Name: Dr. Siva Krishna Mohan Nalluri
Diploma / M.Sc degree: University of Hyderabad, India
(June 2008)

PhD Project: Stimuli-responsive supramolecular interactions of nanoparticles and vesicles


Homepage: http://www.uni-muenster.de/Chemie.oc/ravoo/group.html

Abstract of Research Project

Ever since the discovery of cyclodextrins (CDs), it has been known that they form inclusion complexes with hydrophobic molecules due to their structure. Some recent reports have demonstrated that amphiphilic CDs form vesicles in aqueous medium. The surface of CD vesicles displays hydrophobic cavities in a liquid crystalline array. These vesicles are able to recognize and bind hydrophobic guest molecules such as t-butylbenzyl and adamantyl derivatives and it became possible to attain intra and intervesicular complexation using orthogonal host-guest and metal-ligand interaction. Using this line of thought, my present aspire is to design supramolecular structures from nanoparticles and vesicles formed by CDs. In the sense that, these particles could lead to build stimuli- responsive supramolecular structures basically by changing the characteristics of guest molecule by photochemical switching, metal-ligand complexation, hydrogen bonding, etc. The interactions between these host and guest molecules will be investigated by Isothermal Titration Calorimetry (ITC), Transmission Electron Microscopy (TEM), Dynamic Light Scattering (DLS), UV-Vis and Fluorescence spectroscopy, etc.


Publications

S. K. M. Nalluri, J. Voskuhl, J. B. Bultema, E. J. Boekema, B. J. Ravoo
Light-responsive capture and release of DNA in a ternary supramolecular complex
Angew. Chem. 123 (2011), 9921-9925.
Angew. Chem. Int. Ed. 50 (2011), 9747-9751.

S. K. M. Nalluri, J. B. Bultema, E. J. Boekema, B. J. Ravoo
Metal ion responsive adhesion of vesicles by conformational switching of a non-covalent linker
Chem. Sci. 2 (2011), 2383-2391.

S. K. M. Nalluri, J. B. Bultema, E. J. Boekema, B. J. Ravoo
Photoresponsive Molecular Recognition and Adhesion of Vesicles in a Competitive Ternary Supramolecular System
Chem. Eur. J. 17 (2011), 10297–10303.

S. K. M. Nalluri, B. J. Ravoo
Lichtgesteuerte molekulare Erkennung und Adhäsion von Vesikeln
Angew. Chem. 122 (2010), 5499–5502.


Siva Krishna Mohan Nalluri
eMail: Siva Krishna Mohan Nalluri