Original Papers

127. A.-K. Weishaupt, A. Gremme, T. Meiners, V. Schwantes, K. Sarnow, A. Thiel, T. Schwerdtle, M. Aschner, H. Hayen, J. Bornhorst, Redox Biochem. Chem. (2024) 100043.
Dysfunctional Copper Homeostasis in Caenorhabditis elegans affects genomic and neuronal stability

126. E. Rudt, C. Faist, V. Schwantes, N. Konrad, N. Wiedmaier-Czerny, K. Lehnert, S. Topman-Rakover, A. Brill,  S. Burdman, Z. Hayouka, W. Vetter, H. Hayen, Anal. Bioanal. Chem. 416 (2024) 5513-5525.
LC–MS/MS-based phospholipid profiling of plant-pathogenic bacteria with tailored separation of methyl-branched species

125. J. Scholz, E. Rudt, A. Gremme, C. M. Gaßmöller (née Wienken), J. Bornhorst, H. Hayen, Anal. Chim. Acta. 1317 (2024) 342913.
Hyphenation of supercritical fluid chromatography and trapped ion mobility-mass spectrometry for quantitative lipidomics

124. E. Rudt, S. Schneider, H. Hayen, J. Am. Soc. Mass Spectrom. 35 (2024) 1584-1593.
Hyphenation of liquid chromatography and trapped ion mobility–mass spectrometry for characterization of isomeric phosphatidylethanolamines with focus on N-acylated species

123. P. Dvořák, B. Burýšková, B. Popelarova, B. Ebert, T. Botka, D. Bujdoš, A. Sánchez-Pascuala, H. Schöttler, H. Hayen, V. de Lorenzo, L. M. Blank, M. Benesik, Nat. Commun. 15 (2024) 2666.
Synthetically-primed adaptation of Pseudomonas putida to a non-native substrate D-xylose

122. K. E. Ebert, P. Griem, T. Weiss, T. Brüning, H. Hayen, H. M. Koch, D. Bury, Arch. Toxicol. 98 (2024) 1383-198.
Toxicokinetics of homosalate in humans after dermal application: applicability of oral-route-data for exposure assessment by human biomonitoring

121. T. Tiso, G. Welsing, A. Lipphardt, D. F. Sauer, Z.-M. Chi, L. M. Blank, H. Hayen, J. Surfactants Deterg. 27 (2024) 459-461.
Proposal for a systematic naming convention for liamocins

120. S. A. Wrobel, S. Koslitz, D. Bury, H. Hayen, H. Koch, T. Brüning, H. U. Käfferlein, Front. Public Health - Occupational Health and Safety (2024) Front. Public Health 11:1321138.
Human biomonitoring of neonicotinoid exposures: case studies after use of a spray-agent on ornamental plants and a topical medication on pets

119. K. E. Ebert, V. N. Belov, M. John, T. Weiss, T. Brüning, H. Hayen, H. M. Koch, D. Bury, Chem. Res. Toxicol. 37 (2024) 287-291.
Identification, organic synthesis, and sensitive analysis of a cis-homosalate-specific exposure biomarker

118. M. Kubot, L. Balke, J. Scholz, S. Wiemers-Meyer, U. Karst, H. Hayen, H. Hur, M. Winter, J. Kasnatscheew, S. Nowak, Adv. Sci. 11 (2024) 2305282.
High-voltage instability of vinylene carbonate (VC): impact of formed poly-VC on interphases and toxicity

117. S. A. Wrobel, D. Bury, S. Koslitz, H. Hayen, H. M. Koch, T. Brüning, H. U. Käfferlein, Environ. Sci. Technol. 57 (2023) 19285-19294.
Quantitative metabolism and urinary elimination kinetics of seven neonicotinoids and neonicotinoid-like compounds in humans

116. A. Lipphardt, T. Karmainski, L. M. Blank, H. Hayen, T. Tiso, Anal. Bioanal. Chem. 415 (2023) 7067–7084.
Identification and quantification of biosurfactants produced by the marine bacterium Alcanivorax borkumensis by hyphenated techniques

115. S. Schneider, S. Hammann, H. Hayen, J. Agric. Food Chem. 71 (2023) 11263−11275.
Determination of polar lipids in wheat and oat by a complementary approach of hydrophilic interaction liquid chromatography (HILIC) and reversed-phase HPLC hyphenated with high-resolution mass spectrometry

114. P. Dvořák, B. Burýšková, B. Popelářová, B. Ebert, T. Botka, D. Bujdoš, A. Sánchez-Pascuala, H. Schöttler, H. Hayen, V. de Lorenzo, L. M. Blank, M. Benešík, preprint on bioRxiv.
Genomic and metabolic plasticity drive alternative scenarios for adapting Pseudomonas putida to non-native substrate D-xylose

113. E. Rudt, M. Feldhaus, C. G. Margraf, S. Schlehuber, A. Schubert, S. Heuckeroth, U. Karst, V. Jeck, S. W. Meyer, A. Korf, H. Hayen, Anal. Chem. 95 (2023) 9488−9496.
Comparison of data-dependent acquisition, data-independent acquisition, and parallel reaction monitoring in trapped ion mobility spectrometry−time-of-flight tandem mass spectrometry-based lipidomics

112. M.-T. Nguyen, Z. Hu, M. Mohammad, H. Schöttler, S. Niemann, M. Schultz, K. Barczyk-Kahlert, T. Jin, H. Hayen, M. Herrmann, Microbiol. Spectr. (2023) 11(3):e0429322.
Bacterial lipoproteins shift cellular metabolism to glycolysis in macrophages causing bone erosion

111. S. A. Wrobel, S. Koslitz, V. N. Belov, D. Bury, H. Hayen, T. Brüning, H. M. Koch, H. U. Käfferlein, Environ. Res. 226 (2023) 115609.
Quantitation of 6-chloronicotinic acid and 2-chloro-1,3-thiazole-5-carboxylic acid and their glycine conjugates in human urine to assess neonicotinoid exposure

110. R. Schmid, S. Heuckeroth, A. Korf, A. Smirnov, O. Myers, T. Dyrlund, R. Bushuiev, K. J. Murray, N. Hoffmann, M. Lu, A. Sarvepalli, Z. Zhang, M. Fleischauer, K. Dührkop, M. Wesner, S. Hoogstra, E. Rudt, O. Mokshyna, C. Brungs, K. Ponomarov, L. Mutabdžija, T. Damiani, C. J. Pudney, M. Earll, P. O. Helmer, T. Fallon, T. Schulze, A. Rivas-Ubach, A. Bilbao, H. Richter, L.-F. Nothias, M. Wang, M. Orešič, J.-K. Weng, S. Böcker, A. Jeibmann, H. Hayen, U. Karst, P. Dorrestein., D. Petras, X. Du, T. Pluskal, Nat. Biotech. 41 (2023) 447-449.
Integrative analysis of multimodal mass spectrometry data in MZmine 3

109. B. Blume, V. Schwantes, M. Witting, H. Hayen, P. Schmitt-Kopplin, P. O. Helmer, B. Michalke, J. Proteome Res. 22 (2023) 837-850.
Lipidomic and metallomic alteration of Caenorhabditis elegans after acute and chronic manganese, iron and zinc exposure with link to neurodegenerative disorders

108. M. Froning, C. Grütering, L. M. Blank, H. Hayen, Rapid Commun. Mass Spectrom. 37 (2023) e9457.
Determination of double bond positions in methyl ketones by gas chromatography–mass spectrometry using dimethyl disulfide derivatives

107. S. A. Wrobel, D. Bury, V. N. Belov, J. M. Klenk, B. Hauer, H. Hayen, A. J. Martino-Andrade, H. M. Koch, T. Brüning, H. U. Käfferlein, Anal. Chim. Acta 1239 (2023) 340680.
Rapid quantification of seven major neonicotinoids and neonicotinoid-like compounds and their key metabolites in human urine

106. K. E. Ebert, P. Griem, T. Weiss, T. Brüning, H. Hayen, H. M. Koch, D. Bury, Environ. Int. (2022) 107637.
Diastereoselective metabolism of homomenthyl salicylate (homosalate): identification of relevant human exposure biomarkers

105. C. Brungs, R. Schmid, C. Wolf, T. Berg, A. Korf, S. Heuckeroth, H. Hayen, S. van der Bent, K. Maijer, T. Rustemeyer, U. Karst, Anal. Chem. 94 (2022) 3581-3589.
Tattoo pigment identification in inks and dkin biopsies of adverse reactions by complementary elemental and molecular bioimaging with mass spectral library matching

104. M. Schultz , M. Mohammad , M.-T. Nguyen , Z. Hu , A. Jarneborn, C. M. Wienken, M. Froning, R. Pullerits , A. Ali, H. Hayen , F. Götz, T. Jin, Front. Microbiol. in press (doi: 10.3389/fmicb.2022.843799)
Lipoproteins cause bone resorption in a mouse model of Staphylococcus aureus septic arthritis

103. S. A. Wrobel, D. Bury, H. Hayen, H. M. Koch, T. Brüning, H. U. Käfferlein, Arch. Toxicol. 96 (2021) 121134.
Human metabolism and urinary excretion of seven neonicotinoids and neonicotinoid-like compounds after controlled oral dosages

102. B. Ringbeck, V. N. Belov, C. Schmidtkunz, K. Küpper, W. Gries, T. Weiss, T. Brüning, H. Hayen, D. Bury, G. Leng, H. M. Koch, Chem. Res. Toxicol. 34 (2021) 2392-2403.
Human metabolism and urinary excretion kinetics of nonylphenol in three volunteers after a single oral dose

101. J. Scholz, P. O. Helmer, M. M. Nicolai, J. Bornhorst, H. Hayen, J. Chromatogr. A. (2021) 462481.
Profiling of sphingolipids in Caenorhabditis elegans by two-dimensional multiple heart-cut liquid chromatography – mass spectrometry

100. K. E. Ebert, V. N. Belov, T. Weiss, T. Brüning, H. Hayen, H. M. Koch, D. Bury, Anal. Chim. Acta 1176 (2021) 338754.
Determination of Urinary Metabolites of the UV Filter Homosalate by Online-SPE-LC-MS/MS

99. K. Gianmoena, N. Gasparoni, A. Jashari, P. Gabrys, K. Grgas, A. Ghallab, K. Nordström, G. Gasparoni, J. Reinders, K. Edlund, P. Godoy, A. Schriewer, H. Hayen, C. A. Hudert, G. Damm, D. Seehofer, T. S. Weiss, P. Boor, H.-J. Anders, M. Motrapu, P. Jansen, T. S. Schiergens, M. Falk-Paulsen, P. Rosenstiel, C. Lisowski, E. Salido, R. Marchan, J. Walter, J. G. Hengstler, C. Cadenas, Cell Rep. 36 (2021) 109526.
Epigenetic and transcriptional profiling identifies impaired glyoxylate detoxification in NAFLD as a risk factor for hyperoxaluria

98. B. Ringbeck, D. Bury, H. Hayen, T. Weiss, T. Brüning, H. M. Koch, J. Chromatogr. B. 1177 2021) 122794.
Determination of specific urinary nonylphenol metabolites by online-SPE-LC-MS/MS as novel human exposure biomarkers

97. R. Schmid, D. Petras, L.-F. Nothias, M. Wang, A. Aron, A. Jagels, H. Tsugawa, J. Rainer, M. Garcia-Aloy, K. Dührkop, A. Korf, T. Pluskal, Z. Kamenik, A. Jarmusch, A. Caraballo-Rodriguez, K. Weldon, M. Nothias-Esposito, A. Aksenov, A. Bauermeister, A. Albarracin Orio, C. Grundmann, F. Vargas, I. Koester, J. Gauglitz, E. Gentry, Y. Hövelmann, S. Kalinina, M. Pendergraft, M. Panitchpakdi, R. Tehan, A. Le Goullec, G. Aleti, H. Mannochio Russo, B. Arndt, F. Hübner, H. Hayen, H. Zhi, M. Raffatellu, K. Prather, L. Aluwihare, S. Böcker, K. McPhail, H.-U. Humpf, U. Karst, P. Dorrestein, Nat. Commun. 12 (2021) 3832.
Ion identity molecular networking for mass spectrometry-based metabolomics in the GNPS environment

96. B. Ringbeck, D. Bury, A. Gotthardt, H. Hayen, R. Otter, T. Weiss, T. Brüning, H. M. Koch, Toxicol. Lett. 343 (2021) 11-20.
Human metabolism and urinary excretion kinetics of di-n-butyl adipate (DnBA) after oral and dermal administration in three volunteers

95. P. O. Helmer, I. D. Nordhorn, A. Korf, A. Behrens, R. Buchholz, F. Zubeil, U. Karst, H. Hayen, Anal. Chem. 93 (2021) 2135-2143.
Complementing Matrix-Assisted Laser Desorption Ionization-mass spectrometry imaging with chromatography data for improved assignment of isobaric and isomeric phospholipids utilizing trapped ion mobility-mass spectrometry

94. P. O. Helmer, M. M. Nicolai, V. Schwantes, J. Bornhorst, H. Hayen, Free Radical Biol. Med. 162 (2021) 216-224.
Investigation of cardiolipin oxidation products as a new endpoint for oxidative stress in C. elegans by means of online two-dimensional liquid chromatography and high-resolution mass spectrometry

93. J. Henschel, H. Hayen, MethodsX 7 (2020) 101134.
Application of large volume injection for sensitive LC-MS/MS analysis of seven artificial sweeteners in surface waters

92. K. Scholz, A. Lipphardt, C. M Wienken, T. Tiso, H. Hayen, J. Chromatogr. A. 1631 (2020) 461584.
Hyphenation of supercritical fluid chromatography with different detection methods for identification and quantification of liamocin biosurfactants

91. M. Baune, K. Kang, W. D. C. Schenkeveld, S. M. Kraemer, H. Hayen, G. Weber, BioMetals, 33 (2020) 305-321.
Importance of oxidation products in coumarin-mediated Fe(hydr)oxide mineral dissolution

90. P. O. Helmer, A. Behrens, E. Rudt, U. Karst, H. Hayen, Anal. Chem. 92 (2020) 12010-12016.
Hydroperoxylated vs. di-hydroxylated lipids: differentiation of isomeric cardiolipin oxidation products by multidimensional separation techniques

89. M. Froning, P. O. Helmer, H. Hayen, Rapid Commun. Mass Spectrom. 34 (2020) e8897.
Identification and structural characterization of lipid A from Escherichia coli, Pseudomonas putida and Pseudomonas taiwanensis by liquid chromatography coupled to high resolution‐tandem mass spectrometry

88. K. Scholz, M. Seyfried, O. Brumhard, L. M. Blank, T. Tiso, H. Hayen. J. Chromatogr. A. 1627 (2020) 461404.
Comprehensive liamocin biosurfactants analysis by reversed phase liquid chromatography coupled to mass spectrometric and charged-aerosol detection

87. V. Jeck, M. Froning, T. Tiso, L. M. Blank, H. Hayen. Anal. Bioanal. Chem. 412 (2020) 5601-56013.
Double bond localization in unsaturated rhamnolipid precursors 3-(3-hydroxyalkanoyloxy)alkanoic acids by liquid chromatography-mass spectrometry applying online Paternò-Büchi reaction

86.  B. Ringbeck, D. Bury, H. Hayen, T. Weiss, T. Brüning, H. M. Koch, J. Chromatogr. B. 1141 (2020) 122029.
Determination of di-n-butyl adipate (DnBA) metabolites as possible biomarkers of exposure in human urine by online-SPE-LC-MS/MS

85. P. O. Helmer, C. M. Wienken, A. Korf, H. Hayen. J. Chromatogr. A. (2020) 460918.
Mass spectrometric investigation of cardiolipins and their oxidation products after two-dimensional heart-cut liquid chromatography

84. A. Germer, T. Tiso, C. Mueller, B. Behrens, C. Vosse, K. Scholz, M. Froning, H. Hayen, L. M. Blank, Appl. Environ. Microbiol. (2020) 86:e02317-19.
Exploiting the natural diversity of the acyltransferase RhlA for the synthesis of the rhamnolipid precursor 3-(3-hydroxyalkanoyloxy)alkanoic acid

83. A. Korf, S. Hammann, R. Schmid, M. Froning, H. Hayen, L. J. E. Cramp, Sci. Rep. 10 (2020) 767.
Digging deeper - A new data mining workflow for improved processing and interpretation of high resolution GC-Q-TOF MS data in archaeological research

82. C. Vosse, G. M. Thyssen, M. Sperling, U. Karst, H. Hayen, Anal. Sci. Adv. 1 (2020) 46-55.
Complementary approach for analysis of phospholipids by liquid chromatography hyphenated to elemental and molecular mass spectrometry

81. A. Korf, T. Fouquet, R. Schmid, H. Hayen, S. Hagenhoff, Anal. Chem. 92 (2020) 628-633.
Expanding the Kendrick mass plot toolbox in MZmine 2 to enable a rapid polymer characterization in liquid chromatography-mass spectrometry data sets

80. P. O. Helmer, A. Korf, H. Hayen, Rapid Commun. Mass Spectrom. (2020) 34:e8566.
Analysis of artificially oxidized cardiolipins and monolyso-cardiolipins via LC HRMS and Kendrick mass plots after HILIC-based sample preparation

79. M. Palomo-Guerrero, R. Fado, M. Casas, M. Pérez-Montero, M. Baena, P. O. Helmer, J. L. Domínguez, A. Roig, D. Serra, H. Hayen, H. Stenmark, C. Raiborg, N. Casals, eLife (2019) 8:e51063.
Sensing of nutrients by CPT1C regulates late endosome/lysosome anterograde transport and axon growth

78. A. Korf, V. Jeck, R. Schmid. P. O. Helmer, H. Hayen, Anal. Chem., 91 (2019) 5098-5105.
Lipid Species Annotation at Double Bond Position Level with Custom Databases by Extension of the MZmine 2 Open-Source Software Package

77. K. M. Saur, O. Brumhard, K. Scholz, H. Hayen, T. Tiso, Appl. Microbiol. Biotechnol. 103 (2019) 4741-4752. 
A pH shift induces high titer liamocin production in Aureobasidium pullulans

76. C. Cadenas, S. Vosbeck, K. Edlund, K. Grgas, K. Madjar, B. Hellwig, A. Adawy, J. D. Stewart, M. Lesjak, D. Franckenstein, M. Claus, H. Hayen, A. Schriewer, K. Gianmoena, S. Thaler, M. Schmidt, P. Micke, F. Pontén, A. Mardinoglu, C. Zhang, H. U. Käfferlein, C. Watzl, S. Frank, J. Rahnenführer, R. Marchan, and J. G. Hengstler, Int. J. Cancer 145 (2019) 901-915. 
LIPG-promoted lipid storage mediates adaptation to oxidative stress in breast cancer

75. S. Hammann, A. Korf, I. D. Bull, H. Hayen, L. J. E. Cramp, Food Chem. 282 (2019) 27-35. 
Lipid profiling and analytical discrimination of seven cereals using high temperature gas chromatography coupled to high resolution quadrupole time-of-flight mass spectrometry

74. V. Jeck, A. Korf, C. Vosse, H. Hayen, Rapid Commun. Mass Spectrom. 33 (S1) (2019) 86-94. 
Localization of double bond positions in lipids by tandem mass spectrometry succeeding high performance liquid chromatography with post‐column derivatization

73. S. Müller-Bomke, M. Sperling, H. Hayen, U. Karst, Z. Naturforsch. B, (2018) 73(11)b (2018) 781-791. 
Biolabeling with cobaltocinium tags

72. K. Scholz, T. Tiso, L. M. Blank, H. Hayen, BioMetals, 31 (2018) 785-795. 
Mass spectrometric characterization of siderophores produced by Pseudomonas taiwanensis VLB120 assisted by stable isotope labeling of nitrogen source

71. C. Vosse, C. Wienken, C. Cadenas, H. Hayen, J. Chromatogr. A., 1565 (2018) 105-113.
Separation and identification of phospholipids by hydrophilic interaction liquid chromatography coupled to tandem high resolution mass spectrometry with focus on isomeric phosphatidylglycerol and bis(monoacylglycero)phosphate

70. S. Hagenhoff, H. Hayen, Anal. Bioanal. Chem. 410 (2018) 4905-4911.
LC/MS analysis of vitamin D metabolites by dielectric barrier discharge ionization and a comparison with electrospray ionization and atmospheric pressure chemical ionization

69. S. Hagenhoff, A. Korf, U. Marggraf, S. Brandt, A. Schütz, J. Franzke, H. Hayen, Rapid Commun. Mass Spectrom. 32 (2018) 1092-1098.
Screening of semifluorinated n-alkanes by gas chromatography coupled to dielectric barrier discharge ionization-mass spectrometry (GC/DBDI-MS)

68. A. Korf, C. Vosse, R. Schmid, P. O. Helmer, V. Jeck, H. Hayen, Rapid Commun. Mass Spectrom. 32 (2018) 981-991.
Three-dimensional Kendrick mass plots as a tool for lipid identification

67. J. T. Shelley, S. P. Badal, C. Engelhard, H. Hayen, Anal. Bioanal. Chem. 410 (2018) 4061-4076.
Ambient desorption/ionization mass spectrometry: Evolution from rapid qualitative screening to accurate quantification tool

66. D. Bury, V. N. Belov, Y. Qi, H. Hayen, D. A. Volmer, T. Brüning, H. M. Koch, Anal. Chem., 90 (2018) 944-951.
Determination of urinary metabolites of the emerging UV filter Octocrylene by online-SPE-LC-MS/MS

65. F. Lessmann, D. Bury, T. Weiss, H. Hayen, T. Brüning, H. M. Koch, Biomarkers 23 (2018) 196-206.
De-novo identification of specific exposure biomarkers of the alternative plasticiser di(2-ethylhexyl)terephthalate (DEHTP) after low oral dosage to male volunteers by HPLC-Q-Orbitrap-MS

64. T. Tiso, R. Zauter, H. Tulke, B. Leuchte, W.-J. Li, B. Behrens, A. Wittgens, F. Rosenau, H. Hayen, L. M. Blank, Microb. Cell Fact. (2017) 16:225.
Designer rhamnolipids by reduction of congener diversity – production and characterization

63. A. Schriewer, M. Brink, K. Gianmoena, C. Cadenas, H. Hayen, J. Chromatogr. B, 1068-1069 (2017) 239-244.
Oxalic acid quantification in mouse urine and primary mouse hepatocyte cell culture samples by ion exclusion chromatography-mass spectrometry

62. A. Schriewer, C. Cadenas, H. Hayen, J. Sep. Sci., 40 (2017) 4303-4310.
Hydrophilic interaction liquid chromatography tandem mass spectrometry analysis of malonyl-coenzyme A in breast cancer cell cultures applying online solid phase extraction

61. M. Baune, Y. Qi, K. Scholz, D. A. Volmer, H. Hayen, BioMetals, 30(2017) 589-597.
Structural characterization of pyoverdines produced by Pseudomonas putida KT2440 and Pseudomonas taiwanensis VLB120

60. S. Hagenhoff, J. Franzke, H. Hayen, Anal. Chem., 89 (2017) 4210-4215.
Determination of peroxide explosive TATP and related compounds by dielectric barrier discharge ionization-mass spectrometry (DBDI-MS)

59. B. Behrens, P. O. Helmer, T. Tiso, L. M. Blank, H. Hayen, J. Chromatogr. A., 1465 (2016) 90-97.
Rhamnolipid biosurfactant analysis using online turbulent flow chromatography-liquid chromatography-tandem mass spectrometry

58.  T. Tiso, P. Sabelhaus, B. Behrens, A. Wittgens, F. Rosenau, H. Hayen, L. M. Blank, Metab. Eng. Commun., 3 (2016) 234-244.
Creating metabolic demand as an engineering strategy in Pseudomonas putida - rhamnolipid synthesis as an example

57. B. Behrens, M. Baune, J. Jungkeit, T. Tiso, L. M. Blank, H. Hayen, J. Chromatogr. A., 1455 (2016) 125-132.
High performance liquid chromatography-charged aerosol detection applying an inverse gradient for quantification of rhamnolipid biosurfactants

56. B. Behrens, J. Engelen, T. Tiso, L. M. Blank, H. Hayen, Anal. Bioanal. Chem., 408 (2016) 2505-2514.
Characterization of rhamnolipids by liquid chromatography/mass spectrometry after solid-phase extraction

55. Y. Qui, H. Hayen, D. A. Volmer, BioMetals, 29 (2016) 53-60. 
Characterization of the iron-binding properties of pyoverdine using electron-capture dissociation-tandem mass spectrometry

54. Y. E. Silina, C. Fink-Straube, H. Hayen, D. A. Volmer, Anal. Methods, 7 (2015) 3701-3707. 
Analysis of fatty acids and triacylglycerides by Pd nanoparticle-assisted laser desorption/ionization mass spectrometry

53. O. Wegener, G. Harms, D. A. Volmer, H. Hayen, Drug. Test. Anal., 7 (2015) 773-779.
Structural characterization of a degradation product of rocuronium using nanoelectrospray-high resolution mass spectrometry

52. S. Krieger, H. Hayen, O. J. Schmitz, Anal. Bioanal. Chem., 405 (2013) 8337-8345.
Quantification of coumarin in cinnamon and woodruff-beverages using DIP-APCI-MS and LC-MS

51. B. Gilbert-López, M. Schilling, N, Ahlmann, A. Michels, H. Hayen, A. Molina-Díaz, J. F. García-Reyes, J. Franzke, Anal. Chem., 85 (2013) 3174-3182.
Ambient diode laser desorption dielectric barrier discharge ionization mass spectrometry of non-volatile chemicals

50. T. Gronemeyer, S. Wiese, R. Ofman, C. Bunse, M. Pawlas, H. Hayen, M. Eisenacher, C. Stephan, H. E. Meyer, H. R. Waterham, E. Erdmann, R. J. Wanders, B. Warscheid, PLoS ONE 8 (2013) e57395.
The proteome of human liver peroxisomes: Identification of five new peroxisomal constituents by a label-free quantitative proteomics survey.

49. B. Gilbert-López, H. Geltenpoth, C. Meyer, A. Michels, H. Hayen, A. Molina-Díaz, J. F. García-Reyes, J. Franzke, Rapid Commun. Mass Spectrom., 27 (2013) 419-429.
Performance of dielectric barrier discharge ionization mass spectrometry for pesticide testing: A comparison with APCI and electrospray

48. B. Gilbert-López, J. F. García-Reyes, C. Meyer, A. Michels, J. Franzke, A. Molina-Díaz, H. Hayen, Analyst, 127 (2012) 5403-5410.
Simultaneous testing of multiclass organic contaminants in food and environment by liquid chromatography/dielectric barrier discharge ionization-mass spectrometry

47. G. Dierkes, A. Bongartz, H. Guth, H. Hayen, J. Agric. Food Chem., 60 (2012), 394-401.
Quality evaluation of olive oil by statistical analysis of multicomponent stable isotope dilution assay data of aroma active compounds

46. J. Rühl, E.-M. Hein, H. Hayen, A. Schmid, L. M. Blank, Microb. Biotechnol., 5 (2012) 45-58.
The glycerophospholipid inventory of Pseudomonas putida is conserved between strains and enables growth condition related alterations

45. C. Cadenas, S. Vosbeck, E.-M. Hein, B. Hellwig, A. Langer, H. Hayen, B. Geppert, S. El-Kariem, R. Marchan, M. Hermes, J. Rahnenführer, B. Peksel, T. Török, L. Vígh, J. G. Hengstler, Biochim. Biophys. Acta, 1821 (2012) 1256-1268.
Glycerophospholipid profile in oncogene-induced senescence

44. E.- M. Hein, H. Hayen, Metabolites, 2 (2012) 254-267.
Comparative lipidomic profiling of S. cerevisiae and four other hemiascomycetous yeasts

43. L. M. Blank, R. R. Desphande, A. Schmid, H. Hayen, Anal. Bioanal. Chem, 403 (2012) 2291-2305.
Analysis of carbon and nitrogen cometabolism in yeast by ultrahigh-resolution mass spectrometry applying 13C- and 15N-labeled substrates simultaneously

42. G. Dierkes, S. Krieger, R. Dück, A. Bongartz, O. J. Schmitz, H. Hayen, J. Agric. Food Chem., 60 (2012) 7597-7606.
HPLC-MS profiling of phenolic compounds for evaluation of olive oil bitterness and pungency

41. J. Köster, H. Hayen, N. von Wirén, G. Weber, Electrophoresis, 32 (2011) 772-781.
Isoelectric focusing of small non-covalent metal species in plants

40. L. Wäntig, N. Jakubowski, H. Hayen, P. H. Roos, J. Anal. At. Spectrom., 26 (2011) 1610-1618.
Iodination of proteins, proteomes and antibodies with potassium triodide for LA-ICP-MS based proteomic analyses

39. A. Polatajko, I. Feldmann, H. Hayen, N. Jakubowski, Metallomics, 3 (2011) 1001-1008.
Combined application of a laser ablation-ICP-MS assay for screening and ESI-FTMS for identification of a Cd-binding protein in Spinacia oleracea L. after exposure to Cd

38. M. Siemerink, N. H. Schebb, A. Liesener, A.-M. Perchuc, R. Schöni, M. Wilmer, H. Hayen, U. Karst, M. Vogel, Rapid Commun. Mass Spectrom., 24 (2010) 687-697.
Development of a fast liquid chromatography/mass spectrometry screening method for angiotensin-converting enzyme (ACE) inhibitors in complex natural mixtures like snake venom

37. M. Bataineh, U. Luebcke-Von Varel, H. Hayen, W. Brack, J. Am. Soc. Mass Spectrom., 21 (2010) 1016-1027.
HPLC/APCI-FTICR-MS as a tool for identification of mutagenic polar compounds in effect-directed analysis

36. E.-M. Hein, B. Bödecker, J. Nolte, H. Hayen, Rapid Commun. Mass Spectrom., 24 (2010) 2083-2092.
Software tool for mining liquid chromatography / multi stage mass spectrometry data for comprehensive phospholipid profiling

35. T. Steinkamp, H. Hayen, J. Huskens, U. Karst, Inorg. Chim. Acta, 362 (2009) 421-425.
Lanthanide-catalyzed hydrolysis of 4,7-diphenyl-1,10-phenanthroline-2,9-dicarboxylic acid esters

34. K. S. Rabe, M. Spengler, M. Erkelenz, J. Müller, V. J. Gandubert, H. Hayen, C. M. Niemeyer, ChemBioChem, 10 (2009) 751-757.
Screening for cytochrom P450 reactivity harnessing catalase as reporter enzyme

33. L. Müller, M.-C. Reinnig, H. Hayen, T. Hoffmann, Rapid Commun. Mass Spectrom., 23 (2009) 971-979.
Characterization of oligomeric compounds in secondary organic aerosol using liquid chromatography to electrospray ionization-Fourier transform ion cyclotron resonance-mass spectrometry

32. Z. Pedrero,Y. Madrid,C., Camara, E. Schram, J. Luten, I. Feldmann, L. Wäntig, H. Hayen, N. Jakubowski, J. of Anal. At. Spectrom., 24 (2009) 775-784.
Screening of selenium containing proteins in the soluble fraction of African catfish (Clarias gariepinus) fillets by laser ablation-ICP-MS after SDS-PAGE and electro-blotting onto membranes

31. E.-M. Hein, L. M. Blank, J. Heyland, J. I. Baumbach, A. Schmid, H. Hayen, Rapid Commun. Mass Spectrom., 23 (2009) 1636-1646.
Glycerophospholipid profiling by high-performance liquid chromatography/mass spectrometry using exact mass measurements and multi-stage mass spectrometric fragmentation experiments in parallel

30. M. A. Mohamed, M. R. Mahmoud, H. Hayen, Z. Naturforsch. 64c (2009), 789-808.
Evaluation of anti-nociceptive and anti-inflammatory activities of a new triterpene saponin from bauhinia variegata leaves

29. M. Grote, D. H. Meriç, G. Langenkämper, H. Hayen, T. Betsche, M. Freitag, J. Verb. Lebensmittelsicherh., 4 (2009) 287-304.
Untersuchungen zum Transfer pharmakologisch wirksamer Substanzen aus der Nutztierhaltung in Porree und Weißkohl

28. N. H. Schebb, D. Falck, H. Faber, E.-M. Hein, U. Karst, H. Hayen, J. Chromatogr. A., 1216 (2009) 5249–5255.
Fast method for monitoring phospholipase A2 activity by liquid chromatography-electrospray ionization mass spectrometry

27. H. Hayen, A. Michels, J. Franzke, Anal. Chem., 81 (2009) 10239-10245.
Dielectric barrier discharge ionization for liquid chromatography / mass Spectrometry

26. B. Seiwert, H. Hayen, U. Karst , J. Am. Soc. Mass Spectrom., 19 (2008) 1-7.
Differential labeling of free and disulfide-bound thiol functions in proteins

25. M. A. Mohamed, W. S. Ahamed, M. M. El-Said, H. Hayen, Nat. Prod. Commun., 3 (2008) 193-198.
New acylated flavonol diglycosides of cynanchum acutum

24. N. H. Schebb, D. Fischer, E.-M. Hein, H. Hayen, J. Krieglstein, S. Klumpp, U. Karst, J. Chromatogr. A., 1183 (2008) 1000-1007.
Fast sample preparation and liquid chromatography-tandem mass spectrometry method for assaying cell lysate acetylcholine

23. M. Freitag, D. H. Yolcu, H. Hayen, T. Betsche, M. Grote, J. Verb. Lebensmittelsicherh., 3 (2008) 174-184.
Screening zum Antibiotika-Transfer aus dem Boden in Getreide in Regionen Nordrhein-Westfalens mit großen Viehbeständen

22. N. Jakubowski, J. Messerschmidt, M. G. Añorbe, L. Wäntig, H. Hayen, P. H. Roos, J. of Anal. At. Spectrom., 23 (2008) 1487-1496.
Labelling of proteins by use of iodination and detection by ICP-MS

21. N. Jakubowski, L. Wäntig, H. Hayen, A. Venkatachalam, A. von Bohlen, P. H. Roos, A. Manz, J. of Anal. At. Spectrom., 23 (2008) 1497-1507.
Labelling of proteins with 2-(4-isothiocyanatobenzyl)-1,4,7,10-tetraazacyclododecane-1,4,7,10-tetraacetic acid and lanthanides and detection by ICP-MS

20. G. Weber, N. von Wirén, H. Hayen, BioMetals, 21 (2008) 503-513.
Investigation of ascorbate-mediated iron release from ferric phytosiderophores in the presence of nicotianamine

19. G. Weber, N. von Wirén, H. Hayen, J. Sep. Sci., 31 (2008) 1615-1622
Hydrophilic interaction chromatography of small metal species in plants using sulfobetaine and phosphorylcholine type zwitterionic stationary phases

18. W. Lohmann, H. Hayen, U. Karst , Anal. Chem., 80 (2008) 9714-9719.
Covalent protein modification by reactive drug metabolites using on-line electro-chemistry / liquid chromatography / mass spectrometry

17. A. R. Meda, E. Scheuermann, U. Prechsl, B. Erenoglu, G. Schaaf, H. Hayen, G. Weber, N. von Wirén; Plant Physiol. 143 (2007) 1761-1773.
Iron acquisition by phytosiderophores contributes to cadmium tolerance

16. E. Torres, H. Hayen, C. M. Niemeyer, Biochem. Biophys. Res. Commun. 355 (2007) 286-293.
Evaluation of cytochrome P450BSß reactivity against polycyclic aromatic hydrocarbons and drugs

15. S. Wiese, T. Gronemeyer, R. Ofman, M. Kunze, C. P. Grou, J. A. Almeida, M. Eisenacher, C. Stephan, H. Hayen, M. Pawlas, C. Bunse, L. Schollenberger, T. Korosec, H. R. Waterham, W. Schliebs, R. Erdmann, J. Berger, H. E. Meyer, W. Just, J. E. Azevedo, R. J. A. Wanders, B. Warscheid, Mol. Cell. Proteomics, 6 (2007) 2045-2057.
Proteomic characterization of mouse kidney peroxisomes by tandem mass spectrometry and protein correlation profiling

14. G. Weber, N. von Wirén, H. Hayen, Rapid Commun. Mass Spectrom. 20 (2006) 973-980.
Analysis of iron(II) / iron(III) phytosiderophore-complexes by nano-electrospray-Fourier transform ion cyclotron resonance-mass spectrometry

13. H. Henneken, H. Hayen, M. Vogel, U. Karst, J. Chromatogr. A, 1134 (2006) 112-121.
Validation of a diffusive sampling method for airborne low-molecular isocyanates using 4-nitro-7-piperazinobenzo-2-oxa-1,3-diazole-impregnated filters and liquid chromato-graphy-tandem mass spectrometry

12. Y. Xuan, H. Hayen, E. Scheuermann, N. von Wirén, G. Weber, J. Chromatogr. A., 1136 (2006) 73-81.
Separation and identification of phytosiderophores and their metal complexes in plants by zwitterionic hydrophilic interaction liquid chromatography coupled to electrospray-ionization mass spectrometry

11. B. Blankert, H. Hayen, S. M. van Leeuwen, U. Karst, E. Bodoki, S. Lotrean, R. Sandulescu, N. Mora Diez, O. Dominguez, J. Arcos, J.-M. Kauffmann, Electroanalysis 17 (2005) 501-510.
Electrochemical, chemical and enzymatic oxidations of phenothiazines

10. H. Hayen, D. A. Volmer, Rapid Commun. Mass Spectrom. 19 (2005) 711-720.
Rapid identification of siderophores by combined thin-layer chromatography/matrix-assisted laser desorption/ionization mass spectrometry

9. H. Hayen, D. A. Volmer, Anal. Bioanal. Chem. 385 (2006) 606-611.
Different iron-chelating properties of pyochelin diastereoisomers revealed by LC/MS

8. A. A. Dechamps, A. A. van Appeldorn, H. Hayen, J. D. de Bruijn, D. W. Grijpma, J. Feijen, U. Karst, Biomaterials 25 (2004) 247-258.
In vivo and in vitro degradation of poly(ether ester) block copolymers based on poly(ethylene glycol) and poly(butylene terephthalate)

7. S. M. van Leeuwen, H. Hayen, U. Karst, Anal. Bioanal. Chem. 378 (2004) 917-925.
Liquid chromatography/electrochemistry/mass spectrometry of polycyclic aromatic hydrocarbons

6. H. Hayen, A. A. Deschamps, D. W. Grijpma, J. Feijen, U. Karst, J. Chromatogr. A, 1029 (2004) 29-36.
LC/MS studies on the in vitro degradation of poly(ether ester) block copolymers

5. H. Hayen, M. M. Álvarez-Grima, S. C. Debnath, J. W. M. Noordermeer, U. Karst, Anal. Chem. 76 (2004) 1063-1068.
Liquid chromatography/coordination ionspray-mass spectrometry (LC/CIS-MS) for the analysis of rubber vulcanization products

4. J. Meyer, A. Liesener, S. Götz, H. Hayen, U. Karst, Anal. Chem. 75 (2003) 922-926.
Liquid chromatography with on-line electrochemical derivatization and fluorescence detection for the determination of phenols

3. H. Hayen, U. Karst, Anal. Chem. 75 (2003) 4833-4840.
Analysis of phenothiazine and its derivatives using LC/electrochemistry/MS and LC/electrochemistry/fluorescence

2. H. Hayen, N. Jachmann, M. Vogel, U. Karst, Analyst 128 (2003) 1365-1372.
LC-electron capture-APCI(-)-MS determination of nitrobenzoxadiazole derivatives

1. H. Hayen, N. Jachmann, M. Vogel, U. Karst, Analyst 127 (2002) 1027-1030.
LC-electron capture APCI-MS for the determination of nitroaromatic compounds

Other Publications

33. G. Gauglitz, H. Hayen, M. Jäger, A. E. Kramell, F.-M. Matysik, M. Schöning, P. Wagner, Nachr. Chem. 72 (2024) 52-64.
Trendbericht Analytische Chemie 2024

32. S. Schneider, S. Hammann, H. Hayen, Lebensmittelchemie 77 (2023) 145-149.
Bestimmung von polaren Lipiden in Weizen und Hafer

31. J. Scholz, H. Hayen, chrom+food FORUM 04 (2023).
Sphingolipide in vielfachen Dimensionen - Lipidanalytik mittels Flüssigchromatographie und Massenspektrometrie

30. V. Schwantes, H. Hayen, chrom+food FORUM 09 (2022).
Festphasenextraktion versus zweidimensionale HPLC - Anwendungen in der Lipidanalytik

29. J. Scholz, J. Semesdiek, W. Jiang, H. Hayen, LCGC Europe, 34 (2021) 517-518.
HILIC Empowered Targeted Analysis of Sphingolipids by Online Two-Dimensional HILIC–Reversed-Phase LC–MS

28. A. Lipphardt, K. Scholz, H. Hayen, Lebensmittelchemie 75 (2021) 64-67.
Glykolipidbasierte Biotenside und deren Identifizierung und Quantifizierung mittels überkritischer Fluidchromatografie

27. K. Scholz, W. Jiang, H. Hayen, LCGC Europe, 33 (2020) 618-619.
Supercritical Fluid Chromatography Analysis of Polyol Biosurfactants with iHILIC®-Fusion Column and Mass Spectrometry

26. P. O. Helmer, C. M. Wienken, W. Jiang, H. Hayen, LCGC Europe, 33 (2020) 212-213.
Tailored Analysis of Phospholipid Classes Using iHILIC-Fusion(+) as First Dimension for Online Two-Dimensional HILIC–Reversed-Phase LC–MS

25. S. Hammann, A. Korf, M. Froning, H. Hayen und L. J. E. Cramp., Deutsche Lebensm. Rundschau, 5 (2019) 434-443.
Lipide heute und gestern - Moderne analytische Chemie als Schlüssel zur Rekonstruktion vergangener Ernährungsgewohnheiten

24. P. O. Helmer, W. Jiang, H. Hayen, LCGC Europe, 32 (2019) 659-660
Efficient Separation of Polar and Nonpolar Lipid Classes Utilizing iSPE®-HILIC Material for Solid-Phase Extraction

23. K. Scholz, M. Baune, H. Hayen, W. Jiang, LCGC Europe, The Applications Book, 3 (2019) 164-165.
Separation and identification of non-covalent metal complexes from bacteria by HILIC–MS

22. C. Vosse, H. Hayen, chrom+food FORUM 03 (2019) 8-11.
Trennung und Identifizierung von Phospholipiden

21. S. Hamann, L. Cramp, A. Korf, H. Hayen, chrom+food FORUM 03 (2019) 27-29.
Umfassende Analyse von Getreidelipiden

20. K. Scholz, H. Hayen, chrom+food FORUM 09 (2018) 29-31.
HILIC-MS zur Identifizierung und Strukturaufklärung von Eisenkomplexen

19.  C. Vosse, C. Wienken, H. Hayen, W. Jiang, LCGC Europe, The Applications Book, 9 (2018) 529-530.
Analysis of phospholipid classes by iHILIC®-Fusion

18.  A. Schriewer, K. J. Theilen, H. Hayen, W. Jiang, LCGC Europe, The Applications Book, 5 (2017) 386-387.
Direct Analysis of Amino Acids by HILIC–ESI-MS

17. P. O. Helmer, B. Behrens, H. Hayen, chrom+food FORUM 04 (2017) 23-25.
Biotensid-Charakterisierung mittels LC-MS/MS - Online-Probenvorbereitung mittels Turbulent Flow Chromatography

16. J. Henschel, A. Schriewer, H. Hayen, W. Jiang, LCGC Europe, The Applications Book, 4 (2016) 401.
Analysis of artificial sweeteners by HILIC–MS method

15. B. Hagenhoff, U. Karst, S. Ohla, S. Nagl, D. Belder, T. Teutenberg, H. Hayen, M. Sperling, M. Maiwald, C. Huber, M. Vogel, Nachr. Chem. 64 (2016) 497-508.
Trendbericht Analytische Chemie 2014/2015

14. S. Hagenhoff, B. Gilbert-López, J. F. García-Reyes, J. Franzke, A. Molina-Díaz, H. Hayen, chrom+food FORUM 03 (2015) 27-30.
Rückstandsanalytik mittels LC-MS - Mikroplasmen als Alternative zur Electrospray-Ionisierung

13. G. Dierkes, H. Hayen, GIT 1 (2013) 16-18
Qualitätsbewertung von Olivenöl über das Aromastoffprofil - Ein alternativer Ansatz zur Sensorik

12. G. Weber, J. Künnemeyer, H. Hayen, Labor & More, ChromChat 2010
HILIC – Metallen auf der Spur

11. H. Hayen, GIT Separation 1 (2010) 3 (Editorial).
Kopplungstechniken im Dienste des Verbraucherschutzes

10. H. Hayen, Nachr. Chem. 58 (2010) 461-465.
HILIC - Polare Verbindungen trennen

9. D. H. Yolcu, H. Hayen, M. Grote, LaborPraxis, March 2008, 28-30.
Bestimmung von Antibiotika-Rückständen in Getreide

8. G. Weber, H. Hayen, GIT Separation 1 (2008) 24-26.

HILIC-MS von nicht kovalenten Metallspezies

7. M. Grote, C. Schwake-Anduschus, R. Michel, G. Langenkämper, T. Betsche, H. Hayen, W. Heyser, M. Freitag, Münchener Beiträge zur Abwasser-, Fischerei- und Flussbiologie, Tierarzneimittel in der Umwelt, 58 (2007) 1145-1147, Oldenbourg München.
Aufnahme und Transport von Tierarzneistoffen in Nutzpflanzen

6. B. Seiwert, S. M. van Leeuwen, H. Hayen, M. Vogel, U. Karst, Die Aktuelle Wochenschau der GDCh 26 (2005).
Flüssigchromatographie und Massenspektrometrie für die Analytik unpolarer Verbindungen

5. M. Vogel, S. M. van Leeuwen, B. Seiwert, H. Hayen, U. Karst, Nachr. Chem. 53 (2005) 1145-1147.
Mit LC/Elektrochemie/MS unpolare Substanzen analysieren

4. H. Hayen, U. Karst, GIT Laborfachzeitschrift 1 (2004) 30-33.
Elektroneneinfang-Ionisierung in der LC/MS

3. H. Hayen, M. Vogel, U. Karst, Gefahrstoffe Reinhaltung der Luft 63 (2003) 295-298.
Recent developments in the determination of formaldehyde in air samples using derivatizing agents

2. H. Hayen, U. Karst, J. Chromatogr. A 1000 (2003) 549-565.
Strategies for the liquid chromatographic-mass spectrometric analysis of non-polar compounds 

1. H. Hayen, S. M. van Leeuwen, G. Zurek, U. Karst, GIT Separation 22 (2002) 52-54.
HPLC/MS für die Analytik unpolarer Verbindungen