• Participation in “Cells in Motion”

    • Research interests: cell organisation, actin cytoskeleton, calcium signalling, plasma membrane organisation, intracellular transport, mathematical and physical principles of cell patterning
    • Cells in Motion Professor of Multiscale Imaging and Cell Biology
    • Supervisor in the CiM-IMPRS Graduate Programme
    • Member of the Imaging Network – Microscopy

  • News & views

  • Patents in the research focus “cell dynamics and imaging”

    • Wedlich-Söldner R, Sixt M, Riedl J, Crevenna A. Peptide for determining actin structures in living cells. WO 2009/068295; 04/06/2009. EP 2215109; 11/08/2010. US 2011/0111445; 12/05/2011.

  • Papers in the research focus “cell dynamics and imaging”

    2019

    Mietkowska M, Schuberth C, Wedlich-Söldner R, Gerke V. Actin dynamics during Ca(2+)-dependent exocytosis of endothelial Weibel-Palade bodies. Biochim Biophys Acta Mol Cell Res 2019;1866: 1218-1229. Abstract

    2018

    Busto JV, Elting A, Haase D, Spira F, Kuhlman J, Schafer-Herte M, Wedlich-Söldner R. Lateral plasma membrane compartmentalization links protein function and turnover. Embo J 2018;37: e99473. Abstract
    Prystopiuk V, Fels B, Simon CS, Liashkovich I, Pasrednik D, Kronlage C, Wedlich-Söldner R, Oberleithner H, Fels J. A two-phase response of endothelial cells to hydrostatic pressure. J Cell Sci 2018;131: jcs206920. Abstract

    2016

    Wales P, Schuberth CE, Aufschnaiter R, Fels J, Garcia-Aguilar I, Janning A, Dlugos CP, Schafer-Herte M, Klingner C, Walte M, Kuhlmann J, Menis E, Hockaday Kang L, Maier KC, Hou W, Russo A, Higgs HN, Pavenstadt H, Vogl T, Roth J, Qualmann B, Kessels MM, Martin DE, Mulder B, Wedlich-Söldner R. Calcium-mediated actin reset (CaAR) mediates acute cell adaptations. Elife 2016;5: e19850. Abstract

    2015

    Crevenna AH, Arciniega M, Dupont A, Mizuno N, Kowalska K, Lange OF, Wedlich-Söldner R, Lamb DC. Side-binding proteins modulate actin filament dynamics. Elife 2015;4: e04599. Abstract
    Schuberth C, Wedlich-Söldner R. Building a patchwork - The yeast plasma membrane as model to study lateral domain formation. Biochim Biophys Acta 2015;1853: 767-774. Abstract

    2014

    Dominguez-Escobar J, Wolf D, Fritz G, Hofler C, Wedlich-Söldner R, Mascher T. Subcellular localization, interactions and dynamics of the phage-shock protein-like Lia response in Bacillus subtilis. Mol Microbiol 2014;92: 716-732. Abstract
    Klingner C, Cherian AV, Fels J, Diesinger PM, Aufschnaiter R, Maghelli N, Keil T, Beck G, Tolic-Norrelykke IM, Bathe M, Wedlich-Söldner R. Isotropic actomyosin dynamics promote organization of the apical cell cortex in epithelial cells. J Cell Biol 2014;207: 107-121. Abstract
    Rueff A-S, Chastanet A, Dominguez-Escobar J, Yao Z, Yates J, Prejean M-V, Delumeau O, Noirot P, Wedlich-Söldner R, Filipe SR, Carballido-Lopez R. An early cytoplasmic step of peptidoglycan synthesis is associated to MreB in Bacillus subtilis. Mol Microbiol 2014;91: 348-362. Abstract
    Wedlich-Söldner R. A longer life for yeast with good memory. Dev Cell 2014;31: 391-392. Abstract

    2013

    Abdelhady S, Kitambi SS, Lundin V, Aufschnaiter R, Sekyrova P, Sinha I, Lundgren KT, Castelo-Branco G, Linnarsson S, Wedlich-Söldner R, Teixeira A, Andäng M. Erg channel is critical in controlling cell volume during cell cycle in embryonic stem cells. PLoS One 2013;8: e72409. Abstract
    Crevenna AH, Naredi-Rainer N, Schonichen A, Dzubiella J, Barber DL, Lamb DC, Wedlich-Söldner R. Electrostatics control actin filament nucleation and elongation kinetics. J Biol Chem 2013;288: 12102-12113. Abstract
    Freisinger T, Klunder B, Johnson J, Müller N, Pichler G, Beck G, Costanzo M, Boone C, Cerione RA, Frey E, Wedlich-Söldner R. Establishment of a robust single axis of cell polarity by coupling multiple positive feedback loops. Nat Commun 2013;4: 1807. Abstract
    Klünder B, Freisinger T, Wedlich-Söldner R, Frey E. GDI-Mediated Cell Polarization in Yeast Provides Precise Spatial and Temporal Control of Cdc42 Signaling. PLoS Comput Biol 2013: e1003396. Abstract