Refinement of animal experiments and housing conditions
Reproducibility and generalizability of animal experiments
Animal welfare
Cognition and emotion
Animal welfare and animal personality
CV
Academic Education
PhD-studies, Animal Welfare and Ethology, Justus-Liebig-Universität Gießen
Studies of Biology, Westfälische Wilhelms-Universität Münster
Positions
Professor for Behavioural Biology and Animal Welfare
Postdoctoral researcher, Department of Behavioural Biology, Westfälische Wilhelms-Universität Münster
Postdoctoral researcher, Animal Models in Psychiatry, Central Institute of Mental Health and Bernstein Center for Computational Neuroscience (BCCN), Mannheim / Heidelberg
Postdoctoral researcher, Animal Welfare and Ethology, Veterinary Medicine, Justus-Liebig-Universität Gießen
PhD student, Animal Welfare and Ethology, Veterinary Medicine, Justus-Liebig-Universität Gießen
Honors
Margarete von Wrangell-Habilitationsprogramm – Ministerium für Wissenschaft, Forschung und Kunst Baden-Württemberg
Member of the Coordination Commission for Animal Experimentation, University of Münster
Member of the Hessian Animal Welfare Committee
Member of the Human Affectome Project, Neuroqualia, Happiness Team, Nova Scotia, Canada
Member of the Young North Rhine-Westphalian Academy of Sciences, Humanities and the Arts (“Junges Kolleg” NRW)
Member of the Ethological Society e.V.
Member of International Society of Applied Ethology (ISAE)
Appointments
Ruf auf eine Professur für "In vitro und in vivo Modelle" (§ 98 UG 2002), Veterinärmedizinische Universität Wien University of Veterinary Medicine Vienna, In vitro und in vivo Modelle – rejected
Ruf auf eine Professur für Verhaltensbiologie und Tierschutz (W2), Westfälische Wilhelms-Universität Münster University of Münster, Verhaltensbiologie und Tierschutz (W2) – accepted
Call for a temporary W2-S-professorship for “Animal welfare and refinement in animal experimentation”, Freie Universität Berlin and German Federal Institute for Risk Assessment (BfR) Freie Universität Berlin, Animal welfare and refinement in animal experimentation – rejected
Call for a W1-professorship for “Ethology of Farm Animals”, Landwirtschaftliche Fakultät, Rheinische-Friedrich-Wilhelms Universität Bonn University of Bonn, Ethology of Farm Animals (W1) – rejected
Projects
InChangE – Individualisierung in sich ändernden Umwelten ( – ) participations in other joint project: MKW - Förderlinie "Profilbildung" | Project Number: PROFILNRW-2020-143-B
RTG 2220 EvoPAD – RTG 2220: Evolutionary Processes in Adaptation and Disease ( – ) Main DFG-Project Hosted at the University of Münster: DFG - Research Training Group | Project Number: GRK 2220/1
CRC TRR 212 A02 - Optimistic and pessimistic decision making under ambiguity: causes and consequences for niche choice and niche conformance ( – ) Subproject in DFG-Joint Project Hosted outside the University of Münster: DFG - Collaborative Research Centre | Project Number: TRR 212/1
Weidebilder - Kunst in der Ambivalenz der Mensch-Tier-Beziehung ( – ) Individual Granted Project: Bezirksregierung Münster | Project Number: 48.07.16-15/20 RKP
3T: Animal Protection, Animal Welfare, Animal Ethics ( – ) Internally at the University of Münster Funded Project: Uni Münster-internal funding - Topical Programs
The Individual in the Focus of Life Sciences ( – ) Internally at the University of Münster Funded Project: Uni Münster-internal funding - Topical Programs
CRC TRR 58 - A01: Life history, serotonin transporter genotype and anxiety-like behaviour: testing the "coping-with-challenge hypothesis" ( – ) Subproject in DFG-Joint Project Hosted at the University of Münster: DFG - Collaborative Research Centre | Project Number: TRR 58/4
Standardisierung, Heterogenisierung und Reproduzierbarkeit von Ergebnissen aus Tierversuchen ( – ) Individual Granted Project: DFG - Individual Grants Programme | Project Number: RI 2488/3-1
Publications
Bračić, M, Bierbaum, L, Peng, M, Nimalavachchlan, L, Siewert, V, Kaiser, S, Sachser, N, and Richter, SH. . “The behavioural ecology of optimism: judgement bias and foraging under predation risk in mice.” Animal Behaviour, № 219 122991. doi: 10.1016/j.anbehav.2024.10.005.
Rystrom, TL, Wesseler, Y, Richter, SH, Sachser, N, and Kaiser, S. . “Shaped by you: The effect of social partner on cortisol and behavior during adolescence in a female rodent.” Ethology, № 130 e13414. doi: 10.1111/eth.13414.
von Kortzfleisch, VT, and Richter, SH. . “Systematic heterogenization revisited: Increasing variation in animal experiments to improve reproducibility?” Journal of Neuroscience Methods, № 401 109992. doi: 10.1016/j.jneumeth.2023.109992.
Kaiser, M, Gadau, J, Kaiser, S, Müller, C, and Richter, SH. . “Individualized social niches in animals: Theoretical clarifications and processes of niche change.” BioScience, № 74: 146–158. doi: 10.1093/biosci/biad122.
Schiller D, Yu ANC, Alia-Klein N, ..., Richter SH, ... Lowe L. . “The human affectome.” Neuroscience and Biobehavioral Reviews, № 158 105450. doi: 10.1016/j.neubiorev.2023.105450.
Rystrom, TL, Richter, SH, Sachser, N, and Kaiser, S. . “Social niche shapes social behavior and cortisol concentrations during adolescence in female guinea pigs.” Hormones and Behavior, № 162 (105539) doi: 10.1016/j.yhbeh.2024.105539.
Kaiser, M.I., Killin, A., Abendroth, A.-K., Back, M.D., Baune, B.T., Bilstein, N., Breitmoser, Y., Caspers, B.A., Gadau, J., Gossmann, T.I., Kaiser, S., Krüger, O., Kurtz, J.Lengersdorf, D., Malsch, A. K. F., Müller, C. Rauthmann, J.F., Reinhold, K., Richter, S.H., Stummer, C., Trappes, R., Voelcker-Rehage, C., and Wittmann, M.J. . “Individualisation and individualised science across disciplinary perspectives.” European Journal for Philosophy of Science, № 14 (41) 41. doi: 10.1007/s13194-024-00602-8.
Sroka, MGU, Ambree, O, Dohmen, C, Palme, R, Kaiser, S, and Richter, SH. . “Personality matters – The interplay between consistent individual differences and mouse welfare in female C57BL6/J mice.” Frontiers in Animal Science, № 5 (14238) doi: 10.3389/fanim.2024.1423814.
Göbel, M., Kaiser, S., Richter, S.H., Wagner, P., and Wehrenberg, G. . “Specifically Unspecific – Simple Devices as Feasible and Effective Enrichment for Small Mammals.” Animal Behavior and Cognition, № 11 (3): 305–329. doi: 10.26451/abc.11.03.05.2024.
SH, Richter. . “Challenging current scientific practice: How a shift in research methodology could reduce animal use.” Lab Animal, № 53: 9–12. doi: 10.1038/s41684-023-01308-9.
Stieger, B, Wesseler, Y, Kaiser, S, Sachser, N, and Richter, SH. . “Behavioral lateralization of mice varying in serotonin transporter genotype.” Frontiers in Behavioral Neuroscience, № 16 1095567. doi: 10.3389/fnbeh.2022.1095567.
Kaiser, S, Korte, A, Wistuba, J, Baldy, M, Wissmann, A, Dubičanac, A, Richter, SH, and Sachser, N. . “Effects of castration and sterilization on cortisol responsiveness – a case study in male guinea pigs.” Frontiers in Veterinary Science, № 9 (1093157) doi: 10.3389/fvets.2022.1093157.
Segelcke, D, Linneman, J, Pradier, B, Kronenberg, D, Stange, R, Richter, SH, Görlich, D, Baldini, N, Di Pompo, G, Verri, WAJr., Avnet, S, and Pogatzki-Zahn, EM. . “Behavioral voluntary and social bioassays enabling identification of complex and sex-dependent pain-(-related) phenotypes in rats with bone cancer.” Cancers, № 15 (1565) doi: 10.3390/cancers15051565.
Quante, SM, Siewert, V, Palme, R, Kaiser, S, Sachser, N, and SH, Richter. . “The power of a touch: Regular touchscreen training but not its termination affects hormones and behavior in mice.” Frontiers in Behavioral Neuroscience, № 17 doi: 10.3389/fnbeh.2023.1112780.
Waterkamp, C, von Kortzfleisch, VT, Neu, C, Kitanovski, S, Richter, SH, and Hoffmann, D. . “Increasing information gain in animal research by improving statistical model accuracy.” contribution to the International Workshop on Mathematical Modeling and Scientific Computing 2022, München doi: 10.1088/1742-6596/2514/1/012021.
Mutwill, AM, Schielzeth, H, Richter, SH, Kaiser, S, and Sachser, N. . “Conditional on the social environment? Roots of repeatability in hormone concentrations of male guinea pigs.” Hormones and Behavior, № 155 105423.
Bohn, L, Bierbaum, L, Kästner, N, von Kortzfleisch, VT, Kaiser, S, Sachser, N, and Richter, SH. . “Structural enrichment for laboratory mice: exploring the effects of novelty and complexity.” Frontiers in Veterinary Science, № 10 1207332. doi: 10.3389/fvets.2023.1207332.
Kaiser, S, and Richter, SH. . “Don’t worry, be happy? Ein verhaltensbiologischer Blick auf das Gefühlsleben der Tiere.” in Das unterschätzte Tier, edited by N Sachser, N Kästner and T Zimmermann. Reinbek: Rowohlt Taschenbuch Verlag.
Stieger, B, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “When left is right: The effects of paw preference training on behaviour in mice.” Behavioural Brain Research, № 430 (113929)
Von Kortzfleisch, VT, Ambrée, O, Karp, NA, Meyer, N, Novak, J, Palme, R, Rosso, M, Touma, C, Würbel, H, Kaiser, S, Sachser, N, and Richter, SH. . “Do multiple experimenters improve the reproducibility of animal studies?” PLoS Biology, № 20(3) (e3001564) doi: 10.1371/journal.pbio.3001564.
Rystrom, TL, Prawitt, RC, Richter, SH, Sachser, N, and Kaiser, S. . “Repeatability of endocrine traits and dominance rank in female guinea pigs.” Frontiers in Zoology, № 19 (1): 4. doi: 10.1186/s12983-021-00449-2.
Feige-Diller, J, Herrera-Rivero, M, Witten, A, Stoll, M, Kaiser, S, Richter, SH, and Sachser, N. . “The impact of varying food availability on gene expression in the liver: Testing the Match-Mismatch hypothesis.” Frontiers in Nutrition, № 9 (910762)
Bračić, M, Bohn, L, Siewert, V, von Kortzfleisch, V, Schielzeth, H, Kaiser, S, Sachser, N, and Richter, SH. . “Once an Optimist, Always an Optimist? Studying Cognitive Judgment Bias in Mice.” Behavioral Ecology, № 33: 775–788.
Herrera-Rivero, M, Bohn, L, Witten, A, Jüngling, K, Kaiser, S, Richter, SH, Stoll, M, and Sachser, N. . “Transcriptional profiles in the mouse amygdala after a cognitive judgment bias test largely depend on the genotype.” Frontiers in Molecular Neuroscience, № 15 1025389. doi: 10.3389/fnmol.2022.1025389.
Jaric, I, Voelkl, B, Clerc, M, Schmid, MW, Novak, J, Rosso, M, Rufener, R, von Kortzfleisch, VT, Richter, SH, Buettner, M, Bleich, A, Amrein, I, Wolfer, DP, Touma, C, Sunagawa, S, and Würbel, H. . “The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level.” PLoS Biology, № 20 (10) e3001837. doi: 10.1371/journal.pbio.3001837.
Siewert, V, and Richter, SH. . “Always Looking on the Bright Side of Life?” forschung. Das Magazin der Deutschen Forschungsgemeinschaft, № 3 (4): 24–27.
Jaric, I, Voelkl, B, Clerc, M, Schmid, MW, Novak, J, Rosso, M, Rufener, R, von Kortzfleisch, VT, Richter, SH, Buettner, M, Bleich, A, Amrein, I, Wolfer, DP, Touma, C, Sunagawa, S, and Würbel, H. . “The rearing environment persistently modulates mouse phenotypes from the molecular to the behavioural level.” PLoS Biology, № 20 (10) doi: 10.1371/journal.pbio.3001837 .
Feige-Diller, J, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “The impact of varying food availability on health and welfare in mice: Testing the Match-Mismatch hypothesis.” Physiology and Behavior, № 228 (113193) doi: 10.1016/j.physbeh.2020.113193.
Mutwill, AM, Schielzeth, H, Zimmermann, TD, Richter, SH, Kaiser, S, and Sachser, N. . “Individuality meets plasticity: Endocrine phenotypes across male dominance rank acquisition in guinea pigs living in a complex social environment.” Hormones and Behavior, № 131 104967. doi: 10.1016/j.yhbeh.2021.104967.
Desjardins, E, Kurtz, J, Kranke, N, Lindeza, A, and Richter, SH. . “Beyond standardization: Improving external validity and reproducibility in experimental evolution.” BioScience, № biab008 doi: 10.1093/biosci/biab008.
Stieger, B, Melotti, L, Quante, SM, Kaiser, S, Sachser, N, and Richter, SH. . “A step in the right direction: the effect of context, strain and sex on paw preference in mice.” Animal Behaviour, № 174: 21–30. doi: 10.1016/j.anbehav.2021.01.012.
Krakenberg, V, Wewer, M, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “Regular touchscreen training affects faecal corticosterone metabolites and anxiety-like behaviour in mice.” Behavioural Brain Research, № 401: 113080. doi: 10.1016/j.bbr.2020.113080.
Bodden, C, Wewer, M, Kästner, N, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “Not all mice are alike: Mixed-strain housing alters social behaviour.” Physiology and Behavior, № 228 (113220) doi: 10.1016/j.physbeh.2020.113220.
Alexander, R, Aragon, OR, Bookwala, J, Cherbuin, N, Gatt, JM, Kahrilas, IJ, Kästner, N, Lawrence, A, Lowe, L, Morrison, RG, Mueller, SC, Nusslock, R, Papadelis, C, Polnaszek, KL, Richter, SH, Silton, RL, and Styliadis, C. . “The neuroscience of positive emotions and affect: Implications for cultivating happiness and wellbeing.” Neuroscience and Biobehavioral Reviews, № 121: 220–249. doi: 10.1016/j.neubiorev.2020.12.002.
Melotti, L, Siestrup, S, Peng, M, Vitali, V, Dowling, D, von Kortzfleisch, VT, Bracic, M, Sachser, N, Kaiser, S, and Richter, SH. . “Individuality, as well as genetic background, affects syntactical features of courtship songs in male mice.” Animal Behaviour, № 180: 179–196.
SH, Richter. . “Reproduzierbarkeit von Verhaltensdaten (Kapitel 8.3).” in Methoden der Verhaltensbiologie, edited by M Naguib and ET Krause. Heidelberg: Springer Spektrum.
SH, Richter. . “Automated home-cage testing as a tool to improve reproducibility of behavioral research?” Frontiers in Neuroscience, № 14: 383.
Feige-Diller, J, Krakenberg, V, Bierbaum, L, Seifert, L, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “The effects of different feeding routines on welfare in laboratory mice.” Frontiers in Veterinary Science, № 6: 479.
Von Kortzfleisch, VT, Karp, NA, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “Improving reproducibility in animal research by splitting the study population into several ‘mini-experiments’.” Scientific Reports, № 10 (16579) doi: 10.1038/s41598-020-73503-4.
Krakenberg, V, Siestrup, S, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “Effects of different social experiences on emotional state in mice.” Scientific Reports, № 10 (15255) doi: 10.1038/s41598-020-71994-9.
Richter, SH, and von Kortzfleisch, V. . “It is time for an empirically informed paradigm shift in animal research.” Nature Reviews Neuroscience, № 21: 660. doi: 10.1038/s41583-020-0370-7.
Mutwill, AM, Zimmermann, TD, Hennicke, A, Richter, SH, Kaiser, S, and Sachser, N. . “Adaptive reshaping of the hormonal phenotype after social niche transition in adulthood.” Proceedings of the Royal Society B: Biological Sciences, № 287 20200667. doi: 10.1098/rspb.2020.0667.
Krakenberg, Viktoria, Siestrup, Sophie, Palme, Rupert, Kaiser, Sylvia, Sachser, Norbert, and Richter, SophieHelene. . “Effects of different social experiences on emotional state in mice.” Scientific Reports, № 10 (15255) doi: 10.1038/s41598-020-71994-9.
Mutwill, AM, Zimmermann, TD, Reuland, C, Fuchs, S, Kunert, J, Richter, SH, Kaiser, S, and Sachser, N. . “High reproductive success despite queuing – Socio-sexual development of males in a complex social environment.” Frontiers in Psychology, № 10 2810. doi: 10.3389/fpsyg.2019.02810.
Krakenberg, V, von Kortzfleisch, V, Kaiser, S, Sachser, N, and Richter, SH. . “Differential effects of serotonin transporter genotype on anxiety-like behavior and cognitive judgment bias in mice.” Frontiers in Behavioral Neuroscience, № 13: 263.
Haaker, J, Maren, S, Andreatta, M, Merz, CJ, Richter, J, Richter, SH, Drexler, Shira S, Lange, MD, Jüngling, K, Nees, F, Seidenbecher, T, Fullana, MA, Wotjak, C, and Lonsdorf, TB. . “Making translation work: Harmonizing cross-species methodology in the behavioural neuroscience of Pavlovian fear conditioning.” Neuroscience & Biobehavioral Reviews, № 107: 329–345.
Bodden, C, von Kortzfleisch, V, Karwinkel, F, Kaiser, S, Sachser, N, and Richter, SH. . “Heterogenising study samples across testing time improves reproducibility of behavioural data.” Scientific Reports, № 9: 8247.
Von Kortzfleisch, V, Kästner, N, Prange, L, Kaiser, S, Sachser, N, and Richter, SH. . “Have I been here before? Effects of repeated testing and age on the results of behavioural tests.” Behavioural Brain Research, № 367: 143–148.
Melotti, L, Kästner, N, Eick, AK, Schnelle, AL, Palme, R, Sachser, N, Kaiser, S, and Richter, SH. . “Can live with ‘em, can live without ‘em: pair housed male C57BL/6J mice show low aggression and increasing sociopositive interactions with age, but can adapt to single housing if separated.” Applied Animal Behaviour Science, № 214: 79–88.
Kästner, N, Richter, SH, Urbanik, S, Kunert, J, Waider, J, Lesch, K-P, Kaiser, S, and Sachser, N. . “Brain serotonin deficiency affects female aggression.” Scientific Reports, № 9 (1366)
Krakenberg, V, Woigk, I, Garcia, Rodriguez L, Kästner, N, Kaiser, S, Sachser, N, and Richter, SH. . “Technology or ecology? New tools to assess cognitive
judgement bias in mice.” Behavioural Brain Research, № 362: 279–287.
Richter, SH, and Hintze, S. . “From the individual to the population – and back again? Emphasising the role of the individual in animal welfare science.” Applied Animal Behaviour Science, № 212: 1–8.
Bodden, C, Siestrup, S, Palme, R, Kaiser, S, Sachser, N, and Richter, SH. . “Evidence-based severity assessment: Impact of repeated versus single open-field testing on welfare in C57BL/6J mice.” Behavioural Brain Research, № 336: 261–268.
Kästner, N, Richter, SH, Bodden, C, Palme, R, Kaiser, S, and Sachser, N. . “Varying social experiences in adulthood do not differentially affect anxiety-like behavior but stress hormone levels.” Frontiers in Behavioral Neuroscience, № 12: 72.
SH, Richter. . ““Never replicate a successful experiment” - Gedanken über Unschärfe im Tierversuch.” in Unschärfe – der Umgang mit fehlender Eindeutigkeit, edited by S Freitag, M Geierhos, R Asmani and JI Haug.
Kafkafi, N, Agassi, J, Chesler, EJ, Crabbe, JC, Crusio, WE, Eilam, D, Gerlai, R, Golani, I, Gomez-Marin, A, Heller, R, Iraqi, F, Jaljuli, I, Karp, NA, Morgan, H, Nicholson, G, Pfaff, DW, Richter, SH, Stark, PB, Stiedl, O, Stodden, V, Tarantino, LM, Tucci, V, Valdar, W, Williams, RW, Würbel, H, and Benjamini, Y. . “Reproducibility and replicability of rodent phenotyping in preclinical studies.” Neuroscience & Biobehavioral Reviews, № 87: 218–232.
SH, Richter. . “Aus dem VBIO.” Biologie in unserer Zeit (BIUZ), № 48: 23.
Sachser, N, Richter, SH, and Kaiser, S. . “Artgerecht/tiergerecht.” in Handbuch Tierethik, edited by JS Ach and D Borchers. Stuttgart: J.B. Metzler Verlag.
Richter, SH, Sachser, N, and Kaiser, S. . “Emotionen.” in Handbuch Tierethik, edited by JS Ach and D Borchers. Stuttgart: J.B. Metzler Verlag.
SH, Richter. . “Systematic heterogenization for better reproducibility in animal experimentation.” Lab Animal, № 46: 343–349. doi: 10.1038/laban.1330.
Meyer, N, Jenikejew, J, Richter, SH, Kaiser, S, and Sachser, N. . “Social experiences during adolescence affect anxiety-like behavior but not aggressiveness in male mice.” Behavioural Brain Research, № 326: 147–153. doi: 10.1016/j.bbr.2017.03.017.
Kästner, N, Richter, SH, Gamer, M, Kaiser, S, and Sachser, N. . “What a difference a day makes - female behaviour is less predictable near ovulation.” Royal Society Open Science, № 4 doi: 10.1098/rsos.160998.
Remmes, J, Bodden, C, Richter, SH, Lesting, J, Sachser, N, Pape, H-C, and Seidenbecher, T. . “Impact of life history on fear memory and extinction.” Frontiers in Behavioural Neuroscience, № 10: 185. doi: 10.3389/fnbeh.2016.00185.
Graulich, DM, Kaiser, S, Sachser, N, and Richter, SH. . “Looking on the bright side of bias – validation of an affective bias test for laboratory mice.” Applied Animal Behaviour Science, № 181: 173–181.
Richter, SH, Spinello, C, and Macrì, S. . “Improving external validity of experimental animal data.” in Animal Models for Human Cancer: Discovery and Development of Novel Therapeutics, edited by MI Martic-Kehl and PA Schubiger. Weinheim: Wiley-VCH Verlag.
Mallien, AS, Palme, R, Richetto, J, Muzzillo, C, Richter, SH, Vogt, MA, Inta, D, Riva, MA, Vollmayr, B, and Gass, P. . “Daily exposure to a touchscreen-paradigm and associated food restriction evokes an increase in adrenocortical and neural activity in mice.” Hormones and Behavior, № 81: 97–105.
Meyer, N, Richter, SH, Schreiber, RS, Kloke, V, Kaiser, S, Lesch, KP, and Sachser, N. . “The Unexpected Effects of Beneficial and Adverse Social Experiences during Adolescence on Anxiety and Aggression and Their Modulation by Genotype.” Frontiers in Behavioral Neuroscience, № 10 (97) doi: 10.3389/fnbeh.2016.00097.
Richter, SH, Kästner, N, Loddenkemper, DH, Kaiser, S, Sachser, and N. . “A time to wean? Impact of weaning age on anxiety-like behaviour and stability of behavioural traits in full adulthood.” PloS one, № 11(12): e0167652. doi: 10.1371/journal.pone.0167652.
Richter, SH, Kästner, N, Kriwet, M, Kaiser, S, and Sachser, N. . “Play matters - the surprising relationship between juvenile playfulness and anxiety in later life.” Animal Behaviour, № 114: 261–271. doi: 10.1016/j.anbehav.2016.02.003.
Sachser, N, and Richter, SH. . “Animals can tell us more.” Behavioral and Brain Sciences, № 38: 44–45.
Macri, S, and Richter, SH. . “The Snark was a Boojum – reloaded.” Frontiers in Zoology, № 12: S20.
Bodden, C, Richter, SH, Schreiber, RS, Kloke, V, Gerss, J, Palme, R, Lesch, K-P, Lewejohann, L, Kaiser, S, and Sachser, N. . “Benefits of adversity?! How life history affects the behavioral profile of mice varying in serotonin transporter genotype.” Frontiers in Behavioral Neuroscience, № 9: 47.
Kästner, N., Richter, S.H., Lesch, K.P., Schreiber, R.S., Kaiser, S., and Sachser, N. . “Benefits of a "vulnerability gene"? A study in serotonin transporter knockout mice.” Behavioural Brain Research, № 283 doi: 10.1016/j.bbr.2015.01.031.
Richter, SH, Vogel, AS, Ueltzhöffer, K, Muzzillo, C, Vogt, MA, Lankisch, K, Armbruster-Genç, DJ, Riva, MA, Fiebach, CJ, Gass, P, and Vollmayr, B. . “Touchscreen-paradigm for mice reveals cross-species evidence for an antagonistic relationship of cognitive flexibility and stability.” Frontiers in Behavioral Neuroscience, № 8: 154. doi: 10.3389/fnbeh.2014.00154.
Lima-Ojeda, JM, Vogt, MA, Richter, SH, Dormann, C, Schneider, M, Gass, P, and Inta, D. . “Lack of protracted behavioral abnormalities following intermittent or continuous chronic mild hypoxia in perinatal C57BL/6 mice.” Neuroscience Letters, № 577C: 77–82. doi: 10.1016/j.neulet.2014.06.022.
Richter, SH, Wollmann, E, Schmidt, M, Zillmann, U, Hellweg, R, Sprengel, R, and Gass, P. . “The effects of neonatal cryoanaesthesia-induced hypothermia on adult emotional behaviour and stress markers in C57BL/6 mice.” Behavioural Brain Research, № 270C: 300–306. doi: 10.1016/j.bbr.2014.05.002.
Richter, SH, Sartorius, A, Gass, P, and Vollmayr, B. . “A matter of timing: harm reduction in learned helplessness.” Behavioral and Brain Functions, № 10: 41.
Richter, SH, Gass, P, and Fuss, J. . “Resting Is Rusting: A Critical View on Rodent Wheel-Running Behavior.” Neuroscientist, № 20(4): 313–325. doi: 10.1177/1073858413516798.
Richter, SH, Zeuch, B, Lankisch, K, Gass, P, Durstewitz, D, and Vollmayr, B. . “Where have I been? Where should I go? Spatial working memory on a radial arm maze in a rat model of depression.” PloS one, № 8 (4): e62458. doi: 10.1371/journal.pone.0062458.
Hoyer, C, Richter, H, Brandwein, C, Riva, MA, and Gass, P. . “Preconceptional paternal exposure to a single traumatic event affects postnatal growth of female but not male offspring.” NeuroReport, № 24 (15): 856–60. doi: 10.1097/WNR.0000000000000007.
Richter, SH, Zeuch, B, Riva, MA, Gass, P, and Vollmayr, B. . “Environmental enrichment ameliorates depressive-like symptoms in young rats bred for learned helplessness.” Behavioural Brain Research, № 252: 287–92. doi: 10.1016/j.bbr.2013.06.021.
Würbel, H, Richter, SH, and Garner, JP. . “Reply to: "Reanalysis of Richter et al. (2010) on reproducibility".” Nature Methods, № 10 (5): 374. doi: 10.1038/nmeth.2446.
Fuss, J, Richter, SH, Steinle, J, Deubert, G, Hellweg, R, and Gass, P. . “Are you real? Visual simulation of social housing by mirror image stimulation in single housed mice.” Behavioural Brain Research, № 243: 191–8. doi: 10.1016/j.bbr.2013.01.015.
Pignatelli, M, Vollmayr, B, Richter, SH, Middei, S, Matrisciano, F, Molinaro, G, Nasca, C, Battaglia, G, Ammassari-Teule, M, Feligioni, M, Nisticò, R, Nicoletti, F, and Gass, P. . “Enhanced mGlu5-receptor dependent long-term depression at the Schaffer collateral-CA1 synapse of congenitally learned helpless rats.” Neuropharmacology, № 66: 339–47. doi: 10.1016/j.neuropharm.2012.05.046.
Richter, SH, Schick, A, Hoyer, C, Lankisch, K, Gass, P, and Vollmayr, B. . “A glass full of optimism: enrichment effects on cognitive bias in a rat model of depression.” Cognitive, Affective, and Behavioral Neuroscience, № 12 (3): 527–42. doi: 10.3758/s13415-012-0101-2.
Gross, AN, Richter, SH, Engel, AK, and Würbel, H. . “Cage-induced stereotypies, perseveration and the effects of environmental enrichment in laboratory mice.” Behavioural Brain Research, № 234 (1): 61–8. doi: 10.1016/j.bbr.2012.06.007.
Hoyer, C, Vogt, MA, Richter, SH, Zaun, G, Zahedi, Y, Maderwald, S, Ladd, ME, Winterhager, E, Grümmer, R, and Gass, P. . “Repetitive exposure to a 7 Tesla static magnetic field of mice in utero does not cause alterations in basal emotional and cognitive behavior in adulthood.” Reproductive Toxicology, № 34 (1): 86–92. doi: 10.1016/j.reprotox.2012.03.006.
Chourbaji, S, Hoyer, C, Richter, SH, Brandwein, C, Pfeiffer, N, Vogt, MA, Vollmayr, B, and Gass, P. . “Differences in mouse maternal care behavior - is there a genetic impact of the glucocorticoid receptor?” PloS one, № 6 (4): e19218. doi: 10.1371/journal.pone.0019218.
Richter, SH, Garner, JP, Zipser, B, Lewejohann, L, Sachser, N, Touma, C, Schindler, B, Chourbaji, S, Brandwein, C, Gass, P, van Stipdonk, N, van der, Harst J, Spruijt, B, Võikar, V, Wolfer, DP, and Würbel, H. . “Effect of population heterogenization on the reproducibility of mouse behavior: a multi-laboratory study.” PloS one, № 6 (1): e16461. doi: 10.1371/journal.pone.0016461.
SH, Richter. . “Illusion der perfekten Kontrolle.” Bild der Wissenschaft plus, № 2011: 20–23.
SH, Richter. . “Illusion der perfekten Kontrolle.” Vet Journal, № 12/11: 46–49.
Engel, AK, Gross, AN, Richter, SH, and Würbel, H. . “Variation in stress reactivity affects cage-induced stereotypies in female CD-1 (ICR) mice.” Applied Animal Behaviour Science, № 133: 101–108.
Gross, AN, Engel, AK, Richter, SH, Garner, JP, and Würbel, H. . “Cage-induced stereotypies in female ICR CD-1 mice do not correlate with recurrent perseveration.” Behavioural Brain Research, № 216 (2): 613–20. doi: 10.1016/j.bbr.2010.09.003.
Richter, SH, Garner, JP, Auer, C, Kunert, J, and Würbel, H. . “Systematic variation improves reproducibility of animal experiments.” Nature Methods, № 7 (3): 167–8. doi: 10.1038/nmeth0310-167.
SH, Richter. . “Standardization in animal experiments: Necessity or fallacy?” Dissertation thesis, Universität Münster.
Richter, SH, Garner, JP, and Würbel, H. . “Environmental standardization: cure or cause of poor reproducibility in animal experiments?” Nature Methods, № 6 (4): 257–61. doi: 10.1038/nmeth.1312.
Ambrée, O, Richter, H, Sachser, N, Lewejohann, L, Dere, E, de Souza, Silva MA, Herring, A, Keyvani, K, Paulus, W, and Schäbitz, WR. . “Levodopa Ameliorates Learning and Memory Deficits in a Murine Model of Alzheimer's Disease.” Neurobiology of Aging, № 30 (8): 1192–1204. doi: 10.1016/j.neurobiolaging.2007.11.010.
Richter, H, Ambrée, O, Lewejohann, L, Herring, A, Keyvani, K, Paulus, W, Palme, R, Touma, C, Schäbitz, WR, and Sachser, N. . “Wheel-Running in a Transgenic Mouse Model of Alzheimer's Disease: Protection or Symptom?” Behavioural Brain Research, № 190 (1): 74–84. doi: 10.1016/j.bbr.2008.02.005.
SH, Richter. . Was ist Glück?,, edited by B Heller.