Preclinical & Clinical Imaging

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    Mediso nanoScan PET/MRI

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Integrated Positron-Emission-Tomography (PET) and Magnetic Resonance Imaging (MRI)
    • Non-invasive 3D imaging of radiolabeled tracers in living mice combined with anatomical imaging
    • PET:  Molecular imaging of (patho-)physiological processes, e.g. cell metabolism, receptors, transporters, or cell tracking.  Quantitative tracer detection up to few hours  after injection, dependent on the half-life of the coupled positron emitting radioisotope  (F-18, C-11, Ga-68, N-13), Spatial resolution: about 1 mm
    • MRI: Anatomical imaging, Magnetic field strength: 1Tesla
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    Mediso nanoScan SPECT/CT

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Integrated Single-Photon-Emission-Computed-Tomography (SPECT) and Computed Tomography (CT)
    • Non-invasive 3D imaging of radiolabeled tracers in living mice combined with anatomical imaging
    • SPECT:  Molecular imaging of (patho-)physiological processes, e.g. cell metabolism, receptors, transporters, or cell tracking.  Quantitative tracer detection up to several days after tracer injection, dependent on the half-life of the coupled gamma emitting radioisotope  (Tc-99m, In-111, I-123)
    • CT: Anatomical imaging
    • SPECT equipment: Multi-Pinhole-Collimators for different applications (APT51, APT52, APT62, APT66), Spatial resolution: 0.5 – 1.5 mm
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    quadHIDAC PET

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Positron-Emission-Tomography (PET)
    • Non-invasive 3D imaging of radiolabeled tracers in living mice combined with anatomical imaging
    • PET:  Molecular imaging of (patho-)physiological processes, e.g. cell metabolism, receptors, transporters, or cell tracking.  Quantitative tracer detection up to few hours  after injection, dependent on the half-life of the coupled positron emitting radioisotope  (F-18, C-11, Ga-68, N-13)
    • Spatial resolution: below 1 mm
    • Field of view: 16 cm  x 28 cm
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    Siemens Inveon CT

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Non-invasive computed tomography (CT) of living mice
    • Anatomical imaging
    • Spatial resolution: 80µm (down to 25µm)
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    Bruker MS FX Pro

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sonja Schelhaas, Tel.: 0251 83- 49312, sonja.schelhaas@uni-muenster.de

    Applications & Info:

    • 2D Fluorescence reflectance imaging (FRI) of living mice or ex vivo organs
    • X-ray imaging
    • Filter specifications: 28 excitation filters (20 nm bandwidth, 410 nm – 760 nm), 6 emission filters (35-40 nm bandwidth, 535 nm, 600 nm, 700 nm, 750 nm, 790 nm, 830 nm)
    • Multimodal animal rotation system (MARS)
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    Perkin Elmer IVIS Spectrum

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sonja Schelhaas, Tel.: 0251 83- 49312, sonja.schelhaas@uni-muenster.de

    Applications & Info:

    • 2D Bioluminescence and fluorescence reflectance imaging of living mice or ex vivo organs
    • Filter specifications: 10 excitation filters (30 nm bandwidth, 415 nm – 760 nm), 18 emission filters (20 nm bandwidth, 490 nm – 850 nm)
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    Visualsonics Vevo2100 LAZR

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person:
    Sven Hermann
    Tel.: 0251 83- 49303
    shermann@uni-muenster.de

    Applications & Info:

    • High resolution ultrasound (US) & photoacoustic imaging (PAI)
    • US: Non-invasive 2D anatomic and functional imaging in living mice
    • PAI: Non-invasive 2D detection of photoabsorbers (e.g. fluorescent dye IRDye800cw) in living mice
    Transducers
    Frequency Image depth (max) Spatial resolution
    MS250 (US) / LZ250 (PAI/US) 13-24 MHz 30 mm 75µm (axial), 165µm (lateral)
    MS400 (US) 18-38 MHz 20 mm 50µm (axial), 110 µm (lateral)
    MS550D (US) / LZ550 (PAI/US) 22-55 MHz 15 mm 40 µm (axial), 90µm (lateral)
    MS700 (US) 30-70 MHz 12 mm 30µm (axial), 75µm (lateral)
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    iThera MSOT inVision

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Multispectral Optoacoustic Tomography (MSOT)
    • Non-invasive 3D detection of photoabsorbers (e.g. fluorescent dye IRDye800cw) in living mice
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    Biospace µ-Imager

    Location: European Institute for Molecular Imaging, Waldeyerstr. 15
    Contact Person: Sven Hermann, Tel.: 0251 83- 49303, shermann@uni-muenster.de

    Applications & Info:

    • Digital autoradiography camera
    • Measurement of radiotracer distribution in tissue samples (cryosections)
  • Heidelberg Engineering OCT Spectralis

    Location: University Eye Hospital, Domagkstr. 15
    Group: AG Eter
    Contact Person: PD Dr. Peter Heiduschka
    Tel.: 0251 83-57532, peter.heiduschka@ukmuenster.de

    Applications & Info:

    • In-vivo Imaging of the retina by infrared scanning laser ophthalmoscopy, optical coherence tomography, and fluorescence angiography
  • Vectra 3.0 Automated Quantitative Pathology Imaging System, 200 Slide, Perkin Elmer

    Location: Gerhard Domagk Institute of Pathology
    Group: AG Rössig, in cooperation with AG Wardelmann
    Contact Person: Prof. Wolfgang Hartmann
    Tel.: 0251 83-58479, wolfgang.hartmann@ukmuenster.de

    Applications & Info:

    • simultaneous detection of multiple markers
    • detailed in situ analyses of the cellular composition of individual tissues and tumors
    • spatial relationships of immune phenotypes on (tumor) biopsies