Evidence-Based Adjunctive Treatments

Edited by: William T. O’Donohue and Nicholas A. Cummings
Elsevier 2008, ISBN: 978-0-12-088520-6

Evidence-Based Adjunctive Treatments, in which patients are provided additional modalities that can assist in their behavior change or the maintenance of their behavior change (i.e. telehealth, psychoeducation, consumer-driven treatment planning), have a useful role in addressing problems that can’t be solved by face-to-face meetings. The adjunctive therapies covered in this book are all based on improving patient’s self management of their problems or the factors that exacerbate their problems. The book is broadly organized into two sections. The first gives a broad overview of the major adjunctive modalities and the second concentrates on a systematic description of their role in the treatment of a number of special populations while providing practical suggestions for the timing and coordination for the use of the adjunctive therapies discussed in the book.

Drugs and the Future: Brain Science, Addiction and Society

Edited by: David Nutt, Trevor W. Robbins, Gerald V. Stimson,
Martin Ince and Andrew Jackson. Elsevier 2007, ISBN: 978-0-12-370624-9

Drugs and the Future presents 13 reviews collected to present the new advances in all areas of addiction research, including knowledge gained from mapping the human genome, the improved understanding of brain pathways and functions that are stimulated by addictive drugs, experimental and clinical psychology approaches to addiction and treatment, as well as both ethical considerations and social policy. The book also includes chapters on the history of addictive substances and some personal narratives of addiction. Introduced by Sir David King, Science Advisory to the UK Government and head of the Office of Science and Technology, and Nora Volkow, director of the National Institute on Drug Abuse in the USA, the book uniquely covers the full range of disciplines which can provide insight into the future of addiction, from genetics to the humanities. Written for a scientific audience, it is also applicable to non-specialists as well.

Heute wollen wir Sie aufmerksam machen auf : Encyclopedia of Heart Diseases, Academic Press 2006. 650 Seiten.

Drugs During Pregnancy and Lactation: Treatment options and risk assessment

Edited by: Christof Schaefer, Paul Peters and Richard K. Miller
Elsevier 2007, ISBN: 978-0-444-52072-2

Drugs During Pregnancy and Lactation is the resource for any practicing OB/GYN, family physician, midwife, or pharmacist who prescribes medicinal products to or evaluates environmental or occupational exposures in women who are or may become pregnant. Based on the highly successful seven German editions of this reference, the up-to-date drug listings have been revised into a handy pocket guide color tabbed for quick access to important information. Easy to reference each drug is listed discussing the side effects, general impact on organ systems, potential toxicity, and risks before offering dosage recommendations. It is the only book of its kind to provide conclusive information on treatments for diseases during pregnancy and lactation and actions to be taken after (inadvertant) exposure to drugs suspected to be developmentaly toxic. Unlike other dosage guides, this edition is an affordable, compact compendium of knowledge on the very latest drugs and their effects on pregnant/lactating women.

Drug-like Properties: Concepts, Structure Design and Methods: from ADME to Toxicity Optimization

Author(s): Edward H. Kerns and Li Di
Elsevier 2008, ISBN: 978-0-12-369520-8

Of the thousands of novel compounds that a drug discovery project team invents and that bind to the therapeutic target, typically only a fraction of these have sufficient ADME/Tox properties to become a drug product. Understanding ADME/Tox is critical for all drug researchers, owing to its increasing importance in advancing high quality candidates to clinical studies and the processes of drug discovery. If the properties are weak, the candidate will have a high risk of failure or be less desirable as a drug product. Drug-like Properties is a tool and resource for scientists engaged in, or preparing for, the selection and optimization process. The authors describe how properties affect in vivo pharmacological activity and impact in vitro assays. Individual drug-like properties are discussed from a practical point of view, such as solubility, permeability and metabolic stability, with regard to fundamental understanding, applications of property data in drug discovery and examples of structural modifications that have achieved improved property performance. The authors also review various methods for the screening (high throughput), diagnosis (medium throughput) and in-depth (low throughput) analysis of drug properties.

Evidence-Based Practice with Emotionally Troubled Children and Adolescents

Author: Morley D. Glicken, DSW.
Elsevier 2009, ISBN: 978-0-12-374523-1

At a time when increasing numbers of children are being treated for emotional problems, naming and treating those problems remains more of an art than a science often leaving children and their parents to navigate a confusing path. One reason for this uncertainty is that we have few objective ways of assessing a child’s emotional difficulties other than judgments based on interviews and checklists of symptoms. Unlike most adults, however, young children are often unable or unwilling to talk about their symptoms, leaving mental health professionals to rely on observation and information from parents and teachers that may be incorrect or biased. Furthermore, children develop so quickly that what looks like attention deficit disorder in the fall may look like anxiety or nothing at all in the summer. Although the mental health field has made great strides in helping children manage mental illness, particularly moderate conditions, the system of diagnosis is still ‚200 to 300 years behind other branches of medicine‘, according Dr. E. Jane Costello, a professor of psychiatry and behavioral sciences at Duke University. Dr. Costello and other experts believe that the search for a diagnosis is often a process of trial and error that may end with serious errors in diagnosis and treatment. According to government surveys at least six million American children have difficulties that are diagnosed as serious mental disorders, a number that has tripled since the early 1990s even though one of the largest continuing surveys of mental illness in children, tracking 4,500 children ages 9 to 13, found no cases of full-blown bi-polar disorder and only a few children with the mild flights of excessive energy that could be considered nascent bipolar disorder. Moreover, the symptoms diagnosed as serious emotional problems in children often bear little resemblance to those in adults. Instead, children’s moods often flip on and off throughout the day, and their upswings often look more like extreme agitation than bi-polar disorder. The confusion over accurate diagnosis and treatment leaves parents with very difficult children virtually alone and confused by the conflicting signals given by doctors and other mental health professionals. If parents are lucky, they may find a specialist who listens carefully and has the sensitivity to understand their child and their family. In dozens of interviews conducted by the author, however, parents of troubled children said that they had searched for months and sometimes years to find the right therapist. The advantage of EBP, according to Hines, is that it allows the practitioner to develop quality practice guidelines that can be applied to the client, identify appropriate literature that can be shared with the client, communicate with other professionals from a knowledge-guided frame of reference and, continue a process of self-learning that results in the best possible treatment for clients. Focusing on the most current research and best evidence regarding assessment, diagnosis, and treatment of children and adolescents with a range of emotional problems including, but not limited to: ADHD; Bi-Polar Disorder; anxiety and depression; eating disorders; Autism; Aspirgers Syndrome; substance abuse; social isolation; school related problems including underachievement; sexual acting out; Oppositional Defiant and Conduct Disorders; Childhood Schizophrenia; Gender Issues; Prolonged Grief; gang involvement; and, a number of other problems experienced by children and adolescents. Because concrete research evidence is often not used as the basis for practice with children and adolescents, and the next edition in the „DSM“ series, which promises more information about children isn’t due until 2011, Evidence-Based Practice with Emotionally Troubled Children and Adolescents provides a timely guide for practitioners, students, mental health professionals, and parents to a research-oriented approach for understanding and helping children experiencing emotional difficulties and their families. Particularly in populations where there has been a dramatic increase in troubled youth such as autism and substance abuse. The problems discussed in Evidence-Based Practice with Emotionally Troubled Children and Adolescents range from more common problems such as underachievement and parents who fail to supervise or provide effective role models to much more serious problems including Bi-Polar Disorder, Borderline Personality Disorder, and children traumatized by sexual abuse, violence, and neglect. Evidence-Based Practice with Emotionally Troubled Children and Adolescents fully covers assessment, diagnosis & treatment of children and adolescents, focusing on evidence-based practices; offers detailed how-to explanation of practical evidence-based treatment techniques; and, cites numerous case studies and provides integrative questions at the end of each chapter. Material related to diversity (including race, ethnicity, gender and social class) is integrated into each chapter.

Doing What Works in Brief Therapy (Second Edition): A Strategic Solution Focused Approach

Author(s): Ellen K. Quick
Elsevier 2009, ISBN: 978-0-12-374175-2

„>Doing What Works in Brief Therapy is both a set of procedures for the therapist and a philosophy – one that is shared with clients and one that guides the work of the therapist. This second edition continues its excellence in offering clinicians a guide to doing what works in brief therapy- for whom, and when and how to use it. Psychotherapy that follows these guidelines validates the client?s most important concerns – and it often turns out to be surprisingly brief. Author, Ellen Quick integrates strategic and solution focused therapy and includes guidelines for tailoring technique and interventions to client characteristics and preferences. With clinically rich examples throughout, this book offers applications for couples, including indications for individual or conjoint sessions.

Diffusion MRI: From Quantitative Measurement to In vivo Neuroanatomy

Edited by: Heidi Johansen-Berg and Timothy E.J. Behrens
Elsevier 2009, ISBN: 978-0-12-374709-9

Diffusion MRI is a magnetic resonance imaging (MRI) method that produces in vivo images of biological tissues weighted with the local microstructural characteristics of water diffusion, providing an effective means of visualizing functional connectivities in the nervous system. This book is the first comprehensive reference promoting the understanding of this rapidly evolving and powerful technology and providing the essential handbook for designing, analyzing or interpreting diffusion MR experiments. The book presents diffusion imaging in the context of well-established, classical experimental techniques, so that readers will be able to assess the scope and limitations of the new imaging technology with respect to techniques available previously. All chapters are written by leading international experts and cover methodology, validation of the imaging technology, application of diffusion imaging to the study of variation and development of normal brain anatomy, and disruption to the white matter in neurological disease or psychiatric disorder. The key features: the first comprehensive reference on a powerful technique in Brain Imaging; contributions from the key scientists in the field, including pioneers of the field Peter Basser (NIH), Susumu Mori (Johns Hopkins University), and others; describes the physical foundations, methods for quantitative analysis, and how the technique is applied to the cutting edge analysis of connections in the brain; and, full color throughout, carefully edited for clarity in style. (Amazon)

Current Topics in Developmental Biology

Vol 30 – Vol 87, z.B.:
– Development of Neural Circuitry
– Evolution and Development
– Ciliary Function in Mammalian Development
– Mouse Models of Developmental Genetic Disease
– Sex Determination and Sexual Development
– Red Cell Development
– Multiscale Modeling of Developmental Systems
– The Mitochondrion in the Germline and Early Development
– In Vivo Cellular and Molecular Imaging
– Neural Development
– Developmental Vascular Biology
– Stem Cells in Development and Disease
– The Centrosome in Cell Replication and Early Development
– Somitogenesis
– Cytoskeletal Mechanisms during Animal Development

Current Topics in Developmental Biology provides a comprehensive survey of the major topics in the field of developmental biology. The volumes are valuable to researchers in animal and plant development, as well as to students and professionals who want an introduction to cellular and molecular mechanisms of development. The series has recently passed its 30-year mark, making it the longest-running forum for contemporary issues in developmental biology. Volume 68, the most recent publication in Current Topics in Developmental Biology, not only discusses the most up-to-date discoveries, it includes 46 figures and 7 tables, all in full color. This volume touches upon topics such as Prolactin and Growth Hormone Signaling; Corpus Luteum Development: Lessons from Genetic Models in Mice; Comparative Developmental Biology of the Mammalian Uterus; Sarcopenia of Aging and its Metabolic Impact; and even a chapter on Initial failure in Myoblast Transplantation Therapy has led the way towards the isolation of muscle stem cells: Potential for tissue regeneration.

Crime Reconstruction

Author(s): W.Jerry Chisum, BS, and Brent E. Turvey, MS
Elsevier 2007, 587 Seiten
ISBN: 978-0-12-369375-4

Crime Reconstruction is a working guide to the interpretation of physical evidence, designed for the forensic generalist and those with multiple forensic specialties. It was developed to aid these forensic reconstructionists with the formulation of hypotheses and conclusions that stay within the known limits of forensic evidence. Crime Reconstruction begins with chapters on the history and ethics of crime reconstruction, and then shifts to the more applied subjects of general reconstruction methods and practice standards. It concludes with chapters on courtroom conduct and evidence admissibility, to prepare forensic reconstructionists for what awaits them when they take the witness stand. Crime Reconstruction is a watershed collaborative effort by internationally known, qualified and respected forensic science practitioners with generations of case experience. Forensic pioneers such as John D. DeHaan, John I. Thornton, and W. Jerry Chisum contribute chapters on arson reconstruction, trace evidence interpretation, advanced bloodstain interpretation, and reconstructionist ethics. Other chapters cover the subjects of shooting incident reconstruction, interpreting digital evidence, staged crime scenes, and examiner bias. Rarely have so many forensic giants collaborated, and never before have the natural limits of physical evidence been made so clear.