. 2019; 6: 1901935. doi: 10.1002/advs.201901935.
Schibilla F, Holthenrich A, Song B, Linard Matos A, Grill D, Rota Martir D, Gerke V, Zysman-Colman E, Ravoo BJ. Phosphorescent cationic iridium(III) complexes dynamically bound to cyclodextrin vesicles: applications in live cell imaging. Chemical Science. 2018; 9(40): 7822-7828. doi: 10.1039/C8SC02875C.
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