Prof. Dr. Joachim Jose
Chemistry and Pharmacy, Institute of Pharmaceutical and Medicinal Chemistry
Research Topics
Assay development and inhibitor testing, whole cell biocatalysts for synthesis of drugs and building blocks, directed evolution of enzyme inhibitors and biocatalysts, biosensor development and diagnostic tools, enzymatic transformation of plant biomass to basic chemicals, biotechnology-based sustainable chemistry, enzyme recycling
Prospective dissertation projects
- Natural compounds as inhibitors of human protein kinase CK2, in silico, in vitro and in cellulo studies
- Inhibition of HSP90 dimerization by natural compounds as a target in cancer and fungal diseases
- Anti-inflammatory effects of natural compound with regard to cytokine expression and TLR4-signaling