![Inspiration to the chemists: the eye<address>© Colourbox.de/A. Tiplyashin</address>](http://www.uni-muenster.de/news/data/img/2015/09/7859-yz84dvFK-webL.jpg)
Inspired by the chemistry of the eye
Nature can do it, and chemists in the lab often dream of doing it: producing substances simply and ecologically – as far as possible without any undesirable side-products. A team of researchers from Münster University has now succeeded in turning to its advantage a chemical reaction which takes place in the eye and enables us to see light and dark. This process, say the researchers, is of great interest for the chemical industry because it could be used to create special variants (isomers) of important carbon compounds which need a lot of energy to be produced by other means.
In the eye, the light-absorbing pigment rhodopsin plays an elementary role as a light sensor. When light enters the eye, rhodopsin triggers a chemical signal chain, thereby activating the photoreceptor cells. “We were inspired by this process,” says Jan Metternich, a doctoral student of chemistry who carried out the study together with Dr. Ryan Gilmour, Professor of Chemical Biology in the “Cells in Motion” Cluster of Excellence at Münster University.
One of the central components of the light-absorbing pigment rhodopsin is retinal (“Vitamin A”). To activate the photoreceptor cells, however, a very special variant of the retinal molecule is needed. As a result of light entering the eye, it is converted into a second, very similar form, thereby starting off the chemical signal chain. “Isomers” are what chemists call the different forms of a molecule.
Original publication:
Jan B. Metternich and Ryan Gilmour (2015): A Bio-Inspired, Catalytic E → Z Isomerization of Activated Olefin. J. Am. Chem. Soc.; DOI: 10.1021/jacs.5b07136