• Forschungsschwerpunkte

    • Radiochemie und Radiopharmazie
    • Leitung der radiochemischen Produktion im Multiscale Imaging Centre

  • Akademische Ausbildung

    Promotion in Chemie (Dr.rer.nat.)
    Diplom Chemie

  • Publikationen

    2024

    Hoffgen KS, Dabel J, Konken CP, Depke DA, Hermann S, Dorner W, Schelhaas S, Schafers M, Mootz HD. Combining poly-epitope MoonTags and labeled nanobodies for signal amplification in cell-specific PET imaging in vivo. Nucl Med Biol 2024;136-137: 108937. Abstract

    2023

    Konken CP, Beutel B, Schinor B, Song J, Gerwien H, Korpos E, Burmeister M, Riemann B, Schafers M, Sorokin L, Haufe G. Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors. Bioorg Med Chem 2023;90: 117350. Abstract
    Paul Konken C, Beutel B, Schinor B, Song J, Gerwien H, Korpos E, Burmeister M, Riemann B, Schafers M, Sorokin L, Haufe G. Influence of N-arylsulfonamido d-valine N-substituents on the selectivity and potency of matrix metalloproteinase inhibitors. Bioorg Med Chem 2023;90: 117350. Abstract

    2022

    Honold L, Austrup M, Faust A, Konken CP, Schwegmann K, Zinnhardt B, Daniliuc CG, Haufe G, Schafers M, Kopka K, Hermann S. Towards Optimized Bioavailability of (99m)Tc-Labeled Barbiturates for Non-invasive Imaging of Matrix Metalloproteinase Activity. Mol Imaging Biol 2022;24: 434-443. Abstract
    Konken CP, Hessling K, Thale I, Schelhaas S, Dabel J, Maskri S, Bulk E, Budde T, Koch O, Schwab A, Schafers M, Wunsch B. Imaging of the calcium activated potassium channel 31 (KCa 31) in vivo using a senicapoc-derived positron emission tomography tracer. Arch Pharm (Weinheim) 2022: e2200388. Abstract
    Rosner L, Konken CP, Depke DA, Rentmeister A, Schafers M. Covalent labeling of immune cells. Curr Opin Chem Biol 2022;68: 102144. Abstract

    2021

    Brömmel K, Konken CP, Börgel F, Obeng-Darko H, Schelhaas S, Bulk E, Budde T, Schwab A, Schäfers M, Wünsch B. Synthesis and biological evaluation of PET tracers designed for imaging of calcium activated potassium channel 31 (K[sub:Ca]31) channels_in vivo_. RSC Adv. 2021;11: 30295-30304. Abstract
    Depke DA, Konken CP, Rosner L, Hermann S, Schafers M, Rentmeister A. A novel (18)F-labeled clickable substrate for targeted imaging of SNAP-tag expressing cells by PET in vivo. Chem Commun (Camb) 2021;57: 9850-9853. Abstract

    2020

    Brömmel K, Maskri S, Maisuls I, Konken CP, Rieke M, Petho Z, Strassert CA, Koch O, Schwab A, Wunsch B. Synthesis of Small-Molecule Fluorescent Probes for the In Vitro Imaging of Calcium-Activated Potassium Channel KCa 31. Angew Chem Int Ed Engl 2020;59: 8277-8284. Abstract

    2018

    Beutel B, Song J, Konken CP, Korpos E, Schinor B, Gerwien H, Vidyadharan R, Burmeister M, Li L, Haufe G, Sorokin L. New in Vivo Compatible Matrix Metalloproteinase (MMP)-2 and MMP-9 Inhibitors. Bioconjug Chem 2018;29: 3715-3725. Abstract
    Konken CP, Haufe G, Brömmel K, Wünsch B, Schäfers M, Wagner S, Hugenberg V. Development of symmetric O-BODIPYs with different optical properties as building blocks for the synthesis of ligands for multimodal imaging. Dyes Pigment. 2018;158: 88-96. Abstract

    2017

    Ortmeyer CP, Haufe G, Schäfers M, Wagner S, Schwegmann K, Hermann S, Hugenberg V. Development of 18F-fluorinated BODIPYs for multimodal imaging. J Label Compd Radiopharm 2017;60: 273. Abstract
    Ortmeyer CP, Haufe G, Schwegmann K, Hermann S, Schafers M, Borgel F, Wunsch B, Wagner S, Hugenberg V. Synthesis and evaluation of a [18F]BODIPY-labeled caspase-inhibitor. Bioorg Med Chem 2017;25: 2167-2176. Abstract